PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Cotton_A_15048_BGI-A2_v1.0
Common NameF383_22743
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
Family LSD
Protein Properties Length: 173aa    MW: 18258.3 Da    PI: 8.1291
Description LSD family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Cotton_A_15048_BGI-A2_v1.0genomeBGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-LSD1406.3e-131135125
                     zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                                C+ Cr++L YPrGA++V+CalC+t+
  Cotton_A_15048_BGI-A2_v1.0 11 CSRCRNILLYPRGATNVCCALCNTI 35
                                9**********************97 PP

2zf-LSD142.88.4e-145074125
                     zf-LSD1  1 CggCrtlLsYPrGApsVRCalCdtV 25
                                CggCrtlL+Y+ GA+sVRC++C+ +
  Cotton_A_15048_BGI-A2_v1.0 50 CGGCRTLLMYTCGATSVRCSCCNII 74
                                **********************976 PP

3zf-LSD144.72.2e-1488112125
                     zf-LSD1   1 CggCrtlLsYPrGApsVRCalCdtV 25 
                                 Cg+Crt+L+YP+GA sV+Ca+C+ V
  Cotton_A_15048_BGI-A2_v1.0  88 CGHCRTTLMYPYGAASVKCAVCHYV 112
                                 **********************987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
TIGRFAMsTIGR010533.5E-12938IPR005735Zinc finger, LSD1-type
PfamPF069433.8E-111135IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010531.7E-144777IPR005735Zinc finger, LSD1-type
PfamPF069433.2E-115073IPR005735Zinc finger, LSD1-type
TIGRFAMsTIGR010531.3E-1285115IPR005735Zinc finger, LSD1-type
PfamPF069432.4E-1388112IPR005735Zinc finger, LSD1-type
Sequence ? help Back to Top
Protein Sequence    Length: 173 aa     Download sequence    Send to blast
MIADMQSEVV CSRCRNILLY PRGATNVCCA LCNTITQVPP PGMEMAQLVC GGCRTLLMYT  60
CGATSVRCSC CNIINHVTAS NPMAHINCGH CRTTLMYPYG AASVKCAVCH YVTNVGVSTG  120
NVRCPLPASS LNARGTMPST STSQTVVVEN PMSVDESGKL VSNVVVGITT DKK
Functional Description ? help Back to Top
Source Description
UniProtNegative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269|PubMed:10550898, ECO:0000269|PubMed:11595797, ECO:0000269|PubMed:11844114, ECO:0000269|PubMed:12732715, ECO:0000269|PubMed:15347794, ECO:0000269|PubMed:16957775, ECO:0000269|PubMed:18055613, ECO:0000269|PubMed:18790826, ECO:0000269|PubMed:20456049, ECO:0000269|PubMed:21097903}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By methyl viologen. {ECO:0000269|PubMed:20456049}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_016730172.11e-116PREDICTED: protein LSD1-like
RefseqXP_016730173.11e-116PREDICTED: protein LSD1-like
RefseqXP_017603108.11e-116PREDICTED: protein LSD1-like isoform X1
RefseqXP_017603109.11e-116PREDICTED: protein LSD1-like isoform X1
SwissprotP940771e-65LSD1_ARATH; Protein LSD1
TrEMBLA0A0B0NU081e-114A0A0B0NU08_GOSAR; Protein LOL3
TrEMBLA0A1U8MXC51e-114A0A1U8MXC5_GOSHI; protein LSD1-like
TrEMBLA0A2P5VX731e-114A0A2P5VX73_GOSBA; Uncharacterized protein
STRINGGorai.009G116000.11e-115(Gossypium raimondii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM53452650
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G20380.75e-68LSD family protein
Publications ? help Back to Top
  1. Spedaletti V, et al.
    Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana.
    Biochemistry, 2008. 47(17): p. 4936-47
    [PMID:18393445]
  2. Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S
    PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties.
    Plant Cell Rep., 2016. 35(3): p. 527-39
    [PMID:26754794]
  3. Czarnocka W, et al.
    The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator.
    Plant Cell Environ., 2017. 40(11): p. 2644-2662
    [PMID:28555890]
  4. Bernacki MJ, et al.
    LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana.
    Physiol Plant, 2019. 165(2): p. 369-382
    [PMID:30461017]