PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Gh_A09G0118
Common NameWRKY74
Organism
Gossypium hirsutum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family WRKY
Protein Properties Length: 521aa    MW: 56812.2 Da    PI: 7.3743
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Gh_A09G0118genomeNAU-NBIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY95.63.3e-30228285260
                  --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS-- CS
         WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhek 60 
                  +DgynWrKYGqK++kg e+prsYY+Ct+++Cpvkk versa ++ ++ei+Y+++Hnhek
  Gh_A09G0118 228 EDGYNWRKYGQKQIKGCEYPRSYYKCTHPSCPVKKIVERSA-EGLITEIIYKSTHNHEK 285
                  7****************************************.***************85 PP
2WRKY107.28.1e-34407465159
                  ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
         WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                  ldDgy+WrKYGqK+vkg+++prsYY+CtsagC+v+k+ver+++dpk+v++tYeg+Hnh+
  Gh_A09G0118 407 LDDGYRWRKYGQKVVKGNPHPRSYYKCTSAGCNVRKHVERASSDPKAVITTYEGKHNHD 465
                  59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5081122.068222286IPR003657WRKY domain
Gene3DG3DSA:2.20.25.807.8E-27223286IPR003657WRKY domain
SuperFamilySSF1182903.66E-24225286IPR003657WRKY domain
SMARTSM007741.0E-33227285IPR003657WRKY domain
PfamPF031068.9E-24228284IPR003657WRKY domain
Gene3DG3DSA:2.20.25.805.0E-37394467IPR003657WRKY domain
SuperFamilySSF1182909.94E-30399467IPR003657WRKY domain
PROSITE profilePS5081139.226402467IPR003657WRKY domain
SMARTSM007744.8E-40407466IPR003657WRKY domain
PfamPF031061.7E-26408465IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 521 aa     Download sequence    Send to blast
MAAGQGKRSK LSAPTYPTIT LPPRPPIDGL FQSGSGLSPG PMTLVSAFFS DPDSTNRSFS  60
QLLAGAMASP GAKLPYNPMD DSFMEVGFEN GGEKNSGFKQ NRPLNLGVGN SPWFTVPPGL  120
SPSGLLNSPG LFCLSPQSPF GISHQQALAQ VTAQAALVQS HVHAQPEYQT LSAAGSLEPS  180
IPPSSGNPEE TSQQMLSSDP QSSAMEYLEA SQFDKKSQPC VAVDKPTEDG YNWRKYGQKQ  240
IKGCEYPRSY YKCTHPSCPV KKIVERSAEG LITEIIYKST HNHEKPPPNK QPKGGSDGNT  300
NSQGNPELGS LAVAGNSNNL SEGKNHESTQ AVELPGFSDC EEGCDEESRE ERDDDEPNPK  360
RRQLFNLRVF RFFGCRNSTG EAAVVLSHKA VADAKIIVQT RSEVDLLDDG YRWRKYGQKV  420
VKGNPHPRSY YKCTSAGCNV RKHVERASSD PKAVITTYEG KHNHDVPAAR NSSHNTVNNS  480
LPQPKQQHDA VAEKHSLLQE IDFRNVQGPA VLRLKEEQIR V
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A1e-39228468878Probable WRKY transcription factor 4
2lex_A1e-39228468878Probable WRKY transcription factor 4
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
Ghi.203000.0boll| embryo| ovule
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: In young, mature and senescent leaves. {ECO:0000269|PubMed:11722756}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Has a positive role in resistance to necrotrophic pathogens (e.g. Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e.g. Pseudomonas syringae). {ECO:0000269|PubMed:18570649, ECO:0000269|PubMed:22219184}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By biotic and abiotic stresses such as pathogen infection (e.g. Botrytis cinerea and Pseudomonas syringae), salicylic acid (SA), jasmonic acid (JA), ethylene (ACC), liquid infiltration or spraying, and strongly during leaf senescence. {ECO:0000269|PubMed:11449049, ECO:0000269|PubMed:11722756, ECO:0000269|PubMed:18570649}.
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankFJ9668870.0FJ966887.1 Gossypium hirsutum WRKY3 transcription factor (WRKY3) mRNA, complete cds.
GenBankKF0311050.0KF031105.1 Gossypium hirsutum WRKY transcription factor 74 (WRKY74) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001313678.10.0probable WRKY transcription factor 3
SwissprotQ9XI901e-136WRKY4_ARATH; Probable WRKY transcription factor 4
TrEMBLA0A2P5WBJ90.0A0A2P5WBJ9_GOSBA; Uncharacterized protein
STRINGGorai.006G013300.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM15342792
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G13960.11e-110WRKY DNA-binding protein 4
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Aamir M, et al.
    Structural and Functional Insights into WRKY3 and WRKY4 Transcription Factors to Unravel the WRKY-DNA (W-Box) Complex Interaction in Tomato (Solanum lycopersicum L.). A Computational Approach.
    Front Plant Sci, 2017. 8: p. 819
    [PMID:28611792]