PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cotton_A_26439_BGI-A2_v1.0
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family ARR-B
Protein Properties Length: 420aa    MW: 46915.4 Da    PI: 5.469
Description ARR-B family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cotton_A_26439_BGI-A2_v1.0genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1G2-like75.38.5e-24182239156
                     G2-like   1 kprlrWtpeLHerFveaveqLGGsekAtPkti...lelmkvkgLtlehvkSHLQkYRla 56 
                                 kpr++Wt+eLH+ Fv av++L G  +A+Pk+i   +++m+v  Lt+++++SHLQkYR++
  Cotton_A_26439_BGI-A2_v1.0 182 KPRMVWTQELHDLFVAAVNEL-GRGNAVPKKIlerMQAMNVTFLTRANIASHLQKYRMH 239
                                 79*******************.9*********3333578999***************96 PP

2Response_reg76.11.3e-25131191107
                                 EEEESSSHHHHHHHHHHHHHTTCEEEEEESSHHHHHHHHHHHH..ESEEEEESSCTTSEHHHHHHHHHHHTTTSEEEEEESTT CS
                Response_reg   1 vlivdDeplvrellrqalekegyeevaeaddgeealellkekd..pDlillDiempgmdGlellkeireeepklpiivvtahg 81 
                                 +livdD+++ + +l+++l+k  y +v+ +++++eal+ll++ +  +D++l+D+ mp+++G+ell+ i+ e  +lp++++++ +
  Cotton_A_26439_BGI-A2_v1.0  13 ILIVDDDRTCLLVLERMLRKFSY-QVTKCQQAREALALLRQDKnrFDIVLCDLHMPDINGFELLQIIEVEM-DLPVVMMSSDD 93 
                                 8**********************.***************777778**********************8755.9********** PP

                                 THHHHHHHHHTTESEEEESS--HHHH CS
                Response_reg  82 eeedalealkaGakdflsKpfdpeel 107
                                  +  + + +  Ga d+l+Kp+ +e++
  Cotton_A_26439_BGI-A2_v1.0  94 GKGVVMKGIVHGACDYLVKPVRMEAI 119
                                 ********************998876 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.40.50.23002.9E-3810153No hitNo description
SuperFamilySSF521726.55E-3410132IPR011006CheY-like superfamily
SMARTSM004481.7E-2811123IPR001789Signal transduction response regulator, receiver domain
PROSITE profilePS5011041.14912127IPR001789Signal transduction response regulator, receiver domain
PfamPF000729.7E-2313119IPR001789Signal transduction response regulator, receiver domain
CDDcd001561.86E-2614119No hitNo description
PROSITE profilePS5129410.376179241IPR017930Myb domain
Gene3DG3DSA:1.10.10.602.5E-24181242IPR009057Homeodomain-like
SuperFamilySSF466892.87E-17181242IPR009057Homeodomain-like
TIGRFAMsTIGR015572.7E-21182239IPR006447Myb domain, plants
PfamPF002492.4E-8184237IPR001005SANT/Myb domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0000160Biological Processphosphorelay signal transduction system
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 420 aa     Download sequence    Send to blast
MTMAGEFPAG LKILIVDDDR TCLLVLERML RKFSYQVTKC QQAREALALL RQDKNRFDIV  60
LCDLHMPDIN GFELLQIIEV EMDLPVVMMS SDDGKGVVMK GIVHGACDYL VKPVRMEAIG  120
LIWQHVVRKK KKRFSGEITR SLPLQPADNA VPPMDKRSLK YRKRTSEDED VAEDGESSEG  180
KKPRMVWTQE LHDLFVAAVN ELGRGNAVPK KILERMQAMN VTFLTRANIA SHLQKYRMHL  240
QKEGPVPSSD SRDVNAYIDH RNLQFQPSPT TPYQLPMQNL ITERANGNVL SIAPSHVDGG  300
SNIFNSNIAS ESSCSLPTQV TLYNLYRANL LYQNDFPPTS NGVAISNDNA FPPNDGVANS  360
NDESFYCNVV DGTELSNPFS AVAVDGTELS NPLSAVEELI HEPSFLVGQY DQQAFFRGPI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1irz_A1e-16181242462ARR10-B
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1127132RKKKKR
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'. Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Could directly activate some type-A response regulators in response to cytokinins. Regulates SHY2 by binding to its promoter (PubMed:19039136). Involved in the root-meristem size determination through the regulation of cell differentiation (PubMed:17363254). {ECO:0000269|PubMed:11574878, ECO:0000269|PubMed:11691951, ECO:0000269|PubMed:17363254, ECO:0000269|PubMed:19039136}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Down-regulated by gibberellin. {ECO:0000269|PubMed:20605455}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017628557.10.0PREDICTED: two-component response regulator ARR2-like
SwissprotQ940D05e-81ARR1_ARATH; Two-component response regulator ARR1
TrEMBLA0A1U8L2J50.0A0A1U8L2J5_GOSHI; two-component response regulator ARR2-like isoform X1
STRINGGorai.007G125800.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM2484834
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G16857.19e-84response regulator 1
Publications ? help Back to Top
  1. Bürkle L,Meyer S,Dortay H,Lehrach H,Heyl A
    In vitro recombination cloning of entire cDNA libraries in Arabidopsis thaliana and its application to the yeast two-hybrid system.
    Funct. Integr. Genomics, 2005. 5(3): p. 175-83
    [PMID:15714319]
  2. Moubayidin L, et al.
    Spatial coordination between stem cell activity and cell differentiation in the root meristem.
    Dev. Cell, 2013. 26(4): p. 405-15
    [PMID:23987513]
  3. Takahashi N, et al.
    Cytokinins control endocycle onset by promoting the expression of an APC/C activator in Arabidopsis roots.
    Curr. Biol., 2013. 23(18): p. 1812-7
    [PMID:24035544]
  4. Kurepa J,Li Y,Perry SE,Smalle JA
    Ectopic expression of the phosphomimic mutant version of Arabidopsis response regulator 1 promotes a constitutive cytokinin response phenotype.
    BMC Plant Biol., 2014. 14: p. 28
    [PMID:24423196]
  5. Cortleven A, et al.
    A novel protective function for cytokinin in the light stress response is mediated by the Arabidopsis histidine kinase2 and Arabidopsis histidine kinase3 receptors.
    Plant Physiol., 2014. 164(3): p. 1470-83
    [PMID:24424319]
  6. Marín-de la Rosa N, et al.
    Genome Wide Binding Site Analysis Reveals Transcriptional Coactivation of Cytokinin-Responsive Genes by DELLA Proteins.
    PLoS Genet., 2015. 11(7): p. e1005337
    [PMID:26134422]
  7. D'Alessandro S,Golin S,Hardtke CS,Lo Schiavo F,Zottini M
    The co-chaperone p23 controls root development through the modulation of auxin distribution in the Arabidopsis root meristem.
    J. Exp. Bot., 2015. 66(16): p. 5113-22
    [PMID:26163704]
  8. Jiang L, et al.
    Strigolactones spatially influence lateral root development through the cytokinin signaling network.
    J. Exp. Bot., 2016. 67(1): p. 379-89
    [PMID:26519957]
  9. Moubayidin L, et al.
    A SCARECROW-based regulatory circuit controls Arabidopsis thaliana meristem size from the root endodermis.
    Planta, 2016. 243(5): p. 1159-68
    [PMID:26848984]
  10. Muraro D, et al.
    A multi-scale model of the interplay between cell signalling and hormone transport in specifying the root meristem of Arabidopsis thaliana.
    J. Theor. Biol., 2016. 404: p. 182-205
    [PMID:27157127]
  11. Cortleven A, et al.
    Cytokinin Regulates the Etioplast-Chloroplast Transition through the Two-Component Signaling System and Activation of Chloroplast-Related Genes.
    Plant Physiol., 2016. 172(1): p. 464-78
    [PMID:27388681]
  12. Kobayashi K, et al.
    Shoot Removal Induces Chloroplast Development in Roots via Cytokinin Signaling.
    Plant Physiol., 2017. 173(4): p. 2340-2355
    [PMID:28193764]
  13. Zhang TQ, et al.
    A Two-Step Model for de Novo Activation of WUSCHEL during Plant Shoot Regeneration.
    Plant Cell, 2017. 29(5): p. 1073-1087
    [PMID:28389585]
  14. Kushwah S,Laxmi A
    The interaction between glucose and cytokinin signaling in controlling Arabidopsis thaliana seedling root growth and development.
    Plant Signal Behav, 2017. 12(5): p. e1312241
    [PMID:28467152]
  15. Meng WJ, et al.
    Type-B ARABIDOPSIS RESPONSE REGULATORs Specify the Shoot Stem Cell Niche by Dual Regulation of WUSCHEL.
    Plant Cell, 2017. 29(6): p. 1357-1372
    [PMID:28576846]
  16. Kobayashi K,Iwase A
    Simultaneous but spatially different regulation of non-photosynthetic callus formation and photosynthetic root development after shoot removal.
    Plant Signal Behav, 2017. 12(6): p. e1338999
    [PMID:28594268]
  17. Liu B,De Storme N,Geelen D
    Cold interferes with male meiotic cytokinesis in Arabidopsis thaliana independently of the AHK2/3-AHP2/3/5 cytokinin signaling module.
    Cell Biol. Int., 2017. 41(8): p. 879-889
    [PMID:28618065]
  18. Zhang F,May A,Irish VF
    Type-B ARABIDOPSIS RESPONSE REGULATORs Directly Activate WUSCHEL.
    Trends Plant Sci., 2017. 22(10): p. 815-817
    [PMID:28886911]
  19. Yan Z, et al.
    Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1.
    Plant Physiol., 2017. 175(3): p. 1438-1454
    [PMID:28931628]
  20. Rong XF, et al.
    Type-B ARRs Control Carpel Regeneration Through Mediating AGAMOUS Expression in Arabidopsis.
    Plant Cell Physiol., 2018. 59(4): p. 756-764
    [PMID:29186581]
  21. Bustillo-Avendaño E, et al.
    Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis.
    Plant Physiol., 2018. 176(2): p. 1709-1727
    [PMID:29233938]
  22. Waldie T,Leyser O
    Cytokinin Targets Auxin Transport to Promote Shoot Branching.
    Plant Physiol., 2018. 177(2): p. 803-818
    [PMID:29717021]