PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | KHM99167.1 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
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Family | bHLH | ||||||||
Protein Properties | Length: 218aa MW: 24469.2 Da PI: 9.9433 | ||||||||
Description | bHLH family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | HLH | 41.4 | 2.6e-13 | 32 | 77 | 4 | 54 |
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +h e+Er+RR+++N++f Lr ++P+ K++Ka+ L A+ YI++L KHM99167.1 32 NHVEAERQRREKLNQRFYALRAVVPNV-----SKMDKASLLGDAISYINEL 77 799***********************6.....5****************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
PROSITE profile | PS50888 | 17.39 | 28 | 77 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SuperFamily | SSF47459 | 6.94E-19 | 31 | 97 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
CDD | cd00083 | 1.53E-11 | 31 | 81 | No hit | No description |
Gene3D | G3DSA:4.10.280.10 | 6.1E-19 | 32 | 97 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Pfam | PF00010 | 8.4E-11 | 32 | 77 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
SMART | SM00353 | 1.9E-15 | 34 | 83 | IPR011598 | Myc-type, basic helix-loop-helix (bHLH) domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0055114 | Biological Process | oxidation-reduction process | ||||
GO:0032440 | Molecular Function | 2-alkenal reductase [NAD(P)] activity | ||||
GO:0046983 | Molecular Function | protein dimerization activity |
Sequence ? help Back to Top |
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Protein Sequence Length: 218 aa Download sequence Send to blast |
MVKQADSRVM EPEKRPRKRG RKPANGREEP LNHVEAERQR REKLNQRFYA LRAVVPNVSK 60 MDKASLLGDA ISYINELKLK LNGLDSEKGE LEKQLDSAKK ELELATKNPP PPPPPPPGLP 120 PSNNEEAKKT TTKLADLEIE VKIIGWDAMI RIQCSKKNHP AARLMAALKD LDLEVHHASV 180 SVVNDLMIQQ ATVNMGNKFY TQEQLLSALS SKVGDEQR |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
5gnj_A | 6e-35 | 26 | 102 | 2 | 78 | Transcription factor MYC2 |
5gnj_B | 6e-35 | 26 | 102 | 2 | 78 | Transcription factor MYC2 |
5gnj_E | 6e-35 | 26 | 102 | 2 | 78 | Transcription factor MYC2 |
5gnj_F | 6e-35 | 26 | 102 | 2 | 78 | Transcription factor MYC2 |
5gnj_G | 6e-35 | 26 | 102 | 2 | 78 | Transcription factor MYC2 |
5gnj_I | 6e-35 | 26 | 102 | 2 | 78 | Transcription factor MYC2 |
5gnj_M | 6e-35 | 26 | 102 | 2 | 78 | Transcription factor MYC2 |
5gnj_N | 6e-35 | 26 | 102 | 2 | 78 | Transcription factor MYC2 |
Search in ModeBase |
Nucleic Localization Signal ? help Back to Top | |||
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No. | Start | End | Sequence |
1 | 13 | 21 | KRPRKRGRK |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcriptional activator that binds to the G-box motif (5'-AACGTG-3') found in the promoter of the jasmonate-induced gene LAPA1 (PubMed:15231736). Acts as negative regulator of blue light-mediated photomorphogenesis and positively regulates root growth (PubMed:24483714). Promotes growth in response to the phytohormones abscisic acid (ABA) and jasmonate (JA) (PubMed:24483714). Binds to the G-box motif (5'-CACGTG-3') of the RBCS-3A gene promoter (PubMed:24483714). Acts downstream of the jasmonate (JA) receptor to orchestrate JA-mediated activation of plant responses (PubMed:28733419). Positively regulates both wound-responsive and pathogen-responsive genes through MYC2-targeted transcription factors (MTFs) involved in early response to JA (PubMed:28733419). With JA2L forms a transcription module that regulates wounding-responsive genes (PubMed:28733419). With ERF.C3 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). Plays a critical role in orchestrating JA-mediated defense gene expression during Botrytis cinerea infection (PubMed:28733419). Regulates negatively defense responses to root-knot nematodes, potentially by mediating crosstalk among the hormones strigolactones, abscisic acid (ABA) and jasmonate (JA) (PubMed:30576511). Regulates the termination of JA-mediated defense responses by specifically binding the G-box (5'-CACATG-3') motifs in the promoters of MTB1, MTB2 and MTB3, which are transcription factors that negatively regulates JA signaling (PubMed:30610166). May be involved in JA-induced chilling tolerance, possibly by ameliorating the antioxidant enzyme system of fruit and increasing proline and lycopene levels (PubMed:29528226). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:24483714, ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:29528226, ECO:0000269|PubMed:30576511, ECO:0000269|PubMed:30610166}. |
Cis-element ? help Back to Top | |
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Source | Link |
PlantRegMap | KHM99167.1 |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Induced by methyl jasmonate (PubMed:15231736, PubMed:28733419). Induced by wounding (PubMed:15231736). Induced by infection with the fungal pathogen Botrytis cinerea (PubMed:28733419). Induced in fruit by storage in cold (PubMed:29528226). Induced by hydrogen peroxide and infection with root-knot nematodes (PubMed:30576511). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:29528226, ECO:0000269|PubMed:30576511}. |
Regulation -- PlantRegMap ? help Back to Top | ||||||
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Source | Upstream Regulator | Target Gene | ||||
PlantRegMap | Retrieve | - |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_003516794.1 | 1e-154 | transcription factor MYC2 | ||||
Refseq | XP_028234627.1 | 1e-154 | transcription factor MYC2-like | ||||
Swissprot | A0A3Q7HRZ6 | 1e-93 | MYC2_SOLLC; Transcription factor MYC2 | ||||
TrEMBL | A0A0B2NVA1 | 1e-157 | A0A0B2NVA1_GLYSO; Transcription factor MYC4 | ||||
TrEMBL | A0A445M100 | 1e-153 | A0A445M100_GLYSO; Transcription factor MYC2 | ||||
TrEMBL | I1J6C6 | 1e-153 | I1J6C6_SOYBN; Uncharacterized protein | ||||
STRING | GLYMA01G12740.1 | 1e-154 | (Glycine max) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Fabids | OGEF2938 | 33 | 64 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT4G17880.1 | 2e-80 | bHLH family protein |