PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_D03G0282

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

GRF

Protein Properties

Length: 561aa MW: 61241.1 Da PI: 8.2238

Description

GRF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_D03G0282	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRC	76.7	2.3e-24	210	254	1	45
WRC 1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkskee 45 d+epgrCrRtDGKkWRCsr++++++k+CErH++rgr+rsrk++e Gh_D03G0282 210 DPEPGRCRRTDGKKWRCSRDAVADQKYCERHINRGRHRSRKPVEG 254 79****************************************985 PP
2	QLQ	49.4	1.3e-17	142	176	3	37
QLQ 3 FTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 +T++Q+ +L +Q+l+yKy+++n+PvP++Ll +++k Gh_D03G0282 142 LTPSQWIELQHQALIYKYIMSNVPVPSNLLTPLKK 176 8******************************9986 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM00951	7.5E-8	140	176	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51666	19.511	141	176	IPR014978	Glutamine-Leucine-Glutamine, QLQ
Pfam	PF08880	6.2E-12	142	174	IPR014978	Glutamine-Leucine-Glutamine, QLQ
PROSITE profile	PS51667	25.287	210	254	IPR014977	WRC domain
Pfam	PF08879	7.1E-21	211	253	IPR014977	WRC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0005524	Molecular Function	ATP binding

Sequence ? help Back to Top
Protein Sequence Length: 561 aa Download sequence Send to blast
MDFGVLGLDG IVGPNNGAPS PSPSPSPSPS PPVESKPKLF GSGFTKQERS SDSAEEEDHW 60 KSCKVPKTMP LHQGIPLLRS NETPQQQQDH MISFSSLKSA LPFIRKDGNF MEKTTQSNDF 120 SMYTRNAGYG SGNLNATMHG VLTPSQWIEL QHQALIYKYI MSNVPVPSNL LTPLKKSLYP 180 YGFTSSSVGS LPYNSLGWGS FHLRYTGSTD PEPGRCRRTD GKKWRCSRDA VADQKYCERH 240 INRGRHRSRK PVEGQTGHTA TNSKVESMSS SMLASAKTSG GAANSLAIAL QHRSGAADPS 300 SDTLVNRIQD QRGFSVLSST TNLKSDDSTT FTITKQGVPF VESSLSDFGH VASDSLVNPS 360 HKSYYMNSKE YGHGLFLDFT GQETQDQTPP HQFIDNWPKD QSSRSIVTWP NELKPDWTQL 420 SMSIPMVTSE FSSTLSSPVK EKLDLSSLRL VQEFDQIQMG LGVNNDITEQ TKRQPNWIPI 480 SWGGSMGGPL GEILNNTTNN AGSCQNSSTL TFLSEGLDGN RIQLQNTPFS SLSNSSSGSS 540 PIAENNKKLL GAASVPSIIR S

Sequence ? help Back to Top

Protein Sequence Length: 561 aa Download sequence Send to blast

MDFGVLGLDG IVGPNNGAPS PSPSPSPSPS PPVESKPKLF GSGFTKQERS SDSAEEEDHW  60
KSCKVPKTMP LHQGIPLLRS NETPQQQQDH MISFSSLKSA LPFIRKDGNF MEKTTQSNDF  120
SMYTRNAGYG SGNLNATMHG VLTPSQWIEL QHQALIYKYI MSNVPVPSNL LTPLKKSLYP  180
YGFTSSSVGS LPYNSLGWGS FHLRYTGSTD PEPGRCRRTD GKKWRCSRDA VADQKYCERH  240
INRGRHRSRK PVEGQTGHTA TNSKVESMSS SMLASAKTSG GAANSLAIAL QHRSGAADPS  300
SDTLVNRIQD QRGFSVLSST TNLKSDDSTT FTITKQGVPF VESSLSDFGH VASDSLVNPS  360
HKSYYMNSKE YGHGLFLDFT GQETQDQTPP HQFIDNWPKD QSSRSIVTWP NELKPDWTQL  420
SMSIPMVTSE FSSTLSSPVK EKLDLSSLRL VQEFDQIQMG LGVNNDITEQ TKRQPNWIPI  480
SWGGSMGGPL GEILNNTTNN AGSCQNSSTL TFLSEGLDGN RIQLQNTPFS SLSNSSSGSS  540
PIAENNKKLL GAASVPSIIR S

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Ghi.2980	0.0	ovule\| root

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed during the early stages of leaf development and expression decreases with the maturation of the leaf. {ECO:0000269\|PubMed:20023165}.
Uniprot	TISSUE SPECIFICITY: Strongly expressed in actively growing and developing tissues, such as roots, upper stems, and shoot tips containing the shoot apical meristem (SAM) and flower buds. Also expressed in mature flowers, but weakly expressed in mature stems and leaves. {ECO:0000269\|PubMed:12974814}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. microRNA396-GRF1/GRF3 regulatory module acts as a developmental regulator in the reprogramming of root cells during cyst nematode infection, leading to the formation of the syncytium. {ECO:0000269\|PubMed:12974814, ECO:0000269\|PubMed:15326298, ECO:0000269\|PubMed:22419826, ECO:0000269\|PubMed:22751317}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). Up-regulated in response to cyst nematode infection. {ECO:0000269\|PubMed:15200956, ECO:0000269\|PubMed:19453503, ECO:0000269\|PubMed:20023165, ECO:0000269\|PubMed:22419826}.

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN681875	3e-41	LN681875.1 Cucumis melo genomic scaffold, anchoredscaffold00007.
GenBank	LN713262	3e-41	LN713262.1 Cucumis melo genomic chromosome, chr_8.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016720148.1	0.0	PREDICTED: growth-regulating factor 1-like
Swissprot	O81001	1e-118	GRF1_ARATH; Growth-regulating factor 1
TrEMBL	A0A1U8M3B8	0.0	A0A1U8M3B8_GOSHI; growth-regulating factor 1-like
STRING	Gorai.003G032300.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1454	28	86

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G22840.1	1e-120	growth-regulating factor 1

Publications ? help Back to Top
Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves. Plant Cell, 2013. 25(9): p. 3570-83 [PMID:24076976] Liu J,Rice JH,Chen N,Baum TJ,Hewezi T Synchronization of developmental processes and defense signaling by growth regulating transcription factors. PLoS ONE, 2014. 9(5): p. e98477 [PMID:24875638] Cao Y,Han Y,Jin Q,Lin Y,Cai Y Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa). Front Plant Sci, 2016. 7: p. 1750 [PMID:27933074]