PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_D12G1644
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family TCP
Protein Properties Length: 344aa    MW: 37567.6 Da    PI: 9.1122
Description TCP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_D12G1644genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1TCP130.12.1e-4043159289
          TCP   2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgtssssasec.eaesssssasnsssg.......... 88 
                  ++k+++++++hTkv+gR+RR+R++a+caar+F+L++eLG+++d++tieWLlqqa+pa++++tgt++++a+++  + s +ss+s+ s++          
  Gh_D12G1644  43 PPKRTSTKDRHTKVEGRGRRIRMPATCAARVFQLTRELGHKSDGETIEWLLQQAEPAVIAATGTGTIPANFTsLNISLRSSGSTLSAShlrntyfnpn 140
                  689******************************************************************99987777777777655553433344333 PP

          TCP  89 ..................k 89 
                                    +
  Gh_D12G1644 141 ftsqqlrnmaddssshqqR 159
                  3333333333222222220 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF036342.4E-4147212IPR005333Transcription factor, TCP
PROSITE profilePS5136927.58249103IPR017887Transcription factor TCP subgroup
Sequence ? help Back to Top
Protein Sequence    Length: 344 aa     Download sequence    Send to blast
MIMDGENGIS TSKFPLQLLE KKQPPCPNKG NSETSSEPPK KTPPKRTSTK DRHTKVEGRG  60
RRIRMPATCA ARVFQLTREL GHKSDGETIE WLLQQAEPAV IAATGTGTIP ANFTSLNISL  120
RSSGSTLSAS HLRNTYFNPN FTSQQLRNMA DDSSSHQQRR ILFPEDSLNF PNVNTFLQTK  180
QEMRDSTSVD VSAAEDTNKG KKRRPEHHEL SQNQVGNYLI QSTMGSVPAT FWTITNPSNQ  240
GISGSGAADP MWTFPSANNT NMYTSTTSSG VHFMNFASPM SLLPGQQWGT GIGAGGSFSD  300
SHLGMLQALN AYRPTHSTNV SESPATGSHQ VLHHGEEHRH DSSS
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ghi.139990.0boll| stem
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed in archespores, pollen mother cell, ovule primordia and megaspore mother cells (PubMed:25527103). Expressed in young proliferating tissues (PubMed:21668538). Expressed in developing embryos, and seeds during germination (PubMed:25655823). {ECO:0000269|PubMed:21668538, ECO:0000269|PubMed:25527103, ECO:0000269|PubMed:25655823}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved the regulation of plant development. Together with TCP14, modulates plant stature by promoting cell division in young internodes. Represses cell proliferation in developing leaf blade and specific floral tissues (PubMed:21668538). Together with TCP15, acts downstream of gibberellin (GA), and the stratification pathways that promote seed germination. Involved in the control of cell proliferation at the root apical meristem (RAM) by regulating the activity of CYCB1-1 (PubMed:25655823). Acts together with SPY to promote cytokinin responses that affect leaf shape and trichome development in flowers (PubMed:22267487). Involved in gynoecium and silique development. Modulates the development of the different tissues of the gynoecium through its participation in auxin and cytokinin responses. Modulates the expression of the cytokinin-responsive genes ARR7 and ARR15. May repress the expression of the auxin biosynthetic genes YUC1 and YUC4 (PubMed:26303297). Acts as negative regulator of anthocyanin accumulation under high light conditions. Modulates the expression of transcription factors involved in the induction of anthocyanin biosynthesis genes (PubMed:26574599). Transcription factor involved in the regulation of endoreduplication. Represses endoreduplication by activating the gene expression of the key cell-cycle regulators RBR1 and CYCA2-3 (PubMed:25757472). Regulates the expression of the defense gene pathogenesis-related protein 2 (PR2) in antagonism to SRFR1, a negative regulator of effector-triggered immunity (PubMed:24689742). {ECO:0000269|PubMed:21668538, ECO:0000269|PubMed:22267487, ECO:0000269|PubMed:24689742, ECO:0000269|PubMed:25655823, ECO:0000269|PubMed:25757472, ECO:0000269|PubMed:26303297, ECO:0000269|PubMed:26574599}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Circadian-regulation with the lowest expression in the middle of the dark period (PubMed:21183706). Induced during seed imbibition (PubMed:25655823). Induced by cytokinin (PubMed:26303297). {ECO:0000269|PubMed:21183706, ECO:0000269|PubMed:25655823, ECO:0000269|PubMed:26303297}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankDQ9129410.0DQ912941.1 Gossypium barbadense BHLH mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012438576.10.0PREDICTED: transcription factor TCP15-like
SwissprotQ9C9L27e-61TCP15_ARATH; Transcription factor TCP15
TrEMBLA0A0D2RHE20.0A0A0D2RHE2_GOSRA; Uncharacterized protein
STRINGGorai.008G181600.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM39152757
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G69690.11e-46TCP family protein
Publications ? help Back to Top
  1. Steiner E, et al.
    The Putative O-Linked N-Acetylglucosamine Transferase SPINDLY Inhibits Class I TCP Proteolysis to Promote Sensitivity to Cytokinin.
    Plant Physiol., 2016. 171(2): p. 1485-94
    [PMID:27208284]
  2. Dong H, et al.
    Ubiquitylation activates a peptidase that promotes cleavage and destabilization of its activating E3 ligases and diverse growth regulatory proteins to limit cell proliferation in Arabidopsis.
    Genes Dev., 2017. 31(2): p. 197-208
    [PMID:28167503]
  3. Zhang N, et al.
    MOS1 functions closely with TCP transcription factors to modulate immunity and cell cycle in Arabidopsis.
    Plant J., 2018. 93(1): p. 66-78
    [PMID:29086441]
  4. Mazur MJ, et al.
    Arabidopsis TCP Transcription Factors Interact with the SUMO Conjugating Machinery in Nuclear Foci.
    Front Plant Sci, 2017. 8: p. 2043
    [PMID:29250092]