PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

HL.SW.v1.0.G001718.1

Organism

Humulus lupulus

Taxonomic ID

3486

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus

Family

bHLH

Protein Properties

Length: 401aa MW: 45890.7 Da PI: 4.8146

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
HL.SW.v1.0.G001718.1	genome	HOPBASE	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	36.4	9.3e-12	220	263	6	54
HHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHH CS HLH 6 nerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksL 54 ++ErrRR+r+N++++ Lr+++Pk + K++ +iL +++Y+k+L HL.SW.v1.0.G001718.1 220 LMAERRRRKRLNDRLSMLRSIVPKiS------KMDRTSILGDTIDYMKEL 263 589*******************66......**************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	15.491	214	263	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	9.16E-16	219	288	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	1.7E-9	220	263	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	8.5E-12	220	269	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.8E-15	221	284	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.19E-4	221	268	No hit	No description
CDD	cd04873	0.00159	312	353	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 401 aa Download sequence Send to blast
MDQIKPRPFG FYLYNPPLDA TSSYQGTSTN VTFPREREME LNEHGFLEEH LAFRRDAWEA 60 IPAEMNELFS STELGFDYYY DQNPSTIFPN NSSCSQEIIS PQLELSGFNN YSFNEVYCPS 120 SNEILVPQFT TNSSYNTATA TTHFDTLSFY PHIQEELLLK TLEKEELGIL DDEIHNLETQ 180 ASCKMEPVQS PDYIPVFNMG LPLGRKNRAK KLQGQPSKNL MAERRRRKRL NDRLSMLRSI 240 VPKISKMDRT SILGDTIDYM KELLERISNL QQEINASSSQ FNELRLFKDV KPNEVLVRNS 300 PKFDVERRDV DTRIEICCAG KPGLLFSTVT SLDALGLEIQ QCVISCFNDF SMQASCSEDL 360 EKRALNNSED IKQALFRNAG YGGRCIDGFF KSLYFQSAER *

Sequence ? help Back to Top

Protein Sequence Length: 401 aa Download sequence Send to blast

MDQIKPRPFG FYLYNPPLDA TSSYQGTSTN VTFPREREME LNEHGFLEEH LAFRRDAWEA  60
IPAEMNELFS STELGFDYYY DQNPSTIFPN NSSCSQEIIS PQLELSGFNN YSFNEVYCPS  120
SNEILVPQFT TNSSYNTATA TTHFDTLSFY PHIQEELLLK TLEKEELGIL DDEIHNLETQ  180
ASCKMEPVQS PDYIPVFNMG LPLGRKNRAK KLQGQPSKNL MAERRRRKRL NDRLSMLRSI  240
VPKISKMDRT SILGDTIDYM KELLERISNL QQEINASSSQ FNELRLFKDV KPNEVLVRNS  300
PKFDVERRDV DTRIEICCAG KPGLLFSTVT SLDALGLEIQ QCVISCFNDF SMQASCSEDL  360
EKRALNNSED IKQALFRNAG YGGRCIDGFF KSLYFQSAER *

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	222	229	ERRRRKRL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. May be involved in the differentiation of stomatal guard cells. {ECO:0000269\|PubMed:17088607}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015867675.1	1e-153	transcription factor bHLH93-like
Swissprot	Q9LSL1	4e-80	BH093_ARATH; Transcription factor bHLH93
TrEMBL	A0A2P5EJU1	0.0	A0A2P5EJU1_TREOI; Basic helix-loop-helix transcription factor
STRING	EOY15558	1e-149	(Theobroma cacao)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF1186	34	103

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G65640.1	6e-82	beta HLH protein 93

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Sharma N, et al. NO FLOWERING IN SHORT DAY (NFL) is a bHLH transcription factor that promotes flowering specifically under short-day conditions in Arabidopsis. Development, 2016. 143(4): p. 682-90 [PMID:26758694] Chen YS, et al. Two MYB-related transcription factors play opposite roles in sugar signaling in Arabidopsis. Plant Mol. Biol., 2017. 93(3): p. 299-311 [PMID:27866313] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]