PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Glyma.04G024800.3.p
Common NameGLYMA_04G024800
Organism
Glycine max
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja
Family E2F/DP
Protein Properties Length: 344aa    MW: 38851.6 Da    PI: 5.0953
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Glyma.04G024800.3.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP84.11.1e-2674139171
              E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                          r+++sL+llt+kf++l++ +++g+++ln  a+ L   +v  ++RRiYDi+NVLe+++liek++kn+i+wkg
  Glyma.04G024800.3.p  74 RYDSSLGLLTKKFVSLIQDAKDGTLDLNRTAEIL---EV--QKRRIYDITNVLEGVGLIEKTSKNHIKWKG 139
                          6899******************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.3E-2871140IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013725.4E-3574139IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.18E-1774137IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023196.6E-2576139IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440746.54E-26150257No hitNo description
CDDcd146605.22E-35150257No hitNo description
PfamPF164211.5E-24155254IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 344 aa     Download sequence    Send to blast
MGQRYENNVF KSHISNIEAA PGMTQTVHLP PPLQTDPTIR GKQNGKPKGS RNAKSAAHRP  60
YADSTNSTAV NNCRYDSSLG LLTKKFVSLI QDAKDGTLDL NRTAEILEVQ KRRIYDITNV  120
LEGVGLIEKT SKNHIKWKGC DGLGPRELED QVNSLKAEVD SLYAEECKLD DCIRKKQELL  180
RNLEESESSQ KYLFITKEDI LGLPCFQNQE IIAIKAPKAS SIEVPDPDEE LGFRQRQYKM  240
IVRSAIGPIY LYLLSKDDHK FEDDSAKPMK LTNPSWNSDL YRKRGVGLLE SQNDENNPSE  300
RFSLQGSQAF GIQEITPTDF EMEDDYWFQS DPGVSQTELW GKE*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A1e-2473140674PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in a cell cycle-dependent manner. Not detected at the G1/S transition, but increases during the progression into S phase and peaks after the passage into G2. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:12468727}.
UniprotTISSUE SPECIFICITY: Expressed in meristematic areas, vascular tissues, apical part of the roots, cotyledons, upper region of the hypocotyls, trichomes, young flower buds and pollen grains. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782}.
Functional Description ? help Back to Top
Source Description
UniProtInvolved in transcriptional repression. May act by repressing E2F-regulated genes in mature differentiated cells, but is not an antagonist of E2FA. Restricts cell division and is involved in the coordination between cell proliferation and endoreduplication during development. May play a role during the transition from skotomorphogenesis to photomorphogenesis. Regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(SKP2A) complex. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:16920782, ECO:0000269|PubMed:19662336}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapGlyma.04G024800.3.p
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by light. {ECO:0000269|PubMed:12468727, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0970030.0BT097003.1 Soybean clone JCVI-FLGm-15J6 unknown mRNA.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_014629912.10.0transcription factor E2FC isoform X3
RefseqXP_028227478.10.0transcription factor E2FC-like isoform X3
SwissprotQ9FV709e-90E2FC_ARATH; Transcription factor E2FC
TrEMBLA0A445KUI80.0A0A445KUI8_GLYSO; Transcription factor E2FC isoform C
TrEMBLI1JT390.0I1JT39_SOYBN; Uncharacterized protein
STRINGGLYMA04G02720.40.0(Glycine max)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G47870.26e-82E2F/DP family protein
Publications ? help Back to Top
  1. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]
  2. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]
  3. Huntley R, et al.
    The maize retinoblastoma protein homologue ZmRb-1 is regulated during leaf development and displays conserved interactions with G1/S regulators and plant cyclin D (CycD) proteins.
    Plant Mol. Biol., 1998. 37(1): p. 155-69
    [PMID:9620273]