PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_D13G1046

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

ERF

Protein Properties

Length: 273aa MW: 30181.4 Da PI: 6.2506

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_D13G1046	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	55.7	1.2e-17	38	87	2	55
AP2 2 gykGVrwdkkrgrWvAeIrd.psengkrkrfslgkfgtaeeAakaaiaarkkleg 55 ++ GVr+++ +grWvAeI+ ++ r +lg+f taeeAa+a+++a+ l+g Gh_D13G1046 38 KFVGVRQRP-SGRWVAEIKNtT----HKIRMWLGTFETAEEAARAYDEAACLLHG 87 799****.7**99922....34********************99998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00380	1.9E-34	38	101	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	19.388	38	95	IPR001471	AP2/ERF domain
Pfam	PF00847	7.1E-13	38	87	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	4.58E-19	38	95	IPR016177	DNA-binding domain
Gene3D	G3DSA:3.30.730.10	6.2E-27	38	95	IPR001471	AP2/ERF domain
CDD	cd00018	7.82E-31	38	94	No hit	No description
PRINTS	PR00367	9.2E-8	39	50	IPR001471	AP2/ERF domain
PRINTS	PR00367	9.2E-8	61	77	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 273 aa Download sequence Send to blast
MEIQSQQQIQ LKLQPKSSNP SVSKGSKFKG RNNNKVNKFV GVRQRPSGRW VAEIKNTTHK 60 IRMWLGTFET AEEAARAYDE AACLLHGSNT RTNFITQAPS DSPLAYRIRN LLNSKKGGEQ 120 QHHQSVVASA APSTSATISF SPMPSPSTSS SGCSSNGGLS NGNLSVSGTV QDTQLFDDAY 180 RPDMRSWRRE SGFDTDFTYT TSELGFDRFL YTQETTGLPE ETGSELTEFQ SMKVEGQISA 240 SLHAMNGVEE YMETVHDSSE NLWDLPPLCS LLY

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, root hairs and leaves (PubMed:17827349). Expressed in root epidermis and root hairs (PubMed:23077241). {ECO:0000269\|PubMed:17827349, ECO:0000269\|PubMed:23077241}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in symbiotic nodule signaling in response to rhizobial Nod factors (NFs) (PubMed:17449807, PubMed:17827349). Binds to the GCC-box (NF-responsive box) of ENOD11 promoter. Acts as transcriptional activator of NF-responsive box-containing target gene promoters in root hairs (PubMed:17827349). Functions as a transcriptional regulator required for root infection by symbiotic rhizobia, infection thread (IT) formation and maintenance, and nodule development. Necessary for NF-induced gene expression and spontaneous nodulation activated by CCAMK. Functions downstream of CCAMK to activate nodulation gene expression (PubMed:17449807). Involved in early stages of root nodule development. Functions redundantly with ERN2. Is essential with ERN2 for the initiation of root hair infection, and nodule organogenesis and development. Required for accurate expression of the NF signaling genes ENOD11 and ENOD12 (PubMed:23077241, PubMed:27208242). {ECO:0000269\|PubMed:17449807, ECO:0000269\|PubMed:17827349, ECO:0000269\|PubMed:23077241, ECO:0000269\|PubMed:27208242}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in roots from 1 to 21 day after inoculation with Sinorhizobium meliloti (PubMed:17449807). Induced by Nod factors in root hairs (PubMed:17827349). {ECO:0000269\|PubMed:17449807, ECO:0000269\|PubMed:17827349}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016705337.1	0.0	PREDICTED: ethylene-responsive transcription factor RAP2-11-like
Swissprot	A2Q5W1	1e-86	ERN1_MEDTR; Ethylene-responsive transcription factor ERN1
TrEMBL	A0A1U8KS90	0.0	A0A1U8KS90_GOSHI; ethylene-responsive transcription factor RAP2-11-like
STRING	Gorai.013G115000.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM16007	7	12

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G19790.1	9e-27	related to AP2 11

Publications ? help Back to Top
Cerri MR, et al. Medicago truncatula ERN transcription factors: regulatory interplay with NSP1/NSP2 GRAS factors and expression dynamics throughout rhizobial infection. Plant Physiol., 2012. 160(4): p. 2155-72 [PMID:23077241] Tang H, et al. An improved genome release (version Mt4.0) for the model legume Medicago truncatula. BMC Genomics, 2014. 15: p. 312 [PMID:24767513] Cerri MR, et al. The Symbiosis-Related ERN Transcription Factors Act in Concert to Coordinate Rhizobial Host Root Infection. Plant Physiol., 2016. 171(2): p. 1037-54 [PMID:27208242]