PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gorai.007G226500.1
Common NameB456_007G226500, LOC105804066
Organism
Gossypium raimondii
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family AP2
Protein Properties Length: 681aa    MW: 75495.4 Da    PI: 7.0491
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gorai.007G226500.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP250.93.9e-16327386155
                 AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 
                         s+y+GV++++++gr++A+++d  ++  g  ++ ++++lg ++ +e+Aa+a++ a++k++g
  Gorai.007G226500.1 327 SQYRGVTRHRWTGRYEAHLWDnSCKkEGqsRKgRQVYLGGYDMEEKAARAYDLAALKYWG 386
                         78*******************988886678446*************************98 PP
2AP246.41e-14431480355
                 AP2   3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                         y+GV+++++ grW A+I  +     +k  +lg+f t eeAa+a++ a+ k++g
  Gorai.007G226500.1 431 YRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSTQEEAAEAYDIAAIKFRG 480
                         9***************988532...5*************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000182.10E-21327394No hitNo description
PfamPF008476.8E-13327386IPR001471AP2/ERF domain
SuperFamilySSF541711.11E-16327396IPR016177DNA-binding domain
SMARTSM003802.6E-29328400IPR001471AP2/ERF domain
PROSITE profilePS5103219.203328394IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.104.6E-16328395IPR001471AP2/ERF domain
PRINTSPR003672.6E-6329340IPR001471AP2/ERF domain
CDDcd000181.92E-24429490No hitNo description
SuperFamilySSF541711.57E-17429489IPR016177DNA-binding domain
SMARTSM003803.7E-33430494IPR001471AP2/ERF domain
PROSITE profilePS5103219.19430488IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.6E-18430488IPR001471AP2/ERF domain
PfamPF008471.8E-9431480IPR001471AP2/ERF domain
PRINTSPR003672.6E-6470490IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 681 aa     Download sequence    Send to blast
MKSMSNDDNN NNNNNSSNWL GFSLSSHMKM EVSNQGPNSN HKTQSAASGV TTAVPSSFFP  60
SPPSHLNYGL YFGVEGENGG LYSHFPVMPL KSDGSLCLME ALGRSQSQAM VPTSTPKLED  120
FFGGATMGTH HYESSDRETM ALSLDSMYYH QNPNQDHNSQ NCLDHLQHSS RQQHHQHQLQ  180
VQQYQYYSGY RNQEMLLAEE ADQETHVTDC NLQLPTMADD GSAAMKHWAS RNYSTEHSAM  240
NQKMIGCMGD NGADSGSIGA MAYGDLQSLS LSMSPGSQSS SVAGSQQISP SATDYAAMET  300
KKRGSEKVDQ KQIAHRKSID TFGQRTSQYR GVTRHRWTGR YEAHLWDNSC KKEGQSRKGR  360
QVYLGGYDME EKAARAYDLA ALKYWGPSTH INFPLENYQK ELEEMKNMTR QEYVAHLRRK  420
SSGFSRGASM YRGVTRHHQH GRWQARIGRV AGNKDLYLGT FSTQEEAAEA YDIAAIKFRG  480
ANAVTNFDIT RYDVERIMAS STLLAGDLAR RNKDIGPANE AINHNLLAHN SYGETNISPK  540
NNGSQPDWKI VLHQSPEQQM EMKQANMIEN YKRQDFSLAP DNLVGMDTIN SGQREVDDSN  600
KMGTHFSNAS SLLTSLSSST QGSSGSLDRN SLPLPFAMPA PPTKLFTSST NSLNSWIPSA  660
QLRPALTVPT VPVFTAWTDA *
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Gra.16811e-167flower| flowering
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO488125421e-167
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in floral primordia, in STM-negative region, then in sepal primordia. As sepal develops, progressively confined to a basal core before disappearing. Present in stamen primordia, then confined to a central region as they become stalked and develop locules. Later reduced to procambial cells as stamen mature. From petal primordia, expressed on the lateral edges of developing petals and finally confined to petal epidermis before disappearing. Present in carpel primordia, then in inner side of carpels especially in the placenta. Strong levels in ovules primordia and young ovules, then localized in integuments initiation zone before being confined to inner integument cells that will differentiate into the endothelium. Expressed in the distal half of the funiculus throughout ovule development and later extends into the chalaza. After fertilization, expression shift to the embryo. First on the apical part at the globular stage, then in cotyledons primordia, and later in cotyledons during the torpedo stage. As cotyledons grow out, expression becomes limited to a plane separating adaxial and abaxial parts. Excluded from the embryonic central region (ECR). In seedlings, found in leaf primordia then in central and lateral actively developing regions of extending leaves. {ECO:0000269|PubMed:10656774, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9671577}.
UniprotTISSUE SPECIFICITY: Highly expressed at the base of the stem. Expressed in stems. Expressed a low levels in crown roots and seeds (PubMed:21807632). Expressed in the stem region where adventitious (crown) root initiation occurs (PubMed:21481033). {ECO:0000269|PubMed:21481033, ECO:0000269|PubMed:21807632}.
UniprotTISSUE SPECIFICITY: Mostly expressed in developing flowers. Also present in mature flowers, siliques and seedlings, but not in mature roots, leaves and stems. Expressed in ovules and in vegetative and floral primordia. {ECO:0000269|PubMed:15988559, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707}.
Functional Description ? help Back to Top
Source Description
UniProtActs as positive regulator of adventitious (crown) root formation by promoting its initiation. Promotes adventitious root initiation through repression of cytokinin signaling by positively regulating the two-component response regulator RR1. Regulated by the auxin response factor and transcriptional activator ARF23/ARF1. {ECO:0000269|PubMed:21481033}.
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by auxin. {ECO:0000269|PubMed:21481033}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012492017.10.0PREDICTED: AP2-like ethylene-responsive transcription factor ANT
SwissprotQ389141e-142ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
SwissprotQ84Z021e-141CRL5_ORYSJ; AP2-like ethylene-responsive transcription factor CRL5
TrEMBLA0A0D2PDP20.0A0A0D2PDP2_GOSRA; Uncharacterized protein
STRINGGorai.007G226500.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM31372863
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.11e-132AP2 family protein
Publications ? help Back to Top
  1. Kitomi Y, et al.
    The auxin responsive AP2/ERF transcription factor CROWN ROOTLESS5 is involved in crown root initiation in rice through the induction of OsRR1, a type-A response regulator of cytokinin signaling.
    Plant J., 2011. 67(3): p. 472-84
    [PMID:21481033]
  2. Li P,Xue H
    Structural characterization and expression pattern analysis of the rice PLT gene family.
    Acta Biochim. Biophys. Sin. (Shanghai), 2011. 43(9): p. 688-97
    [PMID:21807632]
  3. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  4. Paterson AH, et al.
    Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres.
    Nature, 2012. 492(7429): p. 423-7
    [PMID:23257886]
  5. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  6. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  7. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  8. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  9. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  10. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  11. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  12. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  13. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  14. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]