PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KHN41462.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family LSD
Protein Properties Length: 174aa    MW: 18500.4 Da    PI: 8.4881
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KHN41462.1genomeTCUHKView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD141.52.2e-13731125
     zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                C+gCr +L YPrGA++V+CalC+t+
  KHN41462.1  7 CNGCRSILVYPRGATNVCCALCNTI 31
                ***********************97 PP

2zf-LSD145.99.2e-154670125
     zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                CggC tlL+Y+rGA+sVRC++C+t+
  KHN41462.1 46 CGGCTTLLMYTRGATSVRCSCCHTI 70
                ***********************97 PP

3zf-LSD1382.7e-1282103122
     zf-LSD1   1 CggCrtlLsYPrGApsVRCalC 22 
                 C +Crt+L+YP+GA+sV+Ca+C
  KHN41462.1  82 CANCRTTLMYPYGASSVKCAIC 103
                 9********************* PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010532.1E-12434IPR005735Zinc finger, LSD1-type
PfamPF069431.9E-11731IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010531.3E-154373IPR005735Zinc finger, LSD1-type
PfamPF069433.0E-124670IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010533.4E-1080107IPR005735Zinc finger, LSD1-type
PfamPF069437.4E-1282106IPR005735Zinc finger, LSD1-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0016787Molecular Functionhydrolase activity
Sequence ? help Back to Top
Protein Sequence    Length: 174 aa     Download sequence    Send to blast
MRSQLVCNGC RSILVYPRGA TNVCCALCNT ITSVPPPGMD MSQLYCGGCT TLLMYTRGAT  60
SVRCSCCHTI NLVPESNQVI HCANCRTTLM YPYGASSVKC AICCYITNIS MTNGRLSIPV  120
QRPNGTANSG TVSSTSSSMP YSQSQTVVVE NPMSVDSSGK LVRNVVVGVT TDKK
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKHN41462.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_003533828.11e-122protein LSD1 isoform X1
RefseqXP_028180956.11e-122protein LSD1-like
SwissprotP940771e-68LSD1_ARATH; Protein LSD1
TrEMBLA0A0B2SB221e-120A0A0B2SB22_GLYSO; Protein LSD1
TrEMBLA0A0R4J4241e-120A0A0R4J424_SOYBN; Uncharacterized protein
STRINGGLYMA09G10010.11e-121(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF40273361
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.73e-68LSD family protein
Publications ? help Back to Top
  1. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
    [PMID:18393445]
  2. Qi X, et al.
    Identification of a novel salt tolerance gene in wild soybean by whole-genome sequencing.
    Nat Commun, 2014. 5: p. 4340
    [PMID:25004933]
  3. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
    [PMID:26754794]
  4. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
    [PMID:28555890]
  5. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382
    [PMID:30461017]