PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Glyma.04G178300.2.p
Common NameGLYMA_04G178300
Organism
Glycine max
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family E2F/DP
Protein Properties Length: 243aa    MW: 28096.9 Da    PI: 10.2786
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Glyma.04G178300.2.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP70.42.1e-2211102171
              E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse..................dvknkrRRiYDilNVLealnliek.....keknei 67 
                          r+eksL lltq+f+kl+ +s+ ++++l+e+ak L+ +                      k+RR+YDi+NVL+++nliek     ++k+++
  Glyma.04G178300.2.p  11 RREKSLALLTQNFVKLFVCSNFEMISLDEAAKLLLGNannrtfnflslylydfylT--AKVRRLYDIANVLSSMNLIEKthttnTRKPAF 98 
                          689********************************99***************9543..599*********************999***** PP

              E2F_TDP  68 rwkg 71 
                          rw g
  Glyma.04G178300.2.p  99 RWLG 102
                          **87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.109.8E-247103IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013728.5E-2511102IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.7E-1713102IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.9E-1313103IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 243 aa     Download sequence    Send to blast
MVKSSSKNEN RREKSLALLT QNFVKLFVCS NFEMISLDEA AKLLLGNANN RTFNFLSLYL  60
YDFYLTAKVR RLYDIANVLS SMNLIEKTHT TNTRKPAFRW LGVRGKTWSE SAQTNVKESQ  120
KRMFGSDITN INFKRKVDLS MDGQNFKTQN QQENISPRAQ LEKKSLKKDA KQTSMSYQFG  180
PFAPAYVHKV GTSENNSVKQ VQDWESLAQE HRPQYQNQAL KDLFSHYMEA WKSWYSEAAK  240
TL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A3e-131094151228Transcription factor E2F8
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Gma.331890.0cotyledon| flower| stem
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected during early S phase. Expressed at both the G1/S and S/G2 transitions, with a peak during G2. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:18787127}.
UniprotTISSUE SPECIFICITY: Expressed exclusively in mitotically dividing cells. Highly expressed in young leaves and mature flowers. Lower expression in young stalk and in young and mature flowers. {ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366}.
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGlyma.04G178300.2.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006578607.11e-158E2F transcription factor-like E2FE isoform X5
RefseqXP_028229184.11e-158E2F transcription factor-like E2FE isoform X5
SwissprotQ8LSZ44e-66E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A0R0K9I51e-180A0A0R0K9I5_SOYBN; Uncharacterized protein
STRINGGLYMA04G34870.31e-163(Glycine max)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.22e-68DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]