PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_Sca049741G01
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family ERF
Protein Properties Length: 110aa    MW: 12556.2 Da    PI: 10.6212
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_Sca049741G01genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP252.61.2e-164392255
              AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                     +y GVr+++ +grWvAeI+  s   ++ r +lg+f+ +eeAa a+++a+  l+g
  Gh_Sca049741G01 43 RYLGVRQRP-SGRWVAEIKNSS---QKLRLWLGTFDQPEEAALAYDNAAMVLRG 92
                     689******.7******98832...46**********************99998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM003806.7E-3143106IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.108.5E-2843100IPR001471AP2/ERF domain
PROSITE profilePS5103219.80943100IPR001471AP2/ERF domain
PfamPF008473.8E-124392IPR001471AP2/ERF domain
CDDcd000188.66E-2943101No hitNo description
SuperFamilySSF541715.49E-2043101IPR016177DNA-binding domain
PRINTSPR003672.1E-74455IPR001471AP2/ERF domain
PRINTSPR003672.1E-76682IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 110 aa     Download sequence    Send to blast
MVPQQDQSPN KNQTSIEPHE AQTMAENSEK RSIKKVINNG RRRYLGVRQR PSGRWVAEIK  60
NSSQKLRLWL GTFDQPEEAA LAYDNAAMVL RGKNAKTNFQ YEGNLNLIGK
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A4e-15431061478Ethylene-responsive transcription factor ERF096
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in roots, root hairs and leaves (PubMed:17827349). Expressed in root epidermis and root hairs (PubMed:23077241). {ECO:0000269|PubMed:17827349, ECO:0000269|PubMed:23077241}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in symbiotic nodule signaling in response to rhizobial Nod factors (NFs) (PubMed:17449807, PubMed:17827349). Binds to the GCC-box (NF-responsive box) of ENOD11 promoter. Acts as transcriptional activator of NF-responsive box-containing target gene promoters in root hairs (PubMed:17827349). Functions as a transcriptional regulator required for root infection by symbiotic rhizobia, infection thread (IT) formation and maintenance, and nodule development. Necessary for NF-induced gene expression and spontaneous nodulation activated by CCAMK. Functions downstream of CCAMK to activate nodulation gene expression (PubMed:17449807). Involved in early stages of root nodule development. Functions redundantly with ERN2. Is essential with ERN2 for the initiation of root hair infection, and nodule organogenesis and development. Required for accurate expression of the NF signaling genes ENOD11 and ENOD12 (PubMed:23077241, PubMed:27208242). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349, ECO:0000269|PubMed:23077241, ECO:0000269|PubMed:27208242}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced in roots from 1 to 21 day after inoculation with Sinorhizobium meliloti (PubMed:17449807). Induced by Nod factors in root hairs (PubMed:17827349). {ECO:0000269|PubMed:17449807, ECO:0000269|PubMed:17827349}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016747650.11e-76PREDICTED: ethylene-responsive transcription factor ERF095-like
SwissprotA2Q5W14e-24ERN1_MEDTR; Ethylene-responsive transcription factor ERN1
TrEMBLA0A1U8P9292e-75A0A1U8P929_GOSHI; ethylene-responsive transcription factor ERF095-like
STRINGGorai.001G064900.11e-75(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM17770810
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G19790.11e-25related to AP2 11
Publications ? help Back to Top
  1. Cerri MR, et al.
    Medicago truncatula ERN transcription factors: regulatory interplay with NSP1/NSP2 GRAS factors and expression dynamics throughout rhizobial infection.
    Plant Physiol., 2012. 160(4): p. 2155-72
    [PMID:23077241]
  2. Tang H, et al.
    An improved genome release (version Mt4.0) for the model legume Medicago truncatula.
    BMC Genomics, 2014. 15: p. 312
    [PMID:24767513]
  3. Cerri MR, et al.
    The Symbiosis-Related ERN Transcription Factors Act in Concert to Coordinate Rhizobial Host Root Infection.
    Plant Physiol., 2016. 171(2): p. 1037-54
    [PMID:27208242]