PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID EPS60924.1
Organism
Genlisea aurea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lentibulariaceae; Genlisea
Family bHLH
Protein Properties Length: 539aa    MW: 59630.9 Da    PI: 6.959
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
EPS60924.1genomeLSMUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH39.79e-13362407454
                 HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
         HLH   4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                 +h e+Er+RR+++N++f  Lr ++P+       K++Ka+ L  A+ YI++L
  EPS60924.1 362 NHVEAERQRREKLNQKFYALRAVVPNV-----SKMDKASLLGDAISYINEL 407
                 799***********************6.....5***************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142152.0E-477190IPR025610Transcription factor MYC/MYB N-terminal
SuperFamilySSF1014479.68E-6196206No hitNo description
PROSITE profilePS5088817.25358407IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.07E-18359429IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.40E-15361412No hitNo description
Gene3DG3DSA:4.10.280.108.7E-19362429IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000102.9E-10362407IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003537.7E-17364413IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 539 aa     Download sequence    Send to blast
MLSQENLQKR LISLIDGARE SWTYAIFWQN SAADGGCNFF PGVLSWGDGY YRGEDGGDNR  60
RRKTTSSPAE QEQRKEVLRE LSSLVSGGYP SSSAGDAVNE DVTDAEWFFL ISMTQTFHGG  120
IGIPGQASGT VWITGPERLA EAGCDRARQA LSHGIRTMAY IPVFNGVVEF GSTAVIFQNL  180
DLVKKVKSLF NFDASPPPPP PPPPPPVPGT TGFEFLSRRD LNFSDFRFNS SNNSSTMTMM  240
RNIGNSPCKH QSGEILNFGD NTAQMDNYFS SVVQADSDAI RAKKRYPTSK GSSNEGGGLS  300
FTSVVIAPSS SATLKADKVE SDHSDMEASV VKEAESSRAA LPERRPRKRG RKPANGREEP  360
LNHVEAERQR REKLNQKFYA LRAVVPNVSK MDKASLLGDA ISYINELRTQ LQNSEMDMQD  420
LKSQIESLNN HHHLPLPHES KRPRKCEEGE SFTATGEDAV DIEVKIIGRD DAMIRIQCSK  480
KNHPAAKLMT AFRELDLDLH HASLSVANEF MIQQATVKMG SRYFSQDQLR LALMSKIAE
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4rqw_A1e-4821934195Transcription factor MYC3
4rqw_B1e-4821934195Transcription factor MYC3
4rs9_A1e-4821934195Transcription factor MYC3
4yz6_A1e-4821934195Transcription factor MYC3
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1343351RRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds to the G-box motif (5'-AACGTG-3') found in the promoter of the jasmonate-induced gene LAPA1 (PubMed:15231736). Acts as negative regulator of blue light-mediated photomorphogenesis and positively regulates root growth (PubMed:24483714). Promotes growth in response to the phytohormones abscisic acid (ABA) and jasmonate (JA) (PubMed:24483714). Binds to the G-box motif (5'-CACGTG-3') of the RBCS-3A gene promoter (PubMed:24483714). Acts downstream of the jasmonate (JA) receptor to orchestrate JA-mediated activation of plant responses (PubMed:28733419). Positively regulates both wound-responsive and pathogen-responsive genes through MYC2-targeted transcription factors (MTFs) involved in early response to JA (PubMed:28733419). With JA2L forms a transcription module that regulates wounding-responsive genes (PubMed:28733419). With ERF.C3 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). Plays a critical role in orchestrating JA-mediated defense gene expression during Botrytis cinerea infection (PubMed:28733419). Regulates negatively defense responses to root-knot nematodes, potentially by mediating crosstalk among the hormones strigolactones, abscisic acid (ABA) and jasmonate (JA) (PubMed:30576511). Regulates the termination of JA-mediated defense responses by specifically binding the G-box (5'-CACATG-3') motifs in the promoters of MTB1, MTB2 and MTB3, which are transcription factors that negatively regulates JA signaling (PubMed:30610166). May be involved in JA-induced chilling tolerance, possibly by ameliorating the antioxidant enzyme system of fruit and increasing proline and lycopene levels (PubMed:29528226). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:24483714, ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:29528226, ECO:0000269|PubMed:30576511, ECO:0000269|PubMed:30610166}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by methyl jasmonate (PubMed:15231736, PubMed:28733419). Induced by wounding (PubMed:15231736). Induced by infection with the fungal pathogen Botrytis cinerea (PubMed:28733419). Induced in fruit by storage in cold (PubMed:29528226). Induced by hydrogen peroxide and infection with root-knot nematodes (PubMed:30576511). {ECO:0000269|PubMed:15231736, ECO:0000269|PubMed:28733419, ECO:0000269|PubMed:29528226, ECO:0000269|PubMed:30576511}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016500373.10.0PREDICTED: transcription factor MYC2-like
SwissprotA0A3Q7HRZ60.0MYC2_SOLLC; Transcription factor MYC2
TrEMBLS8C2N10.0S8C2N1_9LAMI; Uncharacterized protein (Fragment)
STRINGXP_009780487.10.0(Nicotiana sylvestris)
STRINGXP_009609942.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA33002449
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G17880.14e-80bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Leushkin EV, et al.
    The miniature genome of a carnivorous plant Genlisea aurea contains a low number of genes and short non-coding sequences.
    BMC Genomics, 2013. 14: p. 476
    [PMID:23855885]
  3. Gupta N,Prasad VB,Chattopadhyay S
    LeMYC2 acts as a negative regulator of blue light mediated photomorphogenic growth, and promotes the growth of adult tomato plants.
    BMC Plant Biol., 2014. 14: p. 38
    [PMID:24483714]
  4. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  5. Du M, et al.
    MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato.
    Plant Cell, 2017. 29(8): p. 1883-1906
    [PMID:28733419]
  6. Min D, et al.
    SlMYC2 Involved in Methyl Jasmonate-Induced Tomato Fruit Chilling Tolerance.
    J. Agric. Food Chem., 2018. 66(12): p. 3110-3117
    [PMID:29528226]
  7. Xu X, et al.
    Strigolactones positively regulate defense against root-knot nematodes in tomato.
    J. Exp. Bot., 2019. 70(4): p. 1325-1337
    [PMID:30576511]
  8. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]