PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Cotton_A_02627_BGI-A2_v1.0

Organism

Gossypium arboreum

Taxonomic ID

29729

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium

Family

E2F/DP

Protein Properties

Length: 271aa MW: 30233.2 Da PI: 4.3193

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Cotton_A_02627_BGI-A2_v1.0	genome	BGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	47.7	2.5e-15	31	61	38	70
E2F_TDP 38 dvknkrRRiYDilNVLealnliekkekneirwk 70 +v ++RRiYDi+NVLe+++liekk kn+i+wk Cotton_A_02627_BGI-A2_v1.0 31 EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWK 61 34..9***************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM01372	1.9E-5	2	62	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	1.22E-9	28	61	IPR011991	Winged helix-turn-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	1.0E-13	30	61	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	3.0E-13	31	61	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF144074	3.14E-14	51	118	No hit	No description
Pfam	PF16421	2.6E-15	53	116	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 271 aa Download sequence Send to blast
MRENIVVSTT SSNHGDKYYT LLGGLAPCVI EVQKRRIYDI TNVLEGIGLI EKKLKNRIQW 60 KWLFVTEEDI KSLPCFQNEM LIAIKAPHGT ILEVPDPDED DDSLQRRYRI VLGSSNFQWT 120 FLIIPLISLC YSIEIEEKFE EIQGVGLPSN LPSTSGLDEN PAASMVTLES REVETQGRYI 180 NGMCLDHHVS QDFVSGIMKI VPSDLDNDAD YRLLSDPSVS ITDIWRTESG IELSNFDILQ 240 YTGMAAGSTT QPQTPPLNAA EVPPPGNSTG R

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_012462323.1	1e-131	PREDICTED: transcription factor E2FB-like isoform X6
Swissprot	Q9FV71	2e-49	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A0D2VKC2	1e-133	A0A0D2VKC2_GOSRA; Uncharacterized protein
STRING	Gorai.013G257100.1	1e-125	(Gossypium raimondii)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.2	7e-52	E2F transcription factor 1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]