PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Glyma.06G024900.3.p
Common NameGLYMA_06G024900
Organism
Glycine max
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family E2F/DP
Protein Properties Length: 340aa    MW: 38363.9 Da    PI: 4.6773
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Glyma.06G024900.3.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.21e-2670135171
              E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                          r+++sL+llt+kf++l++ +++g+++ln  a+ L   +v  ++RRiYDi+NVLe+++liek++kn+i+wkg
  Glyma.06G024900.3.p  70 RYDSSLGLLTKKFVSLIQDAKDGTLDLNRTAEIL---EV--QKRRIYDITNVLEGVGLIEKTSKNHIQWKG 135
                          6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.109.0E-2967136IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.1E-3570135IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467859.07E-1870133IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023195.4E-2572135IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440741.36E-26146253No hitNo description
CDDcd146607.38E-35146253No hitNo description
PfamPF164219.5E-26151250IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000902Biological Processcell morphogenesis
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0051782Biological Processnegative regulation of cell division
GO:0005667Cellular Componenttranscription factor complex
GO:0005730Cellular Componentnucleolus
GO:0016021Cellular Componentintegral component of membrane
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 340 aa     Download sequence    Send to blast
MSQRYDNNVF KSHINNIQLA PGITETLHLP PPLQTEPTIR GKQNGKSKGP RNAKSANADS  60
PNSTAVNNCR YDSSLGLLTK KFVSLIQDAK DGTLDLNRTA EILEVQKRRI YDITNVLEGV  120
GLIEKTSKNH IQWKGCDGLG PQELEDQVNS LKAEVDSLYA EESELDDCIR KKQELLRNLE  180
ESESSQKYLF LTKEDILSLP CFQNQEIIAI KAPKASCIEV PDPDEELGFR QRQYKMIVRS  240
AIGPINLYLL SKDDSKFEDD SAKRMKLMDP SWNSDPIRKR GVGLLESQHD EKNPSEHFSL  300
QGSQAFGIQE ITPTDFEMED DYWFQSDPGV SQTELWGNE*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A2e-2569136674PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected at the G1/S transition, but increases during the progression into S phase and peaks after the passage into G2. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:12468727}.
UniprotTISSUE SPECIFICITY: Expressed in meristematic areas, vascular tissues, apical part of the roots, cotyledons, upper region of the hypocotyls, trichomes, young flower buds and pollen grains. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782}.
Functional Description ? help Back to Top
Source Description
UniProtInvolved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00190DAPTransfer from AT1G47870Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapGlyma.06G024900.3.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0970030.0BT097003.1 Soybean clone JCVI-FLGm-15J6 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006581173.10.0transcription factor E2FC isoform X3
RefseqXP_025984597.10.0transcription factor E2FC isoform X1
RefseqXP_025984599.10.0transcription factor E2FC isoform X3
RefseqXP_025984600.10.0transcription factor E2FC isoform X3
RefseqXP_028234704.10.0transcription factor E2FC-like isoform X1
SwissprotQ9FV709e-92E2FC_ARATH; Transcription factor E2FC
TrEMBLA0A0R0JKL10.0A0A0R0JKL1_SOYBN; Uncharacterized protein
TrEMBLK7KSN50.0K7KSN5_SOYBN; Uncharacterized protein
STRINGGLYMA06G02738.10.0(Glycine max)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G47870.26e-92E2F/DP family protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  2. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  3. Huntley R, et al.
    The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins.
    Plant Mol. Biol., 1998. 37(1): p. 155-69
    [PMID:9620273]