PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cotton_A_26203_BGI-A2_v1.0
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family MYB
Protein Properties Length: 317aa    MW: 34537.2 Da    PI: 4.9306
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cotton_A_26203_BGI-A2_v1.0genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding52.11.5e-161461148
                                TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
             Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                                +g+WT+eEd++l+ +++++G g W+  +++ g+ R++k+c++rw +yl
  Cotton_A_26203_BGI-A2_v1.0 14 KGAWTAEEDQKLISYIQKHGEGGWRFLPQKAGLQRCGKSCRLRWANYL 61
                                79********************************************97 PP

2Myb_DNA-binding52.41.2e-1667111147
                                 TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS
             Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 
                                 rg +++eEd+ ++++ ++lG++ W++Iar++  +Rt++++k++w+ +
  Cotton_A_26203_BGI-A2_v1.0  67 RGDFSPEEDKTIIKLQAELGNR-WAAIARHLS-NRTDNEIKNYWNAH 111
                                 899*******************.*********.***********976 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129416.333961IPR017930Myb domain
SuperFamilySSF466893.1E-3011108IPR009057Homeodomain-like
SMARTSM007177.1E-121363IPR001005SANT/Myb domain
PfamPF002493.0E-151461IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.8E-231568IPR009057Homeodomain-like
CDDcd001673.88E-101661No hitNo description
PROSITE profilePS5129425.05662116IPR017930Myb domain
SMARTSM007178.5E-1766114IPR001005SANT/Myb domain
PfamPF002493.1E-1567112IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.602.9E-2569116IPR009057Homeodomain-like
CDDcd001672.63E-1270112No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 317 aa     Download sequence    Send to blast
MGRTPFCSSD GLKKGAWTAE EDQKLISYIQ KHGEGGWRFL PQKAGLQRCG KSCRLRWANY  60
LRPGIKRGDF SPEEDKTIIK LQAELGNRWA AIARHLSNRT DNEIKNYWNA HLKKRLANMG  120
ADQVTVSGAS SSSGNSDSNA VTNTECAKPQ QSEPTKKRSA SALLLNKLAT RVTQCVGPLR  180
ASQTLQQPTM PFNGGAENSD IFCHPLPSST PESTSWADNN NISNSLTIPE CGTTNAIDER  240
DSSSSAGVLN AIVASEFASL TCVDELSDWG NTNYSIEPEQ VQIDYSDSMT VGYGGLWDDD  300
VIVVDDDDYT VGSLGFL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gv2_A2e-26121162105MYB PROTO-ONCOGENE PROTEIN
1mse_C2e-26121162105C-Myb DNA-Binding Domain
1msf_C2e-26121162105C-Myb DNA-Binding Domain
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in tryptophan gene activation and in indole-3-acetic acid (IAA) and indolic glucosinolates (IG) biosynthesis. Acts as a direct transcriptional activator of both Trp synthesis genes and Trp secondary metabolism genes. {ECO:0000269|PubMed:15579661, ECO:0000269|PubMed:23580754, ECO:0000269|PubMed:23943862, ECO:0000269|PubMed:9576939}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by herbivory. {ECO:0000269|PubMed:23943862}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017639917.10.0PREDICTED: transcription factor MYB34
SwissprotO643997e-65MYB34_ARATH; Transcription factor MYB34
TrEMBLA0A0D2MLR50.0A0A0D2MLR5_GOSRA; Uncharacterized protein
STRINGGorai.003G097900.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM4282646
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G60890.14e-66myb domain protein 34
Publications ? help Back to Top
  1. Grubb CD,Abel S
    Glucosinolate metabolism and its control.
    Trends Plant Sci., 2006. 11(2): p. 89-100
    [PMID:16406306]
  2. De Schutter K, et al.
    Arabidopsis WEE1 kinase controls cell cycle arrest in response to activation of the DNA integrity checkpoint.
    Plant Cell, 2007. 19(1): p. 211-25
    [PMID:17209125]
  3. Kim K,Jiang K,Teng SL,Feldman LJ,Huang H
    Using biologically interrelated experiments to identify pathway genes in Arabidopsis.
    Bioinformatics, 2012. 28(6): p. 815-22
    [PMID:22271267]
  4. Guo R, et al.
    Jasmonic acid and glucose synergistically modulate the accumulation of glucosinolates in Arabidopsis thaliana.
    J. Exp. Bot., 2013. 64(18): p. 5707-19
    [PMID:24151308]
  5. Benstein RM, et al.
    Arabidopsis phosphoglycerate dehydrogenase1 of the phosphoserine pathway is essential for development and required for ammonium assimilation and tryptophan biosynthesis.
    Plant Cell, 2013. 25(12): p. 5011-29
    [PMID:24368794]
  6. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  7. Frerigmann H,Gigolashvili T
    MYB34, MYB51, and MYB122 distinctly regulate indolic glucosinolate biosynthesis in Arabidopsis thaliana.
    Mol Plant, 2014. 7(5): p. 814-28
    [PMID:24431192]
  8. Frerigmann H,Gigolashvili T
    Update on the role of R2R3-MYBs in the regulation of glucosinolates upon sulfur deficiency.
    Front Plant Sci, 2014. 5: p. 626
    [PMID:25426131]
  9. Frerigmann H,Glawischnig E,Gigolashvili T
    The role of MYB34, MYB51 and MYB122 in the regulation of camalexin biosynthesis in Arabidopsis thaliana.
    Front Plant Sci, 2015. 6: p. 654
    [PMID:26379682]
  10. Frerigmann H, et al.
    Regulation of Pathogen-Triggered Tryptophan Metabolism in Arabidopsis thaliana by MYB Transcription Factors and Indole Glucosinolate Conversion Products.
    Mol Plant, 2016. 9(5): p. 682-695
    [PMID:26802248]
  11. Stahl E, et al.
    Regulatory and Functional Aspects of Indolic Metabolism in Plant Systemic Acquired Resistance.
    Mol Plant, 2016. 9(5): p. 662-681
    [PMID:26802249]
  12. Bulgakov VP,Veremeichik GN,Grigorchuk VP,Rybin VG,Shkryl YN
    The rolB gene activates secondary metabolism in Arabidopsis calli via selective activation of genes encoding MYB and bHLH transcription factors.
    Plant Physiol. Biochem., 2016. 102: p. 70-9
    [PMID:26913794]
  13. Miao H, et al.
    Glucose enhances indolic glucosinolate biosynthesis without reducing primary sulfur assimilation.
    Sci Rep, 2016. 6: p. 31854
    [PMID:27549907]