PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Home  TFext  BLAST  Prediction  Download  Help  About  Links  PlantRegMap
(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cotton_A_16760_BGI-A2_v1.0
Organism
Gossypium arboreum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family ARF
Protein Properties Length: 737aa    MW: 81824.1 Da    PI: 6.4668
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cotton_A_16760_BGI-A2_v1.0genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B371.51.1e-22127228199
                                 EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--T CS
                          B3   1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLke 76 
                                 f k+lt sd++++g +++p++ ae+        +++++  ++l+ +d++  +W++++i+r++++r++lt+GW+ Fv+a++L +
  Cotton_A_16760_BGI-A2_v1.0 127 FYKTLTASDTSTHGGFSVPRRAAEKVfppldfsQQPPA--QELIARDLHDIEWKFRHIFRGQPKRHLLTTGWSVFVSAKRLVA 207
                                 789****************************8544444..48***************************************** PP

                                 T-EEEEEE-SSSEE..EEEEE-S CS
                          B3  77 gDfvvFkldgrsefelvvkvfrk 99 
                                 gD+v+F   ++++ +l+++++r+
  Cotton_A_16760_BGI-A2_v1.0 208 GDSVLFI--WNEKNQLLLGIRRA 228
                                 *******..8899999****997 PP
2Auxin_resp117.79.6e-39253336183
                  Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsL 82 
                                 aahaa+t+s F+v+YnPras+s+F+++++k++ka+  ++vsvGmRf+m fete+ss rr++Gt++g+s ldpvrWpnS+Wrs+
  Cotton_A_16760_BGI-A2_v1.0 253 AAHAAATNSCFTVFYNPRASPSDFIIPLSKYVKAVFhTRVSVGMRFRMLFETEESSVRRYMGTITGISSLDPVRWPNSHWRSV 335
                                 79********************************87599******************************************98 PP

                  Auxin_resp  83 k 83 
                                 k
  Cotton_A_16760_BGI-A2_v1.0 336 K 336
                                 5 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019362.22E-48112256IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.101.6E-40120242IPR015300DNA-binding pseudobarrel domain
CDDcd100178.47E-21126227No hitNo description
SMARTSM010196.4E-22127229IPR003340B3 DNA binding domain
PROSITE profilePS5086312.421127229IPR003340B3 DNA binding domain
PfamPF023625.3E-21127228IPR003340B3 DNA binding domain
PfamPF065078.5E-34253336IPR010525Auxin response factor
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 737 aa     Download sequence    Send to blast
MKLSASGQGQ QAHEGENKCL NLELWHACAG PLVCLPTVGT RVVYFPQGHS EQVAATTNKE  60
VDTHIPNYPD LPPQLICQLQ NVTMHADVET DEVYAQMSLQ PLTPEEQKGA FLPMELGIPS  120
KQPTNYFYKT LTASDTSTHG GFSVPRRAAE KVFPPLDFSQ QPPAQELIAR DLHDIEWKFR  180
HIFRGQPKRH LLTTGWSVFV SAKRLVAGDS VLFIWNEKNQ LLLGIRRATR PQTVMPSSVL  240
SSDSMHIGLL AAAAHAAATN SCFTVFYNPR ASPSDFIIPL SKYVKAVFHT RVSVGMRFRM  300
LFETEESSVR RYMGTITGIS SLDPVRWPNS HWRSVKVGWD ESTTGERQPR VSLWEIEPLT  360
TFPMYPSLFP LRLKRPWHPG SSSLFDNRDD ISNGLTWLRG GSGEQGLQSL NLQSFCSYPW  420
MQQKLDLSFP GNDYNLQYQH MLANGLQNLG SGDPPRQQLQ QSFQYVQQPG SHNLLLQQQQ  480
QQQQQQQSVS QLVPHNIVQA QQSIIRIESF LPVPGREQVG NQSEEQAQQQ HNMTQSDQLQ  540
QRRQLNVPSS FLKPDFIDSG SGPPVLDMLG SLCPESSANL LNFSTTGQSM LADQLPQLSW  600
APKYAHLNVN TFAGSTSVPQ VSPGKDATVE LDIGTSDAQN STFFGVNDDS FGLLLPTSMR  660
GFTTSSSEAD MPSIPLGDPS FQNPLYGCMQ YSSELQSTGQ VDPPTSSRTF IKLPFGDLIP  720
VLAAANREAR GSPLANL
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A1e-1572035751388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017620042.10.0PREDICTED: auxin response factor 8-like isoform X1
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A1U8NZF40.0A0A1U8NZF4_GOSHI; Auxin response factor
STRINGGorai.001G204500.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM13442894
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.20.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]