PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_D06G2091
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family ERF
Protein Properties Length: 396aa    MW: 44013.5 Da    PI: 4.6558
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_D06G2091genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP262.11.3e-19123172255
          AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                  +y+G+r+++ +g+W+AeIrdp++     r++lg+f taeeAa+a++a +++++g
  Gh_D06G2091 123 QYRGIRQRP-WGKWAAEIRDPRK---GVRVWLGTFNTAEEAARAYDAEALRIRG 172
                  69*******.**********954...4*************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5103224.553123180IPR001471AP2/ERF domain
CDDcd000181.93E-33123181No hitNo description
SuperFamilySSF541711.63E-22123182IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.101.2E-32123182IPR001471AP2/ERF domain
SMARTSM003801.9E-37123186IPR001471AP2/ERF domain
PRINTSPR003671.2E-11124135IPR001471AP2/ERF domain
PfamPF008472.2E-12124172IPR001471AP2/ERF domain
PRINTSPR003671.2E-11146162IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 396 aa     Download sequence    Send to blast
MCGGAIISDF IPPARSRLVT ANYLWPDLKK SCSKKWSGRK HSKKPAVGFE DDFEADFQVF  60
KDEDSDVDDF DDDVDDVLAD VKSFAFSATK KPSPAVSHGS NSIKSVEFNG QAEKSAKRKR  120
KNQYRGIRQR PWGKWAAEIR DPRKGVRVWL GTFNTAEEAA RAYDAEALRI RGKKAKVNFP  180
DETPRTSPKN AAKMNSQKPL SGSNLSSVQS SLNPDFSYSN KHEQGYYDTM GFIEEKSLMD  240
QFAYADPVRA AVDDGLKPFA EPENTALYFN SDQGSNNFDS SDLVWGEQGA KTPEISSSLE  300
PTLEVNEFLD NANPTKKLKP SSNNVMPTGG DNSVKSLSDE LLAMDNHVNY FQTPFIDENW  360
NVSIDDFLNG DATQDGGNEM GFWSFDDFPS IDGGVF
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A8e-22123180260ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
5wx9_A5e-211221821374Ethylene-responsive transcription factor ERF096
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ghi.164710.0boll| ovule
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO604592520.0
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Highly expressed in seedlings, leaves, flowers, siliques and germinating seeds. {ECO:0000269|PubMed:22020282}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the activation of hypoxic gene expression and in ethylene response. Partially redundant with RAP2-2. Acts as a downstream regulator in the ethylene signaling pathway. {ECO:0000269|PubMed:22020282, ECO:0000269|PubMed:22530619}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by hypoxia but not by ethylene. {ECO:0000269|PubMed:22020282}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY8171340.0AY817134.1 Gossypium hirsutum putative ethylene responsive element binding protein mRNA, complete cds.
GenBankKP7802010.0KP780201.1 Gossypium hirsutum C-repeat binding factor 18 (CBF18) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016752083.10.0PREDICTED: ethylene-responsive transcription factor RAP2-12-like
SwissprotQ9SSA83e-80RA212_ARATH; Ethylene-responsive transcription factor RAP2-12
TrEMBLA0A1U8PP150.0A0A1U8PP15_GOSHI; ethylene-responsive transcription factor RAP2-12-like
STRINGGorai.010G236100.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM10281650
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G53910.36e-78related to AP2 12
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Kosmacz M, et al.
    The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration.
    Plant Cell Environ., 2015. 38(6): p. 1094-103
    [PMID:25438831]
  3. Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F
    Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana.
    Plant Sci., 2015. 236: p. 37-43
    [PMID:26025519]
  4. Gasch P, et al.
    Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis.
    Plant Cell, 2016. 28(1): p. 160-80
    [PMID:26668304]
  5. Gonzali S, et al.
    Universal stress protein HRU1 mediates ROS homeostasis under anoxia.
    Nat Plants, 2015. 1: p. 15151
    [PMID:27251529]
  6. Paul MV, et al.
    Oxygen Sensing via the Ethylene Response Transcription Factor RAP2.12 Affects Plant Metabolism and Performance under Both Normoxia and Hypoxia.
    Plant Physiol., 2016. 172(1): p. 141-53
    [PMID:27372243]
  7. Shahzad Z, et al.
    A Potassium-Dependent Oxygen Sensing Pathway Regulates Plant Root Hydraulics.
    Cell, 2016. 167(1): p. 87-98.e14
    [PMID:27641502]
  8. Yao Y, et al.
    ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis.
    New Phytol., 2017. 213(4): p. 1667-1681
    [PMID:28164334]
  9. Giuntoli B,Licausi F,van Veen H,Perata P
    Functional Balancing of the Hypoxia Regulators RAP2.12 and HRA1 Takes Place in vivo in Arabidopsis thaliana Plants.
    Front Plant Sci, 2017. 8: p. 591
    [PMID:28487707]
  10. Yao Y,Chen X,Wu AM
    ERF-VII members exhibit synergistic and separate roles in Arabidopsis.
    Plant Signal Behav, 2017. 12(6): p. e1329073
    [PMID:28537474]
  11. Eysholdt-Derzsó E,Sauter M
    Root Bending Is Antagonistically Affected by Hypoxia and ERF-Mediated Transcription via Auxin Signaling.
    Plant Physiol., 2017. 175(1): p. 412-423
    [PMID:28698356]
  12. Giuntoli B, et al.
    Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana.
    Plant Cell Environ., 2017. 40(10): p. 2333-2346
    [PMID:28741696]