PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

EPS57820.1

Organism

Genlisea aurea

Taxonomic ID

192259

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lentibulariaceae; Genlisea

Family

bHLH

Protein Properties

Length: 562aa MW: 61443.3 Da PI: 5.3166

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
EPS57820.1	genome	LSMU	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	39.4	1e-12	395	440	4	54
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 +h e+Er+RR+++N++f Lr ++P+ K++Ka+ L A+ YI++L EPS57820.1 395 NHVEAERQRREKLNQRFYALRAVVPNV-----SKMDKASLLGDAISYINEL 440 799*********************6.....5*************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	1.1E-52	4	188	IPR025610	Transcription factor MYC/MYB N-terminal
PROSITE profile	PS50888	17.39	391	440	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	3.27E-19	392	466	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.52E-15	394	445	No hit	No description
Gene3D	G3DSA:4.10.280.10	2.0E-19	395	462	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	3.4E-10	395	440	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.4E-16	397	446	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006952	Biological Process	defense response
GO:0009718	Biological Process	anthocyanin-containing compound biosynthetic process
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0043425	Molecular Function	bHLH transcription factor binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 562 aa Download sequence Send to blast
QENLQQRLSA LIDGARECWT YAIFWQNSAA DFGLPPSALS WGDGYYKGEE DKEKRKTASS 60 YAEQEHRKKV LRELNSLVSG QQASSPDDDG AAVDEEVTDT EWFFLISMTQ TFENGSGIPG 120 QAMFASSPVW VAGPERLAEA NCDRARQALG YGLRTLVCIP SSNGVVELGS TSVIFQSSDL 180 VRKVKSLFNF NCTDDASVSG TGSWGTGDGD PAALWLTDHP SSSGVEAKQQ MVFGNENPKS 240 MADNSIFLSS RDLNFSDFRF GGSIAATMKN TAPPCKPESG EILNFGEATS TKTNLFTPQP 300 DNNNTTVSKT KKRSPQSRGS NEEGILSFTS AVIAPSSSGI PKTDNTGGCN VESDDHSDLE 360 ASIVKGADSS RVFDPEKRPR KRGRKPANGR EEPLNHVEAE RQRREKLNQR FYALRAVVPN 420 VSKMDKASLL GDAISYINEL KSKLQNSEMD VDELRSQLES LKKEHNDSDP PTGYTTASAT 480 NNVSVDIEVK IIGRDAMIQV QCGKRNHPAA QLMTAFRELD LDVHHASVSV VNELMIQQAT 540 VKMGSKYFTQ DHLRLALMSK LA

Sequence ? help Back to Top

Protein Sequence Length: 562 aa Download sequence Send to blast

QENLQQRLSA LIDGARECWT YAIFWQNSAA DFGLPPSALS WGDGYYKGEE DKEKRKTASS  60
YAEQEHRKKV LRELNSLVSG QQASSPDDDG AAVDEEVTDT EWFFLISMTQ TFENGSGIPG  120
QAMFASSPVW VAGPERLAEA NCDRARQALG YGLRTLVCIP SSNGVVELGS TSVIFQSSDL  180
VRKVKSLFNF NCTDDASVSG TGSWGTGDGD PAALWLTDHP SSSGVEAKQQ MVFGNENPKS  240
MADNSIFLSS RDLNFSDFRF GGSIAATMKN TAPPCKPESG EILNFGEATS TKTNLFTPQP  300
DNNNTTVSKT KKRSPQSRGS NEEGILSFTS AVIAPSSSGI PKTDNTGGCN VESDDHSDLE  360
ASIVKGADSS RVFDPEKRPR KRGRKPANGR EEPLNHVEAE RQRREKLNQR FYALRAVVPN  420
VSKMDKASLL GDAISYINEL KSKLQNSEMD VDELRSQLES LKKEHNDSDP PTGYTTASAT  480
NNVSVDIEVK IIGRDAMIQV QCGKRNHPAA QLMTAFRELD LDVHHASVSV VNELMIQQAT  540
VKMGSKYFTQ DHLRLALMSK LA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4rqw_A	2e-62	1	191	6	195	Transcription factor MYC3
4rqw_B	2e-62	1	191	6	195	Transcription factor MYC3
4rs9_A	2e-62	1	191	6	195	Transcription factor MYC3
4yz6_A	2e-62	1	191	6	195	Transcription factor MYC3
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Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	376	384	KRPRKRGRK

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator that binds to the G-box motif (5'-AACGTG-3') found in the promoter of the jasmonate-induced gene LAPA1 (PubMed:15231736). Acts as negative regulator of blue light-mediated photomorphogenesis and positively regulates root growth (PubMed:24483714). Promotes growth in response to the phytohormones abscisic acid (ABA) and jasmonate (JA) (PubMed:24483714). Binds to the G-box motif (5'-CACGTG-3') of the RBCS-3A gene promoter (PubMed:24483714). Acts downstream of the jasmonate (JA) receptor to orchestrate JA-mediated activation of plant responses (PubMed:28733419). Positively regulates both wound-responsive and pathogen-responsive genes through MYC2-targeted transcription factors (MTFs) involved in early response to JA (PubMed:28733419). With JA2L forms a transcription module that regulates wounding-responsive genes (PubMed:28733419). With ERF.C3 forms a transcription module that regulates pathogen-responsive genes (PubMed:28733419). Plays a critical role in orchestrating JA-mediated defense gene expression during Botrytis cinerea infection (PubMed:28733419). Regulates negatively defense responses to root-knot nematodes, potentially by mediating crosstalk among the hormones strigolactones, abscisic acid (ABA) and jasmonate (JA) (PubMed:30576511). Regulates the termination of JA-mediated defense responses by specifically binding the G-box (5'-CACATG-3') motifs in the promoters of MTB1, MTB2 and MTB3, which are transcription factors that negatively regulates JA signaling (PubMed:30610166). May be involved in JA-induced chilling tolerance, possibly by ameliorating the antioxidant enzyme system of fruit and increasing proline and lycopene levels (PubMed:29528226). {ECO:0000269\|PubMed:15231736, ECO:0000269\|PubMed:24483714, ECO:0000269\|PubMed:28733419, ECO:0000269\|PubMed:29528226, ECO:0000269\|PubMed:30576511, ECO:0000269\|PubMed:30610166}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00086	PBM	Transfer from AT4G17880	Download

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced by methyl jasmonate (PubMed:15231736, PubMed:28733419). Induced by wounding (PubMed:15231736). Induced by infection with the fungal pathogen Botrytis cinerea (PubMed:28733419). Induced in fruit by storage in cold (PubMed:29528226). Induced by hydrogen peroxide and infection with root-knot nematodes (PubMed:30576511). {ECO:0000269\|PubMed:15231736, ECO:0000269\|PubMed:28733419, ECO:0000269\|PubMed:29528226, ECO:0000269\|PubMed:30576511}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011082365.1	0.0	transcription factor MYC4-like
Swissprot	A0A3Q7HRZ6	0.0	MYC2_SOLLC; Transcription factor MYC2
TrEMBL	S8BT83	0.0	S8BT83_9LAMI; Uncharacterized protein (Fragment)
STRING	XP_009609942.1	0.0	(Nicotiana tomentosiformis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA3300	24	49

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G17880.1	1e-161	bHLH family protein

Publications ? help Back to Top
Tomato Genome Consortium The tomato genome sequence provides insights into fleshy fruit evolution. Nature, 2012. 485(7400): p. 635-41 [PMID:22660326] Leushkin EV, et al. The miniature genome of a carnivorous plant Genlisea aurea contains a low number of genes and short non-coding sequences. BMC Genomics, 2013. 14: p. 476 [PMID:23855885] Gupta N,Prasad VB,Chattopadhyay S LeMYC2 acts as a negative regulator of blue light mediated photomorphogenic growth, and promotes the growth of adult tomato plants. BMC Plant Biol., 2014. 14: p. 38 [PMID:24483714] Sun H,Fan HJ,Ling HQ Genome-wide identification and characterization of the bHLH gene family in tomato. BMC Genomics, 2015. 16: p. 9 [PMID:25612924] Du M, et al. MYC2 Orchestrates a Hierarchical Transcriptional Cascade That Regulates Jasmonate-Mediated Plant Immunity in Tomato. Plant Cell, 2017. 29(8): p. 1883-1906 [PMID:28733419] Min D, et al. SlMYC2 Involved in Methyl Jasmonate-Induced Tomato Fruit Chilling Tolerance. J. Agric. Food Chem., 2018. 66(12): p. 3110-3117 [PMID:29528226] Xu X, et al. Strigolactones positively regulate defense against root-knot nematodes in tomato. J. Exp. Bot., 2019. 70(4): p. 1325-1337 [PMID:30576511] Liu Y, et al. MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop. Plant Cell, 2019. 31(1): p. 106-127 [PMID:30610166]