PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KXZ54938.1
Organism
Gonium pectorale
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Chlorophyta; Chlorophyceae; Chlamydomonadales; Volvocaceae; Gonium
Family E2F/DP
Protein Properties Length: 169aa    MW: 18725.2 Da    PI: 4.9257
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KXZ54938.1genomeGPGRPView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP78.37.1e-25159871
     E2F_TDP  8 lltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                +lt+kfl+l+ ++e+g+++ln++a++L   +v  ++RRiYDi+NVLe+++liekk+kn+irwkg
  KXZ54938.1  1 MLTKKFLTLIDNAEDGVLDLNKAAETL---KV--QKRRIYDITNVLEGVGLIEKKSKNNIRWKG 59
                59*************************...88..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF023191.7E-22159IPR003316E2F/DP family, winged-helix DNA-binding domain
SMARTSM013723.4E-26159IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467856.46E-16260IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.104.6E-25260IPR011991Winged helix-turn-helix DNA-binding domain
CDDcd146602.39E-3171149No hitNo description
SuperFamilySSF1440744.45E-2271149No hitNo description
PfamPF164216.9E-2075149IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0042023Biological ProcessDNA endoreduplication
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0051782Biological Processnegative regulation of cell division
GO:0005667Cellular Componenttranscription factor complex
GO:0005730Cellular Componentnucleolus
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 169 aa     Download sequence    Send to blast
MLTKKFLTLI DNAEDGVLDL NKAAETLKVQ KRRIYDITNV LEGVGLIEKK SKNNIRWKGA  60
GGGDGRESEP EVSRLRMDIR SLEDQERSLD EHIRIMSGVI QSITDNPINK NRLYVTDEDV  120
TALPAFASDT IFAVKAPPGT TLEVPDPREA ADPRDGGLRY SPAFLNAFA
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A8e-241611475PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
12632LKVQKRR
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00190DAPTransfer from AT1G47870Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMap-Retrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002948442.12e-92E2F transcription factor family
SwissprotQ9FNY01e-46E2FA_ARATH; Transcription factor E2FA
TrEMBLA0A150GZ331e-119A0A150GZ33_GONPE; E2F1 protein
STRINGXP_002948442.18e-92(Volvox carteri)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
ChlorophytaeOGCP32581314
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.18e-50E2F transcription factor 3
Publications ? help Back to Top
  1. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]