PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_D11G1176
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family ARR-B
Protein Properties Length: 432aa    MW: 48139.7 Da    PI: 5.0051
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_D11G1176genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like75.28.8e-24180237156
      G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPkti...lelmkvkgLtlehvkSHLQkYRla 56 
                  kpr++Wt+eLH+ Fv av++L G  +A+Pk+i   +++m+v  Lt+++++SHLQkYR++
  Gh_D11G1176 180 KPRMVWTQELHDLFVAAVNEL-GRGNAVPKKIlerMQAMNVTFLTRANIASHLQKYRMH 237
                  79*******************.9*********3333578999***************96 PP

2Response_reg761.4e-25111171107
                   EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTTTHHHHHHHHHTTES CS
  Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahgeeedalealkaGak 95 
                   +livdD+++ + +l+++l+k  y +v+ +++++eal+ll++ +  +D++l+D+ mp+++G+ell+ i+ e  +lp++++++ + +  + + +  Ga 
   Gh_D11G1176  11 ILIVDDDRTCLLVLERMLRKFSY-QVTKCQQAREALALLRQDKnrFDIVLCDLHMPDINGFELLQIIEVEM-DLPVVMMSSDDGKGVVMKGIVHGAC 105
                   8**********************.***************777778**********************8755.9************************ PP

                   EEEESS--HHHH CS
  Response_reg  96 dflsKpfdpeel 107
                   d+l+Kp+ +e++
   Gh_D11G1176 106 DYLVKPVRMEAI 117
                   ******998876 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.40.50.23003.3E-388148No hitNo description
SuperFamilySSF521725.69E-348131IPR011006CheY-like superfamily
SMARTSM004481.7E-289121IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011041.14910125IPR001789Signal transduction response regulator, receiver domain
PfamPF000721.0E-2211117IPR001789Signal transduction response regulator, receiver domain
CDDcd001566.54E-2612117No hitNo description
PROSITE profilePS5129410.376177239IPR017930Myb domain
SuperFamilySSF466893.05E-17179240IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.602.6E-24179240IPR009057Homeodomain-like
TIGRFAMsTIGR015572.8E-21180237IPR006447Myb domain, plants
PfamPF002492.5E-8182235IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 432 aa     Download sequence    Send to blast
MAGEFPAGLK ILIVDDDRTC LLVLERMLRK FSYQVTKCQQ AREALALLRQ DKNRFDIVLC  60
DLHMPDINGF ELLQIIEVEM DLPVVMMSSD DGKGVVMKGI VHGACDYLVK PVRMEAIGLI  120
WQHVVRKKKK RFSGEITRSL PLQRADNAVP AMDKRSLKYR KRTSEDEDVA EDGESSEGKK  180
PRMVWTQELH DLFVAAVNEL GRGNAVPKKI LERMQAMNVT FLTRANIASH LQKYRMHLQK  240
EGAVPSSDSR DVNAYIDHRN LQFQPSPTTP YQLPMQNLIT ERANENVLSI APSHVDGGSN  300
IFNSNIASES SCSLPTQVTL YDLYRANLLY QNDFPPISNG VAISNDNEFP PNDGVANSND  360
ESLYCNVVDG TELSNPFSAV AVDGTELSNP LSAVAVDGTE LSNPLSAVED LIHEPSFLVG  420
QYDQQAFFRG PI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A2e-16179240462ARR10-B
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1125130RKKKKR
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed only from 5 days post germination onward, when the fixed meristem cell number is established. {ECO:0000269|PubMed:17363254}.
UniprotTISSUE SPECIFICITY: Detected in the whole plant. Expressed at the root transition zone (PubMed:17363254). {ECO:0000269|PubMed:15173562, ECO:0000269|PubMed:17363254, ECO:0000269|PubMed:9891419}.
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Regulates SHY2 by binding to its promoter (PubMed:19039136). Involved in the root-meristem size determination through the regulation of cell differentiation (PubMed:17363254). {ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:11691951, ECO:0000269|PubMed:17363254, ECO:0000269|PubMed:19039136}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by gibberellin. {ECO:0000269|PubMed:20605455}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016695969.10.0PREDICTED: two-component response regulator ARR1-like isoform X1
SwissprotQ940D02e-81ARR1_ARATH; Two-component response regulator ARR1
TrEMBLA0A1U8K5R00.0A0A1U8K5R0_GOSHI; two-component response regulator ARR1-like isoform X1
TrEMBLA0A2P5RNR60.0A0A2P5RNR6_GOSBA; Uncharacterized protein
STRINGGorai.007G125800.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM2484834
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G16857.14e-84response regulator 1
Publications ? help Back to Top
  1. Bürkle L,Meyer S,Dortay H,Lehrach H,Heyl A
    In vitro recombination cloning of entire cDNA libraries in Arabidopsis thaliana and its application to the yeast two-hybrid system.
    Funct. Integr. Genomics, 2005. 5(3): p. 175-83
    [PMID:15714319]
  2. Moubayidin L, et al.
    Spatial coordination between stem cell activity and cell differentiation in the root meristem.
    Dev. Cell, 2013. 26(4): p. 405-15
    [PMID:23987513]
  3. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  4. Kurepa J,Li Y,Perry SE,Smalle JA
    Ectopic expression of the phosphomimic mutant version of Arabidopsis response regulator 1 promotes a constitutive cytokinin response phenotype.
    BMC Plant Biol., 2014. 14: p. 28
    [PMID:24423196]
  5. Cortleven A, et al.
    A novel protective function for cytokinin in the light stress response is mediated by the Arabidopsis histidine kinase2 and Arabidopsis histidine kinase3 receptors.
    Plant Physiol., 2014. 164(3): p. 1470-83
    [PMID:24424319]
  6. Marín-de la Rosa N, et al.
    Genome Wide Binding Site Analysis Reveals Transcriptional Coactivation of Cytokinin-Responsive Genes by DELLA Proteins.
    PLoS Genet., 2015. 11(7): p. e1005337
    [PMID:26134422]
  7. D'Alessandro S,Golin S,Hardtke CS,Lo Schiavo F,Zottini M
    The co-chaperone p23 controls root development through the modulation of auxin distribution in the Arabidopsis root meristem.
    J. Exp. Bot., 2015. 66(16): p. 5113-22
    [PMID:26163704]
  8. Jiang L, et al.
    Strigolactones spatially influence lateral root development through the cytokinin signaling network.
    J. Exp. Bot., 2016. 67(1): p. 379-89
    [PMID:26519957]
  9. Moubayidin L, et al.
    A SCARECROW-based regulatory circuit controls Arabidopsis thaliana meristem size from the root endodermis.
    Planta, 2016. 243(5): p. 1159-68
    [PMID:26848984]
  10. Muraro D, et al.
    A multi-scale model of the interplay between cell signalling and hormone transport in specifying the root meristem of Arabidopsis thaliana.
    J. Theor. Biol., 2016. 404: p. 182-205
    [PMID:27157127]
  11. Cortleven A, et al.
    Cytokinin Regulates the Etioplast-Chloroplast Transition through the Two-Component Signaling System and Activation of Chloroplast-Related Genes.
    Plant Physiol., 2016. 172(1): p. 464-78
    [PMID:27388681]
  12. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  13. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  14. Kushwah S,Laxmi A
    The interaction between glucose and cytokinin signaling in controlling Arabidopsis thaliana seedling root growth and development.
    Plant Signal Behav, 2017. 12(5): p. e1312241
    [PMID:28467152]
  15. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  16. Kobayashi K,Iwase A
    Simultaneous but spatially different regulation of non-photosynthetic callus formation and photosynthetic root development after shoot removal.
    Plant Signal Behav, 2017. 12(6): p. e1338999
    [PMID:28594268]
  17. Liu B,De Storme N,Geelen D
    Cold interferes with male meiotic cytokinesis in Arabidopsis thaliana independently of the AHK2/3-AHP2/3/5 cytokinin signaling module.
    Cell Biol. Int., 2017. 41(8): p. 879-889
    [PMID:28618065]
  18. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  19. Yan Z, et al.
    Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1.
    Plant Physiol., 2017. 175(3): p. 1438-1454
    [PMID:28931628]
  20. Rong XF, et al.
    Type-B ARRs Control Carpel Regeneration Through Mediating AGAMOUS Expression in Arabidopsis.
    Plant Cell Physiol., 2018. 59(4): p. 756-764
    [PMID:29186581]
  21. Bustillo-Avendaño E, et al.
    Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis.
    Plant Physiol., 2018. 176(2): p. 1709-1727
    [PMID:29233938]
  22. Waldie T,Leyser O
    Cytokinin Targets Auxin Transport to Promote Shoot Branching.
    Plant Physiol., 2018. 177(2): p. 803-818
    [PMID:29717021]