PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

EPS64487.1

Organism

Genlisea aurea

Taxonomic ID

192259

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lentibulariaceae; Genlisea

Family

Protein Properties

Length: 678aa MW: 75274.5 Da PI: 8.5821

Description

B3 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
EPS64487.1	genome	LSMU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	B3	62.3	7.9e-20	245	345	1	99
EEEE-..-HHHHTT-EE--HHH.HTT..---..--SEEEEEETTS-EEEEEE....EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SS.SEE..EE CS B3 1 ffkvltpsdvlksgrlvlpkkfaeeh..ggkkeesktltledesgrsWevkliy..rkksgryvltkGWkeFvkangLkegDfvvFkldgr.sefelvv 94 f+k+l+ sd+++ grlvlpk +ae++ ++++ e++ ++++d +g++W++++++ +++s++yvl+ G + +L++gD+v+F++ r +++lv+ EPS64487.1 245 FEKILSASDAGRIGRLVLPKACAEAYfpSINQSEGIPIKIQDVKGKEWTFQFRFwpNNNSRMYVLE-GVTPCIQNMQLQAGDTVIFSR--RdPGGQLVI 340 99************************888889999***********99899999999.*******************4..438998999 PP EEE-S CS B3 95 kvfrk 99 + +++ EPS64487.1 341 GCRKA 345 88765 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.40.330.10	3.0E-28	242	346	IPR015300	DNA-binding pseudobarrel domain
SuperFamily	SSF101936	9.42E-20	242	345	IPR015300	DNA-binding pseudobarrel domain
CDD	cd10017	2.36E-23	243	344	No hit	No description
Pfam	PF02362	1.1E-16	245	344	IPR003340	B3 DNA binding domain
PROSITE profile	PS50863	11.011	245	346	IPR003340	B3 DNA binding domain
SMART	SM01019	1.9E-20	245	345	IPR003340	B3 DNA binding domain
PROSITE profile	PS51050	13.077	477	527	IPR011124	Zinc finger, CW-type
Pfam	PF07496	3.6E-11	484	524	IPR011124	Zinc finger, CW-type

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010030	Biological Process	positive regulation of seed germination
GO:0045892	Biological Process	negative regulation of transcription, DNA-templated
GO:2000034	Biological Process	regulation of seed maturation
GO:0005634	Cellular Component	nucleus
GO:0005739	Cellular Component	mitochondrion
GO:0016021	Cellular Component	integral component of membrane
GO:0003677	Molecular Function	DNA binding
GO:0008270	Molecular Function	zinc ion binding

Sequence ? help Back to Top
Protein Sequence Length: 678 aa Download sequence Send to blast
AYENSIFCET FHSEESGWRE CKFCGKLVHC GCIASRYLYE FMDFGGIGCG SCAKRIELQS 60 GQTLQVVIHI YADGRSFSSF FFVVVVLSNA IGITSITSAF EQHKLENEKQ RMTGLSEPYT 120 PSIFLGNRAK QGPKNIYETL AHSPLNFSLS SPSSNSALPF HGKIGEGSEP SSKASFKARL 180 PKLPKQSILS GGETNKGSGS QGRVPRPPAE IRGRNQLLPR YWPRITDQEL QQLSGDLKST 240 IVPLFEKILS ASDAGRIGRL VLPKACAEAY FPSINQSEGI PIKIQDVKGK EWTFQFRFWP 300 NNNSRMYVLE GVTPCIQNMQ LQAGDTVIFS RRDPGGQLVI GCRKATNKFE LPVIFFRKKK 360 LTVTSFAKDP LSPAVLHGDA STEALLTSSA DKLPSVSGED SPRHTEKKKS KNIKNKRLLM 420 HNDDAVELRI TWEEAQELFR PSSSVQPTVV LVEGHEFEEF EEPPLFGKRT VFISQPSGEQ 480 EQLAQCDNCF KWRRLPANAL LVANWTCSNN IWDSSRCSCS VPEEMNPRDL DFRGGVSYDN 540 KKQRNSDAKV ASEMEEPTGL EALATAAVLG DNVDVGESSA SATTRHPRHR PGCSCIVCIQ 600 PPSGKGKHEP TCKCNVCLTV RRRFKTLMMR KKKRQAEDPP PQQQPQNASK ASRVESRNES 660 EEAVVGKKSS QLDLNCDP

Sequence ? help Back to Top

Protein Sequence Length: 678 aa Download sequence Send to blast

AYENSIFCET FHSEESGWRE CKFCGKLVHC GCIASRYLYE FMDFGGIGCG SCAKRIELQS  60
GQTLQVVIHI YADGRSFSSF FFVVVVLSNA IGITSITSAF EQHKLENEKQ RMTGLSEPYT  120
PSIFLGNRAK QGPKNIYETL AHSPLNFSLS SPSSNSALPF HGKIGEGSEP SSKASFKARL  180
PKLPKQSILS GGETNKGSGS QGRVPRPPAE IRGRNQLLPR YWPRITDQEL QQLSGDLKST  240
IVPLFEKILS ASDAGRIGRL VLPKACAEAY FPSINQSEGI PIKIQDVKGK EWTFQFRFWP  300
NNNSRMYVLE GVTPCIQNMQ LQAGDTVIFS RRDPGGQLVI GCRKATNKFE LPVIFFRKKK  360
LTVTSFAKDP LSPAVLHGDA STEALLTSSA DKLPSVSGED SPRHTEKKKS KNIKNKRLLM  420
HNDDAVELRI TWEEAQELFR PSSSVQPTVV LVEGHEFEEF EEPPLFGKRT VFISQPSGEQ  480
EQLAQCDNCF KWRRLPANAL LVANWTCSNN IWDSSRCSCS VPEEMNPRDL DFRGGVSYDN  540
KKQRNSDAKV ASEMEEPTGL EALATAAVLG DNVDVGESSA SATTRHPRHR PGCSCIVCIQ  600
PPSGKGKHEP TCKCNVCLTV RRRFKTLMMR KKKRQAEDPP PQQQPQNASK ASRVESRNES  660
EEAVVGKKSS QLDLNCDP

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
6j9a_A	4e-68	223	351	2	130	B3 domain-containing transcription repressor VAL1
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	620	631	RRRFKTLMMRKK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor of gene expression involved in embryonic pathways, such as LEC1, ABI3, and FUS3. Repressor of the sugar-inducible genes involved in the seed maturation program in seedlings. Plays an essential role in regulating the transition from seed maturation to seedling growth. Functionally redundant with VAL2/HSL1. {ECO:0000269\|PubMed:15894743, ECO:0000269\|PubMed:17158584, ECO:0000269\|PubMed:17267611}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012841792.1	0.0	PREDICTED: B3 domain-containing transcription repressor VAL1-like
Swissprot	Q8W4L5	0.0	VAL1_ARATH; B3 domain-containing transcription repressor VAL1
TrEMBL	S8DX33	0.0	S8DX33_9LAMI; Uncharacterized protein (Fragment)
STRING	Migut.D00818.1.p	0.0	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1491	23	65

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G30470.1	1e-172	high-level expression of sugar-inducible gene 2

Publications ? help Back to Top
Leushkin EV, et al. The miniature genome of a carnivorous plant Genlisea aurea contains a low number of genes and short non-coding sequences. BMC Genomics, 2013. 14: p. 476 [PMID:23855885] Jia H,McCarty DR,Suzuki M Distinct roles of LAFL network genes in promoting the embryonic seedling fate in the absence of VAL repression. Plant Physiol., 2013. 163(3): p. 1293-305 [PMID:24043445] Schneider A, et al. Potential targets of VIVIPAROUS1/ABI3-LIKE1 (VAL1) repression in developing Arabidopsis thaliana embryos. Plant J., 2016. 85(2): p. 305-19 [PMID:26678037] Chhun T, et al. HSI2 Repressor Recruits MED13 and HDA6 to Down-Regulate Seed Maturation Gene Expression Directly During Arabidopsis Early Seedling Growth. Plant Cell Physiol., 2016. 57(8): p. 1689-706 [PMID:27335347] Qüesta JI,Song J,Geraldo N,An H,Dean C Arabidopsis transcriptional repressor VAL1 triggers Polycomb silencing at FLC during vernalization. Science, 2016. 353(6298): p. 485-8 [PMID:27471304] Yuan W, et al. A cis cold memory element and a trans epigenome reader mediate Polycomb silencing of FLC by vernalization in Arabidopsis. Nat. Genet., 2016. 48(12): p. 1527-1534 [PMID:27819666] Merini W, et al. The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development. Plant Physiol., 2017. 173(1): p. 627-641 [PMID:27837089] Li C,Cui Y A DNA element that remembers winter. Nat. Genet., 2016. 48(12): p. 1451-1452 [PMID:27898079] Chen N,Veerappan V,Abdelmageed H,Kang M,Allen RD HSI2/VAL1 Silences AGL15 to Regulate the Developmental Transition from Seed Maturation to Vegetative Growth in Arabidopsis. Plant Cell, 2018. 30(3): p. 600-619 [PMID:29475938] Sasnauskas G,Kauneckaite K,Siksnys V Structural basis of DNA target recognition by the B3 domain of Arabidopsis epigenome reader VAL1. Nucleic Acids Res., 2018. 46(8): p. 4316-4324 [PMID:29660015] Wu B, et al. Structural insight into the role of VAL1 B3 domain for targeting to FLC locus in Arabidopsis thaliana. Biochem. Biophys. Res. Commun., 2018. 501(2): p. 415-422 [PMID:29733847]