PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KHN45568.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family LSD
Protein Properties Length: 176aa    MW: 18624.5 Da    PI: 8.4357
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KHN45568.1genomeTCUHKView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD143.84.2e-14731125
     zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                C+gCr++L YPrGA++V+CalC+tV
  KHN45568.1  7 CNGCRNILVYPRGATNVCCALCNTV 31
                ************************9 PP

2zf-LSD145.99.4e-154670125
     zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                CggC tlL+Y+rGA+sVRC++C+t+
  KHN45568.1 46 CGGCTTLLMYTRGATSVRCSCCHTI 70
                ***********************97 PP

3zf-LSD142.11.4e-1384106123
     zf-LSD1   1 CggCrtlLsYPrGApsVRCalCd 23 
                 C +Crt+L+YP+GA+sV+Ca+C 
  KHN45568.1  84 CTNCRTTLMYPYGASSVKCAICR 106
                 99********************7 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010533.3E-13434IPR005735Zinc finger, LSD1-type
PfamPF069431.4E-11731IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010531.3E-154373IPR005735Zinc finger, LSD1-type
PfamPF069433.0E-124670IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010533.8E-1182110IPR005735Zinc finger, LSD1-type
PfamPF069436.1E-1384108IPR005735Zinc finger, LSD1-type
Sequence ? help Back to Top
Protein Sequence    Length: 176 aa     Download sequence    Send to blast
MGSQLVCNGC RNILVYPRGA TNVCCALCNT VTSVPPPGMD MSQLYCGGCT TLLMYTRGAT  60
SVRCSCCHTI NLVPVLESNQ VIHCTNCRTT LMYPYGASSV KCAICRYITN VSMTNGRLPI  120
PVQRPNGTAN SGTVSSTSSS MPHSQSQTVV VENPMSVDSS GKLVSNVVVG VTTEKK
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKHN45568.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003546559.11e-123protein LSD1 isoform X2
RefseqXP_028202517.11e-123protein LSD1-like isoform X2
SwissprotP940771e-70LSD1_ARATH; Protein LSD1
TrEMBLA0A445GVM51e-124A0A445GVM5_GLYSO; Protein LSD1 isoform D (Fragment)
STRINGGLYMA15G22140.11e-114(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF40273361
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.73e-70LSD family protein
Publications ? help Back to Top
  1. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
    [PMID:18393445]
  2. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
    [PMID:26754794]
  3. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
    [PMID:28555890]
  4. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382
    [PMID:30461017]