PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_D04G1000

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

GRF

Protein Properties

Length: 363aa MW: 39963.1 Da PI: 9.1009

Description

GRF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_D04G1000	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRC	79.1	4.2e-25	146	189	1	44
WRC 1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkske 44 d+epgrCrRtDGKkWRCsr+v++g+k+CErH+hrgr+rsrk++e Gh_D04G1000 146 DPEPGRCRRTDGKKWRCSRDVVAGQKYCERHVHRGRNRSRKPVE 189 79***************************************987 PP
2	QLQ	48	3.7e-17	73	108	1	36
QLQ 1 saFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiq 36 s F+ +Q+q+L+ Q+l+++y++a++ vPp+Llq i Gh_D04G1000 73 SFFSLSQWQELELQALIFRYMLAGAAVPPQLLQSIE 108 67*******************************996 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00951	7.9E-10	73	109	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51666	18.81	74	109	IPR014978	Glutamine-Leucine-Glutamine, QLQ
Pfam	PF08880	5.4E-12	75	107	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51667	24.987	146	190	IPR014977	WRC domain
Pfam	PF08879	6.4E-22	147	189	IPR014977	WRC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005524	Molecular Function	ATP binding

Sequence ? help Back to Top
Protein Sequence Length: 363 aa Download sequence Send to blast
MDLHLKQCRN LHESDHQQPP PSANIPKLHF HHHHHQHPSP LPLLVPHHHC KSSSNNLPPL 60 PHSSSTFPSR MGSFFSLSQW QELELQALIF RYMLAGAAVP PQLLQSIENS TILHSPSYFL 120 HHPIRHVSHY QPPLLQSGYW GRAAMDPEPG RCRRTDGKKW RCSRDVVAGQ KYCERHVHRG 180 RNRSRKPVEM LKSSGACTTI INNSTLVGAA DGVVDVGCGG LKPTSLIPNS PLELAGDRAN 240 SLLLSGHSPP VDLLRLNYSS SDSKNVHKGL FEAQNYGQML RQFFDDRPRS LQQPDNPAES 300 PMSSATCLSI SMPGNSSSDV SLKLSTGKGD QLNWAAGWAS NQVASMGGPL AEALRSSMSN 360 SQP

Sequence ? help Back to Top

Protein Sequence Length: 363 aa Download sequence Send to blast

MDLHLKQCRN LHESDHQQPP PSANIPKLHF HHHHHQHPSP LPLLVPHHHC KSSSNNLPPL  60
PHSSSTFPSR MGSFFSLSQW QELELQALIF RYMLAGAAVP PQLLQSIENS TILHSPSYFL  120
HHPIRHVSHY QPPLLQSGYW GRAAMDPEPG RCRRTDGKKW RCSRDVVAGQ KYCERHVHRG  180
RNRSRKPVEM LKSSGACTTI INNSTLVGAA DGVVDVGCGG LKPTSLIPNS PLELAGDRAN  240
SLLLSGHSPP VDLLRLNYSS SDSKNVHKGL FEAQNYGQML RQFFDDRPRS LQQPDNPAES  300
PMSSATCLSI SMPGNSSSDV SLKLSTGKGD QLNWAAGWAS NQVASMGGPL AEALRSSMSN  360
SQP

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed during the early stages of leaf development and expression decreases with the maturation of the leaf. {ECO:0000269\|PubMed:20023165}.
Uniprot	TISSUE SPECIFICITY: Strongly expressed in actively growing and developing tissues, such as roots, upper stems, and shoot tips containing the shoot apical meristem (SAM) and flower buds. Also expressed in mature flowers, but weakly expressed in mature stems and leaves. {ECO:0000269\|PubMed:12974814}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. {ECO:0000250}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). {ECO:0000269\|PubMed:15200956, ECO:0000269\|PubMed:19453503, ECO:0000269\|PubMed:20023165}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	JX582593	2e-60	JX582593.1 Gossypium hirsutum clone NBRI_GE15450 microsatellite sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012441744.1	0.0	PREDICTED: growth-regulating factor 3-like isoform X1
Swissprot	Q8L8A7	9e-75	GRF4_ARATH; Growth-regulating factor 4
TrEMBL	A0A0D2QW66	0.0	A0A0D2QW66_GOSRA; Uncharacterized protein
STRING	Gorai.009G406500.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1926	26	67

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G52910.1	7e-76	growth-regulating factor 4

Publications ? help Back to Top
Kuijt SJ, et al. Interaction between the GROWTH-REGULATING FACTOR and KNOTTED1-LIKE HOMEOBOX families of transcription factors. Plant Physiol., 2014. 164(4): p. 1952-66 [PMID:24532604] Cao Y,Han Y,Jin Q,Lin Y,Cai Y Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa). Front Plant Sci, 2016. 7: p. 1750 [PMID:27933074]