PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_D08G0786

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

C2H2

Protein Properties

Length: 563aa MW: 61367 Da PI: 8.7327

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_D08G0786	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	17	1.6e-05	100	122	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H Gh_D08G0786 100 FVCEICNKGFQRDQNLQLHRRGH 122 89*******************88 PP
2	zf-C2H2	15.4	5.2e-05	176	198	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC +C+k + +s+ k H++t+ Gh_D08G0786 176 WKCDKCSKKYAVQSDWKAHQKTC 198 58*******************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	1.9E-5	99	122	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	6.31E-8	99	122	No hit	No description
SMART	SM00355	0.017	100	122	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.949	100	122	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	102	122	IPR007087	Zinc finger, C2H2
SMART	SM00355	98	141	171	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	6.6E-5	164	197	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	6.31E-8	171	197	No hit	No description
SMART	SM00355	94	176	196	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 563 aa Download sequence Send to blast
MSNMSGDDDG SFSSGEEVQQ QKQMLQNNFA ASGSGPSAAS NSNNGSQQAV KKKRNLPGTP 60 GNYIYNSFPK SILIMLSSII NPNAEVIALS PTTLMATNRF VCEICNKGFQ RDQNLQLHRR 120 GHNLPWKLKQ RTTTEVKKRV YICPEPTCVH HNPARALGDL TGIKKHFSRK HGEKKWKCDK 180 CSKKYAVQSD WKAHQKTCGT REYKCDCGTI FSRRDSFITH RAFCDALAEE NNKVNQGIMN 240 NMGSNMQNQI PELISSMQTS NGISDLGNFD PKSPLKSHPQ ELVPMPFMSM NMGGGMFSSS 300 SSSLFGGPRS VSSASSSLQL SSNSSSGLNY LQDSKNGCPI MSATALLQKA AQMGATASNS 360 INSPMMQKSF ASSMAGPEQT IRPPSFGGIE QQNTSYDQFP SQTDQTSMVG ISEAGGFSNP 420 FMQKSPSEMA QLFTAATGSS AMNEMGMFTN MFINGADRNQ VGLMKSMEQE DSGSSSLLQG 480 RTQLPAAMFG TSSGNGGSNM TTLDFMGIGG SRPNSLHEQQ QQQQQRMELE AISQQRLPMI 540 NPFHLQQQLS HGDSAIEKPI WEV

Sequence ? help Back to Top

Protein Sequence Length: 563 aa Download sequence Send to blast

MSNMSGDDDG SFSSGEEVQQ QKQMLQNNFA ASGSGPSAAS NSNNGSQQAV KKKRNLPGTP  60
GNYIYNSFPK SILIMLSSII NPNAEVIALS PTTLMATNRF VCEICNKGFQ RDQNLQLHRR  120
GHNLPWKLKQ RTTTEVKKRV YICPEPTCVH HNPARALGDL TGIKKHFSRK HGEKKWKCDK  180
CSKKYAVQSD WKAHQKTCGT REYKCDCGTI FSRRDSFITH RAFCDALAEE NNKVNQGIMN  240
NMGSNMQNQI PELISSMQTS NGISDLGNFD PKSPLKSHPQ ELVPMPFMSM NMGGGMFSSS  300
SSSLFGGPRS VSSASSSLQL SSNSSSGLNY LQDSKNGCPI MSATALLQKA AQMGATASNS  360
INSPMMQKSF ASSMAGPEQT IRPPSFGGIE QQNTSYDQFP SQTDQTSMVG ISEAGGFSNP  420
FMQKSPSEMA QLFTAATGSS AMNEMGMFTN MFINGADRNQ VGLMKSMEQE DSGSSSLLQG  480
RTQLPAAMFG TSSGNGGSNM TTLDFMGIGG SRPNSLHEQQ QQQQQRMELE AISQQRLPMI  540
NPFHLQQQLS HGDSAIEKPI WEV

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	2e-34	172	241	3	72	Zinc finger protein JACKDAW
5b3h_F	2e-34	172	241	3	72	Zinc finger protein JACKDAW
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Observed in vegetative tissues. Mainly expressed in hypocotyls, petioles, shoot apices, root tips, and trichomes, and, at low levels, in leaves, stems and flowers. {ECO:0000269\|PubMed:25035403}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269\|PubMed:25035403}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JX578100	1e-129	JX578100.1 Gossypium hirsutum clone NBRI_GE10050 microsatellite sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016739476.1	0.0	PREDICTED: protein indeterminate-domain 2-like
Swissprot	Q9SCQ6	1e-110	IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBL	A0A2P5YNG6	0.0	A0A2P5YNG6_GOSBA; Uncharacterized protein
STRING	Gorai.004G088400.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM15443	8	18

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G44160.1	9e-95	C2H2-like zinc finger protein

Publications ? help Back to Top
Fukazawa J, et al. DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis. Plant Cell, 2014. 26(7): p. 2920-38 [PMID:25035403] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755] Khare D, et al. Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana. New Phytol., 2017. 213(3): p. 1257-1273 [PMID:27768815]