PlantRegMap/PlantTFDB v5.0
Plant Transcription
Factor Database
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Transcription Factor Information
Basic Information? help Back to Top | |||||||||
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TF ID | Cotton_A_02626_BGI-A2_v1.0 | ||||||||
Organism | |||||||||
Taxonomic ID | |||||||||
Taxonomic Lineage |
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium
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Family | E2F/DP | ||||||||
Protein Properties | Length: 306aa MW: 34059.9 Da PI: 4.3049 | ||||||||
Description | E2F/DP family protein | ||||||||
Gene Model |
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Signature Domain? help Back to Top | |||||||
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No. | Domain | Score | E-value | Start | End | HMM Start | HMM End |
1 | E2F_TDP | 60.3 | 2.9e-19 | 16 | 61 | 21 | 71 |
E2F_TDP 21 eegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 e+g ++ln++a +L +v ++RRiYDi+NVLe+++liekk kn+i+wkg Cotton_A_02626_BGI-A2_v1.0 16 EDGSLDLNKAAGTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 61 6799**********...99..****************************98 PP |
Protein Features ? help Back to Top | ||||||
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Database | Entry ID | E-value | Start | End | InterPro ID | Description |
SMART | SM01372 | 4.0E-16 | 1 | 61 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
SuperFamily | SSF46785 | 7.21E-13 | 14 | 62 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
Pfam | PF02319 | 2.7E-17 | 15 | 61 | IPR003316 | E2F/DP family, winged-helix DNA-binding domain |
Gene3D | G3DSA:1.10.10.10 | 2.5E-19 | 15 | 63 | IPR011991 | Winged helix-turn-helix DNA-binding domain |
CDD | cd14660 | 2.42E-39 | 72 | 178 | No hit | No description |
SuperFamily | SSF144074 | 5.23E-33 | 73 | 177 | No hit | No description |
Pfam | PF16421 | 9.4E-34 | 77 | 176 | IPR032198 | E2F transcription factor, CC-MB domain |
Gene Ontology ? help Back to Top | ||||||
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GO Term | GO Category | GO Description | ||||
GO:0006355 | Biological Process | regulation of transcription, DNA-templated | ||||
GO:0005667 | Cellular Component | transcription factor complex | ||||
GO:0003700 | Molecular Function | transcription factor activity, sequence-specific DNA binding |
Sequence ? help Back to Top |
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Protein Sequence Length: 306 aa Download sequence Send to blast |
KSSKFGPQTP SSALAEDGSL DLNKAAGTLE VQKRRIYDIT NVLEGIGLIE KKLKNRIQWK 60 GLDVSRPGEV DENVATLQAE VENLHNQEHR LDGQIRKMQE RLRDLSEDEN NSKWLFVTEE 120 DIKSLPCFQN EMLIAIKAPH GTTLEVPDPD EDDDSLQRRY RLVLRSSMGP IDVYLVSQIE 180 EKFEEVQGVG LPSNLPSTSG LDENPAEVET QGQYINGMCL DHHVSQDFVS GIMKFVPSNL 240 DNDADYWLLS DPSVSITNIW RTESGIELNN FDILQYTGMA AGSTTQPQTP PLNAAEVPPP 300 GNSTGR |
3D Structure ? help Back to Top | ||||||
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PDB ID | Evalue | Query Start | Query End | Hit Start | Hit End | Description |
5tuu_B | 8e-18 | 69 | 178 | 5 | 110 | Transcription factor E2F4 |
Search in ModeBase |
Functional Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}. |
Regulation -- Description ? help Back to Top | ||||||
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Source | Description | |||||
UniProt | INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}. |
Annotation -- Protein ? help Back to Top | |||||||
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Source | Hit ID | E-value | Description | ||||
Refseq | XP_016729709.1 | 0.0 | PREDICTED: transcription factor E2FB-like | ||||
Swissprot | Q9FV71 | 1e-104 | E2FB_ARATH; Transcription factor E2FB | ||||
TrEMBL | A0A1U8MVV2 | 0.0 | A0A1U8MVV2_GOSHI; transcription factor E2FB-like | ||||
STRING | Gorai.013G257100.1 | 0.0 | (Gossypium raimondii) |
Orthologous Group ? help Back to Top | |||
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Lineage | Orthologous Group ID | Taxa Number | Gene Number |
Malvids | OGEM808 | 28 | 121 |
Best hit in Arabidopsis thaliana ? help Back to Top | ||||||
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Hit ID | E-value | Description | ||||
AT5G22220.2 | 1e-106 | E2F transcription factor 1 |
Publications ? help Back to Top | |||
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