PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Gh_A10G2018

Organism

Gossypium hirsutum

Taxonomic ID

3635

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

TALE

Protein Properties

Length: 276aa MW: 30954.1 Da PI: 7.276

Description

TALE family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Gh_A10G2018	genome	NAU-NBI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	32.3	1.6e-10	106	143	19	54
HHH..SSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHH CS Homeobox 19 Fek..nrypsaeereeLAkklgLterqVkvWFqNrRak 54 Fe ++yps +e+ LA+++gL+ +qV++WF N R + Gh_A10G2018 106 FEHflHPYPSDTEKLMLAQQTGLSRTQVSNWFINARVR 143 665559******************************98 PP
2	BELL	48.4	2.3e-16	1	42	30	71
BELL 30 lqtvissFeavaglgsakpYtslAlkaiSrhFrcLkdaiaeq 71 +q v+ssF++v glg+a+pY+ +A ka+++hF cLk+ai +q Gh_A10G2018 1 MQSVVSSFKCVSGLGNAAPYVCFAFKAVAKHFSCLKNAILDQ 42 9**************************************988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF07526	1.8E-11	1	39	IPR006563	POX domain
CDD	cd00086	1.47E-13	87	148	No hit	No description
SMART	SM00389	1.3E-11	87	151	IPR001356	Homeobox domain
PROSITE profile	PS50071	12.115	88	147	IPR001356	Homeobox domain
SuperFamily	SSF46689	1.28E-18	90	154	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	2.0E-28	90	151	IPR009057	Homeodomain-like
Pfam	PF05920	9.0E-19	104	143	IPR008422	Homeobox KN domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 276 aa Download sequence Send to blast
MQSVVSSFKC VSGLGNAAPY VCFAFKAVAK HFSCLKNAIL DQTQFAGKTV SIVNNGGVDK 60 VNVPGVWTSD QQGINNQNPI FLHHPLWRSQ RGLPDHAVAV LKTWLFEHFL HPYPSDTEKL 120 MLAQQTGLSR TQVSNWFINA RVRLWKPMVE EIHNLELRQA QIQTQTTNQD PKLPHFITSQ 180 EVQNVQTKRP RNEAVYDEET ELQKSTSPCI DQIPSNQHNN IGVGGTSGFC LALCLNQNNG 240 VELEQQPLLP MNLCHNFRLE SDGELSLKPG FDVGRQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3k2a_A	4e-16	93	151	5	63	Homeobox protein Meis2
3k2a_B	4e-16	93	151	5	63	Homeobox protein Meis2
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	DEVELOPMENTAL STAGE: Expressed during late heart stage embryo in the SAM region between the two developing cotyledons. Expression is initially down-regulated in incipient floral primordia but a strong expression is subsequently detected in the central region of young floral primordia and the inner whorl of developing flowers. In fruit, is expressed in the replum of developing ovaries. {ECO:0000269\|PubMed:12874117}.
Uniprot	TISSUE SPECIFICITY: Predominantly expressed in stems, inflorescences and flowers. {ECO:0000269\|PubMed:12874117, ECO:0000269\|PubMed:12897247, ECO:0000269\|PubMed:13678595, ECO:0000269\|PubMed:15019989}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that is involved in the preservation of the spiral phyllotactic arrangement leading to a regular pattern of organ initiation. Required for maintenance of stem cell fate in the shoot apical meristem, and is essential for specifying floral primordia and establishing early internode patterning events during inflorescence development. Acts as transcription repressor of AG expression in floral and inflorescence meristems. Is also responsive of the nuclear import of SHOOT MERISTEMLESS (STM). In the fruit, plays a central role in patterning by negatively regulating SHP expression in order to prevent replum cells from adopting a valve margin cell fate. {ECO:0000269\|PubMed:12874117, ECO:0000269\|PubMed:12897247, ECO:0000269\|PubMed:13678595, ECO:0000269\|PubMed:15019989, ECO:0000269\|PubMed:15120075, ECO:0000269\|PubMed:15155890, ECO:0000269\|PubMed:16741748}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016724887.1	0.0	PREDICTED: BEL1-like homeodomain protein 9
Swissprot	Q9LZM8	4e-53	BLH9_ARATH; BEL1-like homeodomain protein 9
TrEMBL	A0A1U8MDG9	0.0	A0A1U8MDG9_GOSHI; BEL1-like homeodomain protein 9
STRING	Gorai.011G271200.1	0.0	(Gossypium raimondii)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM17615	7	9

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G02030.1	2e-55	TALE family protein

Publications ? help Back to Top
Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Pabón-Mora N,Wong GK,Ambrose BA Evolution of fruit development genes in flowering plants. Front Plant Sci, 2014. 5: p. 300 [PMID:25018763] Khan M, et al. Repression of Lateral Organ Boundary Genes by PENNYWISE and POUND-FOOLISH Is Essential for Meristem Maintenance and Flowering in Arabidopsis. Plant Physiol., 2015. 169(3): p. 2166-86 [PMID:26417006] Andrés F, et al. Floral Induction in Arabidopsis by FLOWERING LOCUS T Requires Direct Repression of BLADE-ON-PETIOLE Genes by the Homeodomain Protein PENNYWISE. Plant Physiol., 2015. 169(3): p. 2187-99 [PMID:26417007] Bencivenga S,Serrano-Mislata A,Bush M,Fox S,Sablowski R Control of Oriented Tissue Growth through Repression of Organ Boundary Genes Promotes Stem Morphogenesis. Dev. Cell, 2016. 39(2): p. 198-208 [PMID:27666746] Sehra B,Franks RG Redundant CArG Box Cis-motif Activity Mediates SHATTERPROOF2 Transcriptional Regulation during Arabidopsis thaliana Gynoecium Development. Front Plant Sci, 2017. 8: p. 1712 [PMID:29085379] Simonini S,Stephenson P,Østergaard L A molecular framework controlling style morphology in Brassicaceae. Development, 2018. [PMID:29440299]