PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

mrna19478.1-v1.0-hybrid

Organism

Fragaria vesca

Taxonomic ID

57918

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae; Fragaria

Family

WRKY

Protein Properties

Length: 647aa MW: 70202 Da PI: 8.6397

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
mrna19478.1-v1.0-hybrid	genome	GDR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	96.6	1.6e-30	385	443	2	59
--SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS WRKY 2 dDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 Dg++WrKYGqK+ kg+++pr+YYrCt+a gCpv+k+v+r+a+d +++++tYeg+Hnh+ mrna19478.1-v1.0-hybrid 385 TDGCQWRKYGQKMAKGNPCPRAYYRCTMAvGCPVRKQVQRCADDRTILITTYEGNHNHP 443 7*********************************************************7 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	3.1E-33	369	445	IPR003657	WRKY domain
SuperFamily	SSF118290	1.26E-27	377	445	IPR003657	WRKY domain
PROSITE profile	PS50811	29.516	379	445	IPR003657	WRKY domain
SMART	SM00774	1.0E-36	384	444	IPR003657	WRKY domain
Pfam	PF03106	2.0E-26	386	443	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 647 aa Download sequence Send to blast
MRESRVEKVS YTRLVSNLVV IKRKRNNQVT IAVSQVDNWV GWQGNPDAPS DVRICPREKV 60 LSTSRVYVPI VQFDFMDKGW GLTLESDSLG FFLNKPPPGA AAPPPLNKRT NLFGDRMFSG 120 IEFPVKTRPA DENRTAEVDF FSDKKNKSDD DHGLKSNNTS VSVKKENWSG LDAVNTGLHL 180 VTANAGSDQS TVDDGVSSDP ADSKRAKNHE LALLQVELQR MNAENQRLKE MLGQVTNNYT 240 ALQTHLVAVM HQQQQNQAAA DQTSQDRDQN EEKSEEKRHE IGSSGATVPR QFLNLGPREE 300 TKTENEVSNS SSEARTRSDS PQNNVSANGK RVGREESPES ETQGWVPNKV AKPDSPPKPI 360 DQATEATMRK ARVSVRARSE APMITDGCQW RKYGQKMAKG NPCPRAYYRC TMAVGCPVRK 420 QVQRCADDRT ILITTYEGNH NHPLPPAAMA MASTTTAAAS MLLSGSMSSA DGIMNPNNLL 480 ARAILPCSSS VATISASAPF PTVTLDLTTS PPLQFQRPQQ GQFQMPFPGQ PQNFGSSGSS 540 PQLPQAFGQA LYNQSKFSGL QLSQELLAHQ AQQQQQQSQT SSFADTVSAA TAAITADPTF 600 TAALAAAITS IIGGSSHPNN NNNNSTTSNN SNGANNNNKI NSFPGK*

Sequence ? help Back to Top

Protein Sequence Length: 647 aa Download sequence Send to blast

MRESRVEKVS YTRLVSNLVV IKRKRNNQVT IAVSQVDNWV GWQGNPDAPS DVRICPREKV  60
LSTSRVYVPI VQFDFMDKGW GLTLESDSLG FFLNKPPPGA AAPPPLNKRT NLFGDRMFSG  120
IEFPVKTRPA DENRTAEVDF FSDKKNKSDD DHGLKSNNTS VSVKKENWSG LDAVNTGLHL  180
VTANAGSDQS TVDDGVSSDP ADSKRAKNHE LALLQVELQR MNAENQRLKE MLGQVTNNYT  240
ALQTHLVAVM HQQQQNQAAA DQTSQDRDQN EEKSEEKRHE IGSSGATVPR QFLNLGPREE  300
TKTENEVSNS SSEARTRSDS PQNNVSANGK RVGREESPES ETQGWVPNKV AKPDSPPKPI  360
DQATEATMRK ARVSVRARSE APMITDGCQW RKYGQKMAKG NPCPRAYYRC TMAVGCPVRK  420
QVQRCADDRT ILITTYEGNH NHPLPPAAMA MASTTTAAAS MLLSGSMSSA DGIMNPNNLL  480
ARAILPCSSS VATISASAPF PTVTLDLTTS PPLQFQRPQQ GQFQMPFPGQ PQNFGSSGSS  540
PQLPQAFGQA LYNQSKFSGL QLSQELLAHQ AQQQQQQSQT SSFADTVSAA TAAITADPTF  600
TAALAAAITS IIGGSSHPNN NNNNSTTSNN SNGANNNNKI NSFPGK*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2ayd_A	6e-22	371	447	1	76	WRKY transcription factor 1
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor involved in the control of processes related to senescence and pathogen defense (PubMed:12000796). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:12000796). Activates the transcription of the SIRK gene and represses its own expression and that of the WRKY42 genes (PubMed:12000796). Modulates phosphate homeostasis and Pi translocation by regulating PHO1 expression (PubMed:25733771). {ECO:0000269\|PubMed:12000796, ECO:0000269\|PubMed:25733771}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	mrna19478.1-v1.0-hybrid

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid, ethylene, jasmonic acid, pathogens, wounding and strongly during leaf senescence. {ECO:0000269\|PubMed:11449049, ECO:0000269\|PubMed:11722756}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_004293312.1	0.0	PREDICTED: probable WRKY transcription factor 31
Swissprot	Q9C519	1e-157	WRKY6_ARATH; WRKY transcription factor 6
TrEMBL	A0A2P6Q2I4	0.0	A0A2P6Q2I4_ROSCH; Putative transcription factor WRKY family
STRING	XP_004293312.1	0.0	(Fragaria vesca)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF866	34	121

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G62300.1	1e-121	WRKY family protein

Link Out ? help Back to Top
Phytozome	mrna19478.1-v1.0-hybrid

Publications ? help Back to Top
Zhou F, et al. High humidity suppresses ssi4-mediated cell death and disease resistance upstream of MAP kinase activation, H2O2 production and defense gene expression. Plant J., 2004. 39(6): p. 920-32 [PMID:15341634] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P An extracellular subtilase switch for immune priming in Arabidopsis. PLoS Pathog., 2013. 9(6): p. e1003445 [PMID:23818851] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Singh V,Roy S,Singh D,Nandi AK Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes. J. Biosci., 2014. 39(1): p. 119-26 [PMID:24499796] Ali MA,Wieczorek K,Kreil DP,Bohlmann H The beet cyst nematode Heterodera schachtii modulates the expression of WRKY transcription factors in syncytia to favour its development in Arabidopsis roots. PLoS ONE, 2014. 9(7): p. e102360 [PMID:25033038] Chai J,Liu J,Zhou J,Xing D Mitogen-activated protein kinase 6 regulates NPR1 gene expression and activation during leaf senescence induced by salicylic acid. J. Exp. Bot., 2014. 65(22): p. 6513-28 [PMID:25210078] Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress. Plant Cell, 2014. 26(12): p. 4656-79 [PMID:25549671] Xiao D, et al. SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis. Plant Physiol., 2015. 169(2): p. 1275-91 [PMID:26304848] Bakshi M, et al. WRKY6 restricts Piriformospora indica-stimulated and phosphate-induced root development in Arabidopsis. BMC Plant Biol., 2015. 15: p. 305 [PMID:26718529] Huang Y,Feng CZ,Ye Q,Wu WH,Chen YF Arabidopsis WRKY6 Transcription Factor Acts as a Positive Regulator of Abscisic Acid Signaling during Seed Germination and Early Seedling Development. PLoS Genet., 2016. 12(2): p. e1005833 [PMID:26829043] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P Correction: An Extracellular Subtilase Switch for Immune Priming in Arabidopsis. PLoS Pathog., 2016. 12(11): p. e1006003 [PMID:27806116] Li H, et al. BZR1 Positively Regulates Freezing Tolerance via CBF-Dependent and CBF-Independent Pathways in Arabidopsis. Mol Plant, 2017. 10(4): p. 545-559 [PMID:28089951] Stetter MG,Benz M,Ludewig U Increased root hair density by loss of WRKY6 in Arabidopsis thaliana. PeerJ, 2017. 5: p. e2891 [PMID:28149680] Zhou X, et al. StMYB44 negatively regulates phosphate transport by suppressing expression of PHOSPHATE1 in potato. J. Exp. Bot., 2017. 68(5): p. 1265-1281 [PMID:28338870] Bakshi M, et al. Piriformospora indica Reprograms Gene Expression in Arabidopsis Phosphate Metabolism Mutants But Does Not Compensate for Phosphate Limitation. Front Microbiol, 2017. 8: p. 1262 [PMID:28747898] Zhang Y, et al. DELLA proteins negatively regulate dark-induced senescence and chlorophyll degradation in Arabidopsis through interaction with the transcription factor WRKY6. Plant Cell Rep., 2018. 37(7): p. 981-992 [PMID:29574486]