PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_D04G1896
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family WRKY
Protein Properties Length: 485aa    MW: 52998.5 Da    PI: 8.7313
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_D04G1896genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY108.92.4e-34205261259
                  --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
         WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                  +DgynWrKYGqK+vkgsefprsYY+Ct++gCpvkkkvers  d++v+ei+Y+g+Hnh+
  Gh_D04G1896 205 SDGYNWRKYGQKQVKGSEFPRSYYKCTHPGCPVKKKVERSL-DGQVTEIIYKGQHNHQ 261
                  7****************************************.***************8 PP
2WRKY107.66.2e-34370428159
                  ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
         WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                  ldDgy+WrKYGqK+vkg+++prsYY+Ct++gC+v+k+ver+++dpk+v++tYeg+Hnh+
  Gh_D04G1896 370 LDDGYRWRKYGQKVVKGNPYPRSYYKCTTPGCNVRKHVERASTDPKAVITTYEGKHNHD 428
                  59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5081124.604199263IPR003657WRKY domain
Gene3DG3DSA:2.20.25.802.0E-29200263IPR003657WRKY domain
SuperFamilySSF1182903.4E-26203263IPR003657WRKY domain
SMARTSM007742.7E-38204262IPR003657WRKY domain
PfamPF031062.3E-26206261IPR003657WRKY domain
Gene3DG3DSA:2.20.25.801.8E-37355430IPR003657WRKY domain
SuperFamilySSF1182908.37E-30362430IPR003657WRKY domain
PROSITE profilePS5081138.836365430IPR003657WRKY domain
SMARTSM007741.3E-39370429IPR003657WRKY domain
PfamPF031063.1E-26371428IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 485 aa     Download sequence    Send to blast
MADEMQEQKP PSKTVASSKR PMITPPPRPF SEALFNGGAG LMGFSPGPMT LVSNFFSDTT  60
DDSKSFSQLL AGAMASPAAQ KLTEEQAEGG GVNTGLRFKQ NKPAGLAITQ QPSSFVMPQG  120
LLSPASLLES PGFSVFSPGP QGPFGMTHQQ AVAQVTAQVA QANSHTQIHA DTATSLQDSS  180
VMIKQPSDVS QSDQRSQPAS DKHASDGYNW RKYGQKQVKG SEFPRSYYKC THPGCPVKKK  240
VERSLDGQVT EIIYKGQHNH QPPQQNKRAK GNGTSNNRGN SESTSQLHST NLNIIKEGTC  300
SSMSKKDQES SQATTDLLSG TSDSDDEKDE DEPDTKRRSM EIRVSEPCSS HRTVTEPRII  360
VQTTSEVDLL DDGYRWRKYG QKVVKGNPYP RSYYKCTTPG CNVRKHVERA STDPKAVITT  420
YEGKHNHDVP AARTSSHNTA SSNATQVRTQ NIVTDNNHGV NNSVDSTNDR QRPVARLRLK  480
EEQET
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A2e-44206431878Probable WRKY transcription factor 4
2lex_A2e-44206431878Probable WRKY transcription factor 4
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: In young, mature and senescent leaves. {ECO:0000269|PubMed:11722756}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Has a positive role in resistance to necrotrophic pathogens (e.g. Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e.g. Pseudomonas syringae). {ECO:0000269|PubMed:18570649, ECO:0000269|PubMed:22219184}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By biotic and abiotic stresses such as pathogen infection (e.g. Botrytis cinerea and Pseudomonas syringae), salicylic acid (SA), jasmonic acid (JA), ethylene (ACC), liquid infiltration or spraying, and strongly during leaf senescence. {ECO:0000269|PubMed:11449049, ECO:0000269|PubMed:11722756, ECO:0000269|PubMed:18570649}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankKF6697670.0KF669767.1 Gossypium hirsutum WRKY transcription factor 40 (WRKY40) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_012460621.10.0PREDICTED: probable WRKY transcription factor 4 isoform X1
SwissprotQ9XI901e-171WRKY4_ARATH; Probable WRKY transcription factor 4
TrEMBLA0A1U8INN50.0A0A1U8INN5_GOSHI; probable WRKY transcription factor 4
STRINGGorai.012G186000.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM15342792
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G13960.11e-142WRKY DNA-binding protein 4
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Aamir M, et al.
    Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach.
    Front Plant Sci, 2017. 8: p. 819
    [PMID:28611792]