PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID HL.SW.v1.0.G000208.1
Organism
Humulus lupulus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Humulus
Family NAC
Protein Properties Length: 374aa    MW: 42416.2 Da    PI: 7.2517
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
HL.SW.v1.0.G000208.1genomeHOPBASEView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM173.94.7e-54131431129
                   NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk..kvka.eekewyfFskrdkkyatgkrknratksgyWkat 86 
                           +ppGfrFhPtdeel+ +yL+kkv+ ++++l +vi+evd++k+ePwdL++  ++ +  ++ewyfFs++dkky+tg+r+nrat++g+Wkat
  HL.SW.v1.0.G000208.1  13 VPPGFRFHPTDEELLYYYLRKKVSYEPIDL-DVIREVDLNKLEPWDLKEkcRIGSgPQNEWYFFSHKDKKYPTGTRTNRATAAGFWKAT 100
                           69****************************.9***************952444443456****************************** PP

                   NAM  87 gkdkevlskkgelvglkktLvfykgrapkgektdWvmheyrle 129
                           g+dk+++ ++ + +g++ktLvfy+grap+g+ktdW+mheyrle
  HL.SW.v1.0.G000208.1 101 GRDKAIHLSDAKRIGMRKTLVFYTGRAPHGQKTDWIMHEYRLE 143
                           *****************************************85 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019414.05E-609167IPR003441NAC domain
PROSITE profilePS5100558.64813167IPR003441NAC domain
PfamPF023653.1E-2814142IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003002Biological Processregionalization
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009834Biological Processplant-type secondary cell wall biogenesis
GO:0010455Biological Processpositive regulation of cell fate commitment
GO:0048829Biological Processroot cap development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 374 aa     Download sequence    Send to blast
MNLGEGSNGQ LTVPPGFRFH PTDEELLYYY LRKKVSYEPI DLDVIREVDL NKLEPWDLKE  60
KCRIGSGPQN EWYFFSHKDK KYPTGTRTNR ATAAGFWKAT GRDKAIHLSD AKRIGMRKTL  120
VFYTGRAPHG QKTDWIMHEY RLEDNDTTTT ADQIQEDGWV VCRVFKKKNH NRSFQPELAN  180
NNNNQEELSY HPQMKESVGT SAPLVLDHHH QHLHHHQPKH FQQLYDNYTF DHHGSMHLPQ  240
LFSPESAVNP AAAAAATTFA SPASGGISLN TIDLECSHNL LRLTSNGCGG MQVPAAPERF  300
NGGDWTFLDK LLANSNHHQQ QHLALQAKCH PSSSSDHHHQ VAHDHDHVGS TTTQRLFPFQ  360
YLGCDSDILK FSK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A1e-511016914167NO APICAL MERISTEM PROTEIN
1ut4_B1e-511016914167NO APICAL MERISTEM PROTEIN
1ut7_A1e-511016914167NO APICAL MERISTEM PROTEIN
1ut7_B1e-511016914167NO APICAL MERISTEM PROTEIN
3swm_A2e-511016917170NAC domain-containing protein 19
3swm_B2e-511016917170NAC domain-containing protein 19
3swm_C2e-511016917170NAC domain-containing protein 19
3swm_D2e-511016917170NAC domain-containing protein 19
3swp_A2e-511016917170NAC domain-containing protein 19
3swp_B2e-511016917170NAC domain-containing protein 19
3swp_C2e-511016917170NAC domain-containing protein 19
3swp_D2e-511016917170NAC domain-containing protein 19
4dul_A1e-511016914167NAC domain-containing protein 19
4dul_B1e-511016914167NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription regulator. Together with BRN1 and BRN2, regulates cellular maturation of root cap. Represses stem cell-like divisions in the root cap daughter cells, and thus promotes daughter cell fate. Inhibits expression of its positive regulator FEZ in a feedback loop for controlled switches in cell division plane. Promotes the expression of genes involved in secondary cell walls (SCW) biosynthesis. {ECO:0000269|PubMed:19081078, ECO:0000269|PubMed:20197506}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00250DAPTransfer from AT1G79580Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By FEZ in oriented-divised root cap stem cells. {ECO:0000269|PubMed:19081078}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020418176.11e-173protein SOMBRERO isoform X2
SwissprotQ9MA171e-126SMB_ARATH; Protein SOMBRERO
TrEMBLA0A2P5B6010.0A0A2P5B601_TREOI; NAC domain containing protein
STRINGXP_009368592.11e-172(Pyrus x bretschneideri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF72043447
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G79580.32e-94NAC family protein
Publications ? help Back to Top
  1. Fendrych M, et al.
    Programmed cell death controlled by ANAC033/SOMBRERO determines root cap organ size in Arabidopsis.
    Curr. Biol., 2014. 24(9): p. 931-40
    [PMID:24726156]
  2. Bennett T,van den Toorn A,Willemsen V,Scheres B
    Precise control of plant stem cell activity through parallel regulatory inputs.
    Development, 2014. 141(21): p. 4055-64
    [PMID:25256342]
  3. Karve R,Suárez-Román F,Iyer-Pascuzzi AS
    The Transcription Factor NIN-LIKE PROTEIN7 Controls Border-Like Cell Release.
    Plant Physiol., 2016. 171(3): p. 2101-11
    [PMID:27221617]
  4. Kamiya M, et al.
    Control of root cap maturation and cell detachment by BEARSKIN transcription factors in Arabidopsis.
    Development, 2016. 143(21): p. 4063-4072
    [PMID:27803060]