PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cotton_A_16132_BGI-A2_v1.0
Common NameF383_06866
Organism
Gossypium arboreum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family C2H2
Protein Properties Length: 439aa    MW: 50893 Da    PI: 7.1689
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cotton_A_16132_BGI-A2_v1.0genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H211.90.00067197219123
                                 EEETTTTEEESSHHHHHHHHHHT CS
                     zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                                 y C+ C    +rk++L+rH+r++
  Cotton_A_16132_BGI-A2_v1.0 197 YFCEFCLNFMKRKEQLQRHMRKC 219
                                 78*******************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541601.37E-2247164IPR016197Chromo domain-like
Gene3DG3DSA:2.30.30.2703.3E-3752123No hitNo description
PfamPF117174.6E-2153111IPR025995RNA binding activity-knot of a chromodomain
CDDcd000242.83E-666112No hitNo description
SMARTSM002984.0E-667126IPR000953Chromo/chromo shadow domain
Gene3DG3DSA:2.30.30.2703.3E-37158208No hitNo description
PROSITE profilePS5172675.469163434IPR002717Histone acetyltransferase domain, MYST-type
SuperFamilySSF557292.24E-111164435IPR016181Acyl-CoA N-acyltransferase
Gene3DG3DSA:3.40.630.304.2E-73222365IPR016181Acyl-CoA N-acyltransferase
PfamPF018533.0E-84224401IPR002717Histone acetyltransferase domain, MYST-type
CDDcd043010.00191275333No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006281Biological ProcessDNA repair
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010224Biological Processresponse to UV-B
GO:0016573Biological Processhistone acetylation
GO:2000028Biological Processregulation of photoperiodism, flowering
GO:0005634Cellular Componentnucleus
GO:0043995Molecular Functionhistone acetyltransferase activity (H4-K5 specific)
Sequence ? help Back to Top
Protein Sequence    Length: 439 aa     Download sequence    Send to blast
MGSIDTPTIT ENGSTQSYAA AAPADDNQRP LASSNGAQES EATKKRRSGI LPLEVGTRVM  60
CRWRDGKYHP VKVIERRKLQ SAEPSDYEYY VHYTEFNRRL DEWVKLEQLD LDSVETVVDE  120
KVEDKVASLK MTRHQKRKID ETHVEVGHEE LDAASLREHE EFTKVKNIAT IELGRYEIET  180
WYFSPFPPEY NDSLKLYFCE FCLNFMKRKE QLQRHMRKCD LKHPPGDEIY RSGTLSMFEV  240
DGKKNKVYGQ NLCYLAKLFL DHKTLYYDVD LFLFYVLCEC DDRGCHMVGY FSKEKHSEES  300
YNLACILTLP PYQRKGYGKF LIAFSYELSK KEGKVGTPER PLSDLGLLSY RGYWTRVLLD  360
ILKKHKGNIS IKELSDMTAI KAEDILTTLQ SLELIQYRKG QHVICADPKV LDRHLKAAGR  420
GGLEVDVSKL IWTPYKEQS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4dnc_A1e-1191594381282Histone acetyltransferase KAT8
4dnc_B1e-1191594381282Histone acetyltransferase KAT8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtHistone acetyltransferase which may be involved in transcriptional activation. Acetylates 'Lys-5' of histone H4 (H4K5ac) (PubMed:17877703, PubMed:19040736, PubMed:22170978, PubMed:23273925). Essential for gametophyte development (PubMed:19040736). Involved in DNA repair after UV-B exposure (PubMed:22170978). Negative regulator of flowering controlling the H4K5ac levels in the FLC chromatin (PubMed:23273925). {ECO:0000269|PubMed:17877703, ECO:0000269|PubMed:19040736, ECO:0000269|PubMed:22170978, ECO:0000269|PubMed:23273925}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated upon UV-B exposure. {ECO:0000269|PubMed:22170978}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_017650033.10.0PREDICTED: histone acetyltransferase of the MYST family 1
SwissprotQ9FLF70.0MYST1_ARATH; Histone acetyltransferase of the MYST family 1
TrEMBLA0A0B0NHE10.0A0A0B0NHE1_GOSAR; Histone acetyltransferase
TrEMBLA0A2P5YT970.0A0A2P5YT97_GOSBA; Histone acetyltransferase
STRINGGorai.009G242400.10.0(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM480656
Publications ? help Back to Top
  1. Latrasse D, et al.
    The MYST histone acetyltransferases are essential for gametophyte development in Arabidopsis.
    BMC Plant Biol., 2008. 8: p. 121
    [PMID:19040736]
  2. Campi M,D'Andrea L,Emiliani J,Casati P
    Participation of chromatin-remodeling proteins in the repair of ultraviolet-B-damaged DNA.
    Plant Physiol., 2012. 158(2): p. 981-95
    [PMID:22170978]
  3. Bari A,Orazova S,Ivashchenko A
    miR156- and miR171-binding sites in the protein-coding sequences of several plant genes.
    Biomed Res Int, 2013. 2013: p. 307145
    [PMID:23936788]
  4. Xu Y, et al.
    Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes.
    Nucleic Acids Res., 2014. 42(17): p. 10960-74
    [PMID:25183522]
  5. Raevsky AV,Sharifi M,Samofalova DA,Karpov PA,Blume YB
    3D structure prediction of histone acetyltransferase proteins of the MYST family and their interactome in Arabidopsis thaliana.
    J Mol Model, 2016. 22(11): p. 256
    [PMID:27709438]
  6. Fina JP,Masotti F,Rius SP,Crevacuore F,Casati P
    HAC1 and HAF1 Histone Acetyltransferases Have Different Roles in UV-B Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1179
    [PMID:28740501]