PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gorai.007G366600.2
Common NameB456_007G366600, LOC105761700
Organism
Gossypium raimondii
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family E2F/DP
Protein Properties Length: 480aa    MW: 52910.2 Da    PI: 4.7046
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gorai.007G366600.2genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP86.22.4e-27157222171
             E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                         r+++sL+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  Gorai.007G366600.2 157 RYDSSLGLLTKKFVNLMKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKFKNRIQWKG 222
                         6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.103.6E-29154223IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467855.03E-17157220IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.8E-35157222IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.8E-24159222IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440749.94E-34235339No hitNo description
CDDcd146604.52E-49235339No hitNo description
PfamPF164211.0E-33239337IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 480 aa     Download sequence    Send to blast
MSGGAGASDG PTLPYQPSPT ASTAPASTVP SVVPPIRRHL AFASTKPPFV HPDDYHRFSS  60
SNSRGIVADQ EVEAIVVRFP QLKRKSAADK NEVESSQWTS SPGVTSISNS PFQTPVSAKG  120
GRIDNRSKTS KANKSMPQTP VSNAGCPSPL TPAGSCRYDS SLGLLTKKFV NLMKHAEDGI  180
LDLNKAAETL EVQKRRIYDI TNVLEGIGLI EKKFKNRIQW KGVGASKPGE TDGDVSVIQE  240
EIENLSMEER RLDDQIREMQ ERLRDLSENE NNQKLLFVTE EDIKGIPCFQ NETLIAIKAP  300
HGTTLEVPDP DEDVDYRQRR YRIILRSTMG PIDVYLVSQF EEKFEEMNGV EPPLRVPLAS  360
SSGSNENQVE LVNTVSIQKE IELQAQQTHQ ICSDINATQE SVGGMMRIVP SDIDNDADYW  420
LLSDADVSIT DMWKTDCVEW SGVDMLHSDF GMAEVGTPRP ESPPSRMTEV PSSDFKSTR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-25152224275PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}.
UniprotTISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012435055.10.0PREDICTED: transcription factor E2FA-like
SwissprotQ9FNY01e-177E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A0D2SQG10.0A0A0D2SQG1_GOSRA; Uncharacterized protein
STRINGGorai.007G366600.10.0(Gossypium raimondii)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-178E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]
  2. Paterson AH, et al.
    Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres.
    Nature, 2012. 492(7429): p. 423-7
    [PMID:23257886]