PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gorai.002G157200.1
Common NameB456_002G157200, LOC105785460
Organism
Gossypium raimondii
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family E2F/DP
Protein Properties Length: 502aa    MW: 55507.4 Da    PI: 5.6754
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gorai.002G157200.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.86.9e-27168233171
             E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                         r+++sL+ lt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+irwkg
  Gorai.002G157200.1 168 RYDSSLGFLTKKFINLIKHAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNKIRWKG 233
                         6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.3E-28165235IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.24E-16168231IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013726.4E-34168233IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.7E-24170233IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440744.45E-32245349No hitNo description
CDDcd146603.33E-46245349No hitNo description
PfamPF164217.6E-32248347IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 502 aa     Download sequence    Send to blast
MSGVARASAC PTSPHPPPSM TAVSAPAPSA PSIVPPIRRH LAFASMKPPF VHPDDYHRFS  60
SNNSNNNLTT GNNTRGIIAD QEVEAIVVRS PKLKRKSTTV NKEVESSQWT TSPRVTSTAN  120
SPFQTPVSAK GGRINNRSKA SKANKSALQT PVSNASSPAP LTPAGSCRYD SSLGFLTKKF  180
INLIKHAEDG ILDLNKAAET LEVQKRRIYD ITNVLEGIGL IEKKLKNKIR WKGVDDSRPE  240
ADGDVSLLQA EIENLTMKEH TLDDQIREMQ ERLRDLSENE NNQRWLFVTE EDIKGLPCFR  300
NETLIAIKAP HGTTLEVPDP DEAVDYPQRR YRMILRSTMG SIDVYLVSQF EKFEEVNGVE  360
PPASVSLASS SGSNENQVEL VNVERTRKEI EPQAVQTHQM DCDVNASQES VGGMMRIVPS  420
DIDNDADYWL LSDADVSITD MWKTDCVEWS GVDMLDANFG MADISTPRPQ SPPSRMVEVP  480
SHAFHSTHRR MQFSVVEQIM G*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-23163234274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Most abundant in early S phase. Decreased expression during the passage into G2. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543}.
UniprotTISSUE SPECIFICITY: Highly expressed in the shoot apical meristem, emerging leaf primordia, and vascular tissues of young leaf primordia. Expressed in flowers, in epidermis and cortex of hypocotyls, and at lower levels in leaves. {ECO:0000269|PubMed:11108847, ECO:0000269|PubMed:11889041}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012467009.10.0PREDICTED: transcription factor E2FA-like isoform X1
SwissprotQ9FNY01e-175E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A0D2Q7820.0A0A0D2Q782_GOSRA; Uncharacterized protein
STRINGGorai.002G157200.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM80828121
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.11e-167E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]
  2. Paterson AH, et al.
    Repeated polyploidization of Gossypium genomes and the evolution of spinnable cotton fibres.
    Nature, 2012. 492(7429): p. 423-7
    [PMID:23257886]