PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

KHN41462.1

Organism

Glycine soja

Taxonomic ID

3848

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja

Family

LSD

Protein Properties

Length: 174aa MW: 18500.4 Da PI: 8.4881

Description

LSD family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
KHN41462.1	genome	TCUHK	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-LSD1	41.5	2.2e-13	7	31	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 C+gCr +L YPrGA++V+CalC+t+ KHN41462.1 7 CNGCRSILVYPRGATNVCCALCNTI 31 ***********************97 PP
2	zf-LSD1	45.9	9.2e-15	46	70	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 CggC tlL+Y+rGA+sVRC++C+t+ KHN41462.1 46 CGGCTTLLMYTRGATSVRCSCCHTI 70 ***********************97 PP
3	zf-LSD1	38	2.7e-12	82	103	1	22
zf-LSD1 1 CggCrtlLsYPrGApsVRCalC 22 C +Crt+L+YP+GA+sV+Ca+C KHN41462.1 82 CANCRTTLMYPYGASSVKCAIC 103 9********************* PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
TIGRFAMs	TIGR01053	2.1E-12	4	34	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	1.9E-11	7	31	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	1.3E-15	43	73	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	3.0E-12	46	70	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	3.4E-10	80	107	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	7.4E-12	82	106	IPR005735	Zinc finger, LSD1-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0016787	Molecular Function	hydrolase activity

Sequence ? help Back to Top
Protein Sequence Length: 174 aa Download sequence Send to blast
MRSQLVCNGC RSILVYPRGA TNVCCALCNT ITSVPPPGMD MSQLYCGGCT TLLMYTRGAT 60 SVRCSCCHTI NLVPESNQVI HCANCRTTLM YPYGASSVKC AICCYITNIS MTNGRLSIPV 120 QRPNGTANSG TVSSTSSSMP YSQSQTVVVE NPMSVDSSGK LVRNVVVGVT TDKK

Functional Description ? help Back to Top
Source	Description
UniProt	Negative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269\|PubMed:10550898, ECO:0000269\|PubMed:11595797, ECO:0000269\|PubMed:11844114, ECO:0000269\|PubMed:12732715, ECO:0000269\|PubMed:15347794, ECO:0000269\|PubMed:16957775, ECO:0000269\|PubMed:18055613, ECO:0000269\|PubMed:18790826, ECO:0000269\|PubMed:20456049, ECO:0000269\|PubMed:21097903}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	KHN41462.1

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By methyl viologen. {ECO:0000269\|PubMed:20456049}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_003533828.1	1e-122	protein LSD1 isoform X1
Refseq	XP_028180956.1	1e-122	protein LSD1-like
Swissprot	P94077	1e-68	LSD1_ARATH; Protein LSD1
TrEMBL	A0A0B2SB22	1e-120	A0A0B2SB22_GLYSO; Protein LSD1
TrEMBL	A0A0R4J424	1e-120	A0A0R4J424_SOYBN; Uncharacterized protein
STRING	GLYMA09G10010.1	1e-121	(Glycine max)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF4027	33	61

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G20380.7	3e-68	LSD family protein

Publications ? help Back to Top
Spedaletti V, et al. Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana. Biochemistry, 2008. 47(17): p. 4936-47 [PMID:18393445] Qi X, et al. Identification of a novel salt tolerance gene in wild soybean by whole-genome sequencing. Nat Commun, 2014. 5: p. 4340 [PMID:25004933] Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties. Plant Cell Rep., 2016. 35(3): p. 527-39 [PMID:26754794] Czarnocka W, et al. The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator. Plant Cell Environ., 2017. 40(11): p. 2644-2662 [PMID:28555890] Bernacki MJ, et al. LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana. Physiol Plant, 2019. 165(2): p. 369-382 [PMID:30461017]