PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID EPS57394.1
Organism
Genlisea aurea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lentibulariaceae; Genlisea
Family HD-ZIP
Protein Properties Length: 328aa    MW: 36694.5 Da    PI: 6.5164
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
EPS57394.1genomeLSMUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox63.82.5e-203085156
                TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
    Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                ++k +++t++q+++Le++F+ +++p++++r  L+++lgL  rqVk+WFqNrR++ k
  EPS57394.1 30 KKKYHRHTADQIQRLEQMFRDCPHPDEKTRSLLSRELGLHPRQVKFWFQNRRTQIK 85
                79999***********************************************9877 PP
2START36.99.2e-13230324288
                 HHHHHHHHHHHHHHHC-TT-EEEE..EXCCTTEEEEEEESSS....SCEEEEEEEECCSCHHHHHHHHHCCCGGCT-TT-S....EEEEEEEECTT CS
       START   2 laeeaaqelvkkalaeepgWvkss..esengdevlqkfeeskv...dsgealrasgvvdmvlallveellddkeqWdetla....kaetlevissg 88 
                 +a +a++el++ ++ +ep+W  s   e++n +++ + f++ +     ++ea+r+sgvv m+   lv +++d + +W e ++    +a t+evissg
  EPS57394.1 230 YASRALEELIRVMQNNEPLWIASEnrEMLNLETYDRMFPRPNKnpnLRSEASRDSGVVLMNGLALVDTFMDAN-KWMELFPtivsRARTMEVISSG 324
                 7899********************9999999998888887666789***************************.**999999999*********99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF466897.1E-201487IPR009057Homeodomain-like
Gene3DG3DSA:1.10.10.601.1E-211989IPR009057Homeodomain-like
PROSITE profilePS5007117.1352787IPR001356Homeobox domain
SMARTSM003891.6E-182991IPR001356Homeobox domain
CDDcd000867.89E-183088No hitNo description
PfamPF000469.7E-183085IPR001356Homeobox domain
PROSITE patternPS0002706285IPR017970Homeobox, conserved site
PROSITE profilePS5084819.041220328IPR002913START domain
SuperFamilySSF559617.51E-7222324No hitNo description
PfamPF018525.1E-7230324IPR002913START domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0008289Molecular Functionlipid binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 328 aa     Download sequence    Send to blast
MEFSGGGGGG GGGGSVGGDN QDVSDPHQRK KKYHRHTADQ IQRLEQMFRD CPHPDEKTRS  60
LLSRELGLHP RQVKFWFQNR RTQIKAQHER ADNCALRAEN DKIRCENIAI REALKNIICP  120
TCGGPPVTED SYFDEQKLRM ENAQLKQELD RLSSVAAKYM GRPISQLPPM QSLHFSSLDL  180
SMATSFNGHG ISGPSLDLDL LPGSSSSVVT DLPFPPMSLS EVDKSIMAEY ASRALEELIR  240
VMQNNEPLWI ASENREMLNL ETYDRMFPRP NKNPNLRSEA SRDSGVVLMN GLALVDTFMD  300
ANKWMELFPT IVSRARTMEV ISSGQSGT
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1314SGGGGGGGGGGS
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011072039.11e-179homeobox-leucine zipper protein HDG11
SwissprotQ9FX311e-134HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLS8BSP90.0S8BSP9_9LAMI; Uncharacterized protein (Fragment)
STRINGMigut.O00242.1.p1e-169(Erythranthe guttata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA24902351
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.11e-126homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Leushkin EV, et al.
    The miniature genome of a carnivorous plant Genlisea aurea contains a low number of genes and short non-coding sequences.
    BMC Genomics, 2013. 14: p. 476
    [PMID:23855885]
  3. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  4. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  5. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  6. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  7. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  8. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  9. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  10. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  11. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]