PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Han007660
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Heliantheae alliance; Heliantheae; Helianthus
Family E2F/DP
Protein Properties Length: 186aa    MW: 20182.2 Da    PI: 8.4479
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Han#S48334234PU_refUnigeneView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP82.63.3e-2688168370
    E2F_TDP   3 eksLrlltqkflklleksee.givtlnevakeLvse................dvknkrRRiYDilNVLealnliekkekneirwk 70 
                +++Lr++++k   ++ek+e+ g++t+neva+eLv+e                d+kn+rRR+YD+lNVL+ +++i+k +k+ei+w+
  Han007660  88 GRGLRQFSMK---VCEKVESkGRTTYNEVADELVAEfsdpgdgdqapdqkqyDEKNIRRRVYDALNVLMPMDIISK-DKKEIQWR 168
                689*******...*****999*******************************************************.*******7 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.105.2E-4482174IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.2E-3286169IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023195.1E-2489168IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.26E-1989168IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 186 aa     Download sequence    Send to blast
MGSNDSLENA AANINPFAGG SRAPTRSTVS GQSVSTSGSA GSPSTRSDNT FLRLNHVDVV  60
GDDDAGSQGV AGKKKKRAQR ATGGDKGGRG LRQFSMKVCE KVESKGRTTY NEVADELVAE  120
FSDPGDGDQA PDQKQYDEKN IRRRVYDALN VLMPMDIISK DKKEIQWRSL PRTSLNDIEE  180
TKSERL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B1e-3880174193PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed during the whole cell cycle. {ECO:0000269|PubMed:11669580}.
UniprotTISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:16920782}.
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_022024076.11e-129transcription factor-like protein DPB
SwissprotQ9FNY27e-80DPB_ARATH; Transcription factor-like protein DPB
TrEMBLA0A251VH551e-128A0A251VH55_HELAN; Putative winged helix-turn-helix DNA-binding domain, Transcription factor DP
STRINGGLYMA11G01270.13e-85(Glycine max)
STRINGXP_010050871.17e-85(Eucalyptus grandis)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G03415.15e-72Transcription factor DP