PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KHN07734.1
Organism
Glycine soja
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family bHLH
Protein Properties Length: 430aa    MW: 48966.1 Da    PI: 5.3231
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KHN07734.1genomeTCUHKView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH383.1e-12223274155
                 CHHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
         HLH   1 rrrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 
                 +r++h ++Er+RR+++N+ +  Lr+l+P +   + ++ + a+i   A+e++++L+
  KHN07734.1 223 QRMTHIAVERNRRKQMNEHLRVLRSLMPGS---YVQRGDQASIIGGAIEFVRELE 274
                 79****************************...9*****************9995 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:4.10.280.101.5E-13221277IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.62E-12221278No hitNo description
SuperFamilySSF474592.36E-16222288IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088815.428222273IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000101.4E-9223274IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.4E-9228279IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd048730.00438356420No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010377Biological Processguard cell fate commitment
GO:0045597Biological Processpositive regulation of cell differentiation
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051782Biological Processnegative regulation of cell division
GO:0055114Biological Processoxidation-reduction process
GO:0005634Cellular Componentnucleus
GO:0032440Molecular Function2-alkenal reductase [NAD(P)] activity
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 430 aa     Download sequence    Send to blast
MPPSFNTLDY SLDQQQHHHL YAPNQHQQHL MMKFQQGSGD ENNNIGSMVD YMPQTTTTLP  60
PHGFYGTATS AATTSYDKLS FADVMQFADF GPKLALNQAK SCEESAIDPV YFLKFPVLND  120
KMEEDHQQNM MVNNDDPDGD EAENHHHLDE RFNLVSVEGK DQGMMMREDE ETTRVSDDNN  180
NSVQIRFLGH EEPQQKNCAV QENKNGKKKR PRTVKTSEEV ESQRMTHIAV ERNRRKQMNE  240
HLRVLRSLMP GSYVQRGDQA SIIGGAIEFV RELEQLLQCL ESQKRRRLLG EAQARQVGDP  300
SLVAQQQQQP PFFPTLPIPN EQMKLVEMET GLREETAECK SCLADVEVKL LGFDAMIKIL  360
SRRRPGQLIK TIAALEDLQL IILHTNITTI EQTVLYSFNV KVASDSRFTA EDIASSVQQI  420
FNFIHANTSM
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1223234RMTHIAVERNRR
2283287KRRRL
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator (PubMed:17088607, PubMed:17183265, PubMed:17183267). Together with MYB88 and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Together with SPCH and MUTE, regulates the stomata formation. Required to promote differentiation and morphogenesis of stomatal guard cells and to halt proliferative divisions in their immediate precursors. Mediates the formation of stomata (PubMed:17088607, PubMed:17183265, PubMed:17183267). Prevents histone H3K27me3 marks and derepresses stem cell gene expression (PubMed:24654956). {ECO:0000269|PubMed:17088607, ECO:0000269|PubMed:17183265, ECO:0000269|PubMed:17183267, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24654956}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKHN07734.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Inhibited by low relative humidity (LRH) via epigenetic CG methylation, thus leading to a reduced stomatal index. {ECO:0000269|PubMed:22442411}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAP0150431e-171AP015043.1 Vigna angularis var. angularis DNA, chromosome 10, almost complete sequence, cultivar: Shumari.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_014622344.10.0transcription factor FAMA isoform X2
RefseqXP_028204563.10.0transcription factor FAMA-like isoform X2
SwissprotQ56YJ81e-145FAMA_ARATH; Transcription factor FAMA
TrEMBLA0A0B2PJ720.0A0A0B2PJ72_GLYSO; Transcription factor FAMA
STRINGGLYMA02G14290.20.0(Glycine max)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF104893340
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G24140.11e-134bHLH family protein
Publications ? help Back to Top
  1. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  2. Qi X, et al.
    Identification of a novel salt tolerance gene in wild soybean by whole-genome sequencing.
    Nat Commun, 2014. 5: p. 4340
    [PMID:25004933]
  3. Matos JL, et al.
    Irreversible fate commitment in the Arabidopsis stomatal lineage requires a FAMA and RETINOBLASTOMA-RELATED module.
    Elife, 2015.
    [PMID:25303364]
  4. Chen L, et al.
    NRPB3, the third largest subunit of RNA polymerase II, is essential for stomatal patterning and differentiation in Arabidopsis.
    Development, 2016. 143(9): p. 1600-11
    [PMID:26989174]
  5. Lee JH,Jung JH,Park CM
    Light Inhibits COP1-Mediated Degradation of ICE Transcription Factors to Induce Stomatal Development in Arabidopsis.
    Plant Cell, 2017. 29(11): p. 2817-2830
    [PMID:29070509]
  6. Han X, et al.
    Jasmonate Negatively Regulates Stomatal Development in Arabidopsis Cotyledons.
    Plant Physiol., 2018. 176(4): p. 2871-2885
    [PMID:29496884]
  7. Li X,Yang R,Chen H
    The Arabidopsis thaliana Mediator subunit MED8 regulates plant immunity to Botrytis Cinerea through interacting with the basic helix-loop-helix (bHLH) transcription factor FAMA.
    PLoS ONE, 2018. 13(3): p. e0193458
    [PMID:29513733]