PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Glyma.06G024900.2.p
Common NameGLYMA_06G024900
Organism
Glycine max
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family E2F/DP
Protein Properties Length: 424aa    MW: 47839.3 Da    PI: 6.4176
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Glyma.06G024900.2.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP83.71.4e-26157222171
              E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                          r+++sL+llt+kf++l++ +++g+++ln  a+ L   +v  ++RRiYDi+NVLe+++liek++kn+i+wkg
  Glyma.06G024900.2.p 157 RYDSSLGLLTKKFVSLIQDAKDGTLDLNRTAEIL---EV--QKRRIYDITNVLEGVGLIEKTSKNHIQWKG 222
                          6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.3E-28154223IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467851.9E-17157220IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.1E-35157222IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023197.6E-25159222IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd146603.44E-35233340No hitNo description
SuperFamilySSF1440742.07E-26233340No hitNo description
PfamPF164211.4E-25238337IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000902Biological Processcell morphogenesis
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0051782Biological Processnegative regulation of cell division
GO:0005667Cellular Componenttranscription factor complex
GO:0005730Cellular Componentnucleolus
GO:0016021Cellular Componentintegral component of membrane
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 424 aa     Download sequence    Send to blast
MVYVREAQKG AQKVRPKRKR KGRGGVCIRT ELTAFFALVL AATPYQTFTF TSLFSFLLLY  60
ITVLLFHTQT LSLVSSISLQ IHSPFPNMSQ RYDNNVFKSH INNIQLAPGI TETLHLPPPL  120
QTEPTIRGKQ NGKSKGPRNA KSANADSPNS TAVNNCRYDS SLGLLTKKFV SLIQDAKDGT  180
LDLNRTAEIL EVQKRRIYDI TNVLEGVGLI EKTSKNHIQW KGCDGLGPQE LEDQVNSLKA  240
EVDSLYAEES ELDDCIRKKQ ELLRNLEESE SSQKYLFLTK EDILSLPCFQ NQEIIAIKAP  300
KASCIEVPDP DEELGFRQRQ YKMIVRSAIG PINLYLLSKD DSKFEDDSAK RMKLMDPSWN  360
SDPIRKRGVG LLESQHDEKN PSEHFSLQGS QAFGIQEITP TDFEMEDDYW FQSDPGVSQT  420
ELK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A5e-25156223674PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected at the G1/S transition, but increases during the progression into S phase and peaks after the passage into G2. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:12468727}.
UniprotTISSUE SPECIFICITY: Expressed in meristematic areas, vascular tissues, apical part of the roots, cotyledons, upper region of the hypocotyls, trichomes, young flower buds and pollen grains. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782}.
Functional Description ? help Back to Top
Source Description
UniProtInvolved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00190DAPTransfer from AT1G47870Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapGlyma.06G024900.2.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0970030.0BT097003.1 Soybean clone JCVI-FLGm-15J6 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_025984598.10.0transcription factor E2FC isoform X2
SwissprotQ9FV703e-88E2FC_ARATH; Transcription factor E2FC
TrEMBLK7KSN60.0K7KSN6_SOYBN; Uncharacterized protein
STRINGGLYMA06G02738.10.0(Glycine max)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G47870.22e-88E2F/DP family protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  2. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  3. Huntley R, et al.
    The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins.
    Plant Mol. Biol., 1998. 37(1): p. 155-69
    [PMID:9620273]