PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gorai.010G236100.1

Common Name

B456_010G236100, LOC105772948

Organism

Gossypium raimondii

Taxonomic ID

29730

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ERF

Protein Properties

Length: 397aa MW: 43894.3 Da PI: 4.6621

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gorai.010G236100.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	62.1	1.3e-19	123	172	2	55
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 +y+G+r+++ +g+W+AeIrdp++ r++lg+f taeeAa+a++a +++++g Gorai.010G236100.1 123 QYRGIRQRP-WGKWAAEIRDPRK---GVRVWLGTFNTAEEAARAYDAEALRIRG 172 69*****.******954...4***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	2.05E-33	123	181	No hit	No description
PROSITE profile	PS51032	24.553	123	180	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.63E-22	123	182	IPR016177	DNA-binding domain
SMART	SM00380	1.9E-37	123	186	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.2E-32	123	182	IPR001471	AP2/ERF domain
Pfam	PF00847	2.2E-12	124	172	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.2E-11	124	135	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.2E-11	146	162	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 397 aa Download sequence Send to blast
MCGGAIISDF IPPARSRLVT ANYLWPDLKK SGSKKRSGRK HSKKPAVGFE DDFEADFQVF 60 KDEDSDVDDF DDDVDDVLAD VKSFAFSATE KPSPAVSHGS NSIKSVEFNG QAEKSAKRKR 120 KNQYRGIRQR PWGKWAAEIR DPRKGVRVWL GTFNTAEEAA RAYDAEALRI RGKKAKVNFP 180 DETPRTSPKN AAKMNSQKPL SGSNLSSVQS SLNPDFSYSN KHEQGYYDTM GFIEEKSLMD 240 QFAYADPVRA AVDDGLKPFA EPENSASYFN SDQGSNNFDS SDLVWGEQGA KTPEISSSLG 300 PTLEVHEFLD NANPTKKLKP SSNNVMPTGG DNMVKSLSDE LLAMDNHVNY FQTPFIDENW 360 DVSIDDFLNG DATQDGGNEM GFWSFDDFPS IDGGVF*

Sequence ? help Back to Top

Protein Sequence Length: 397 aa Download sequence Send to blast

MCGGAIISDF IPPARSRLVT ANYLWPDLKK SGSKKRSGRK HSKKPAVGFE DDFEADFQVF  60
KDEDSDVDDF DDDVDDVLAD VKSFAFSATE KPSPAVSHGS NSIKSVEFNG QAEKSAKRKR  120
KNQYRGIRQR PWGKWAAEIR DPRKGVRVWL GTFNTAEEAA RAYDAEALRI RGKKAKVNFP  180
DETPRTSPKN AAKMNSQKPL SGSNLSSVQS SLNPDFSYSN KHEQGYYDTM GFIEEKSLMD  240
QFAYADPVRA AVDDGLKPFA EPENSASYFN SDQGSNNFDS SDLVWGEQGA KTPEISSSLG  300
PTLEVHEFLD NANPTKKLKP SSNNVMPTGG DNMVKSLSDE LLAMDNHVNY FQTPFIDENW  360
DVSIDDFLNG DATQDGGNEM GFWSFDDFPS IDGGVF*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	9e-22	123	180	2	60	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
5wx9_A	6e-21	122	182	13	74	Ethylene-responsive transcription factor ERF096
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Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Gra.2806	0.0	flower\|seedling\| flowering

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Highly expressed in seedlings, leaves, flowers, siliques and germinating seeds. {ECO:0000269\|PubMed:22020282}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the activation of hypoxic gene expression and in ethylene response. Partially redundant with RAP2-2. Acts as a downstream regulator in the ethylene signaling pathway. {ECO:0000269\|PubMed:22020282, ECO:0000269\|PubMed:22530619}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by hypoxia but not by ethylene. {ECO:0000269\|PubMed:22020282}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY817134	0.0	AY817134.1 Gossypium hirsutum putative ethylene responsive element binding protein mRNA, complete cds.
GenBank	KP780201	0.0	KP780201.1 Gossypium hirsutum C-repeat binding factor 18 (CBF18) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012449927.1	0.0	PREDICTED: ethylene-responsive transcription factor RAP2-12-like
Swissprot	Q9SSA8	1e-82	RA212_ARATH; Ethylene-responsive transcription factor RAP2-12
TrEMBL	A0A0D2VEF2	0.0	A0A0D2VEF2_GOSRA; Uncharacterized protein
STRING	Gorai.010G236100.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G53910.3	7e-76	related to AP2 12

Link Out ? help Back to Top
Phytozome	Gorai.010G236100.1
Entrez Gene	105772948

Publications ? help Back to Top
Paterson AH, et al. Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres. Nature, 2012. 492(7429): p. 423-7 [PMID:23257886] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Kosmacz M, et al. The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration. Plant Cell Environ., 2015. 38(6): p. 1094-103 [PMID:25438831] Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana. Plant Sci., 2015. 236: p. 37-43 [PMID:26025519] Gasch P, et al. Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis. Plant Cell, 2016. 28(1): p. 160-80 [PMID:26668304] Gonzali S, et al. Universal stress protein HRU1 mediates ROS homeostasis under anoxia. Nat Plants, 2015. 1: p. 15151 [PMID:27251529] Paul MV, et al. Oxygen Sensing via the Ethylene Response Transcription Factor RAP2.12 Affects Plant Metabolism and Performance under Both Normoxia and Hypoxia. Plant Physiol., 2016. 172(1): p. 141-53 [PMID:27372243] Shahzad Z, et al. A Potassium-Dependent Oxygen Sensing Pathway Regulates Plant Root Hydraulics. Cell, 2016. 167(1): p. 87-98.e14 [PMID:27641502] Yao Y, et al. ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis. New Phytol., 2017. 213(4): p. 1667-1681 [PMID:28164334] Giuntoli B,Licausi F,van Veen H,Perata P Functional Balancing of the Hypoxia Regulators RAP2.12 and HRA1 Takes Place in vivo in Arabidopsis thaliana Plants. Front Plant Sci, 2017. 8: p. 591 [PMID:28487707] Yao Y,Chen X,Wu AM ERF-VII members exhibit synergistic and separate roles in Arabidopsis. Plant Signal Behav, 2017. 12(6): p. e1329073 [PMID:28537474] Eysholdt-Derzsó E,Sauter M Root Bending Is Antagonistically Affected by Hypoxia and ERF-Mediated Transcription via Auxin Signaling. Plant Physiol., 2017. 175(1): p. 412-423 [PMID:28698356] Giuntoli B, et al. Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana. Plant Cell Environ., 2017. 40(10): p. 2333-2346 [PMID:28741696]