PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Cotton_A_37863_BGI-A2_v1.0 | ||||||||
Common Name | F383_33638 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
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Family | E2F/DP | ||||||||
Protein Properties | Length: 385aa MW: 43586 Da PI: 9.8594 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 73.6 | 2e-23 | 21 | 86 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rk+ksL+ll+++fl++++k + + l+e+a +L v +rRRiYDi+NVLe+++++++k+kn+++wkg Cotton_A_37863_BGI-A2_v1.0 21 RKQKSLGLLCSNFLSMYNKDGIEFIGLDEAAARL---GV--ERRRIYDIVNVLESVGVLTRKAKNKYTWKG 86 79*****************999************...**..****************************98 PP | |||||||
2 | E2F_TDP | 75.6 | 4.9e-24 | 158 | 238 | 1 | 71 |
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 r+eksL+lltq+f+kl+ +s+++ ++l+e+a+ L+ + +++k+RR+YDi+NVL+++ liek ++k+++rw g Cotton_A_37863_BGI-A2_v1.0 158 RREKSLGLLTQNFVKLFLCSSAELISLDEAARLLLGNahntsVMRTKVRRLYDIANVLSSMSLIEKthtvdTRKPAFRWLG 238 689*******************************9999*99999***********************************87 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
Gene3D | G3DSA:1.10.10.10 | 7.7E-26 | 17 | 87 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SuperFamily | SSF46785 | 4.16E-16 | 20 | 84 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 9.5E-27 | 21 | 86 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 4.8E-20 | 22 | 86 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 4.7E-23 | 156 | 239 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
SMART | SM01372 | 1.7E-31 | 158 | 238 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Pfam | PF02319 | 3.4E-19 | 160 | 238 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 3.32E-13 | 160 | 239 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0032876 | Biological Process | negative regulation of DNA endoreduplication | ||||
GO:0005634 | Cellular Component | nucleus | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003677 | Molecular Function | DNA binding | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 385 aa Download sequence Send to blast |
MPVSSSSSLP ESSSRHYTYS RKQKSLGLLC SNFLSMYNKD GIEFIGLDEA AARLGVERRR 60 IYDIVNVLES VGVLTRKAKN KYTWKGFGAI PKALQNLKEE GFSSNFKKFD VHNIAKVSDD 120 DDDDEEDERF FNPITGSQTE TSKSTSILKS SSVKVDNRRE KSLGLLTQNF VKLFLCSSAE 180 LISLDEAARL LLGNAHNTSV MRTKVRRLYD IANVLSSMSL IEKTHTVDTR KPAFRWLGLR 240 GKSEKGSADA LVLNESRKRA FGTDVTNVSF KKNKVDSSND QNFNKSQQKH KKVENLVPAD 300 DRSRLEDSKQ ASKSYEFGPF APVNLTKIRN SENDAKPVYD WESLASTYRP QYHNQALRDL 360 FSHYMEAWKS WYSEVAGKTP IIQIS |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
4yo2_A | 6e-41 | 20 | 230 | 3 | 228 | Transcription factor E2F8 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}. |
Binding Motif ? help Back to Top | |||
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Motif ID | Method | Source | Motif file |
MP00397 | DAP | Transfer from AT3G48160 | Download |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_017625312.1 | 0.0 | PREDICTED: E2F transcription factor-like E2FE | ||||
Swissprot | Q8LSZ4 | 1e-140 | E2FE_ARATH; E2F transcription factor-like E2FE | ||||
TrEMBL | A0A0B0MXW0 | 0.0 | A0A0B0MXW0_GOSAR; E2F transcription factor-like E2FE | ||||
STRING | Gorai.004G114000.1 | 0.0 | (Gossypium raimondii) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM6304 | 27 | 43 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT3G48160.2 | 1e-135 | DP-E2F-like 1 |
Publications ? help Back to Top | |||
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