PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gorai.011G005300.1
Common NameB456_011G005300
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family LSD
Protein Properties Length: 175aa    MW: 18238.2 Da    PI: 8.2798
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gorai.011G005300.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD139.21.1e-121135125
             zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                        C+gCr  L YPrGA++V+CalC+tV
  Gorai.011G005300.1 11 CSGCRSNLLYPRGATNVCCALCNTV 35
                        ************************9 PP

2zf-LSD1391.3e-125073124
             zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdt 24
                        CggCrtlL+Y rG +sVRC++C+t
  Gorai.011G005300.1 50 CGGCRTLLMYARGGTSVRCSCCHT 73
                        ***********************8 PP

3zf-LSD1499.9e-1688112125
             zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdtV 25 
                         Cg+Crt+L+YP+GApsV+Ca+C+ V
  Gorai.011G005300.1  88 CGHCRTTLMYPYGAPSVKCAICQYV 112
                         ***********************87 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010539.5E-13838IPR005735Zinc finger, LSD1-type
PfamPF069432.1E-101135IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010535.9E-154776IPR005735Zinc finger, LSD1-type
PfamPF069432.5E-105073IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010534.0E-1385115IPR005735Zinc finger, LSD1-type
PfamPF069432.5E-1488112IPR005735Zinc finger, LSD1-type
Sequence ? help Back to Top
Protein Sequence    Length: 175 aa     Download sequence    Send to blast
MIADMQSQIV CSGCRSNLLY PRGATNVCCA LCNTVTQVPL PGMDMGQLIC GGCRTLLMYA  60
RGGTSVRCSC CHTLNLAPAP NQIAHINCGH CRTTLMYPYG APSVKCAICQ YVTNVGTGNA  120
RAPFCVSRPN QIASAGTVPS TSTSQTVVVE NPMSVDESGK LVSNVVVGIT TDKK*
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in cotyledons, roots, rosette leaves, stems, inflorescences and flowers. {ECO:0000269|PubMed:20456049}.
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012454254.11e-121PREDICTED: protein LSD1-like
RefseqXP_012454255.11e-121PREDICTED: protein LSD1-like
SwissprotP940772e-72LSD1_ARATH; Protein LSD1
TrEMBLA0A0D2VGH51e-123A0A0D2VGH5_GOSRA; Uncharacterized protein
STRINGGorai.011G005300.11e-123(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM53452650
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.71e-71LSD family protein
Publications ? help Back to Top
  1. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
    [PMID:18393445]
  2. Paterson AH, et al.
    Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres.
    Nature, 2012. 492(7429): p. 423-7
    [PMID:23257886]
  3. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
    [PMID:26754794]
  4. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
    [PMID:28555890]
  5. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382
    [PMID:30461017]