PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID mrna09494.1-v1.0-hybrid
Organism
Fragaria vesca
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae; Fragaria
Family E2F/DP
Protein Properties Length: 415aa    MW: 45848.2 Da    PI: 9.0345
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
mrna09494.1-v1.0-hybridgenomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP65.57.3e-2127118171
                  E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.........................dvknkrRRiYDilNVLealnliek 61 
                              rk+ksL+ll+++f++l+ ++  + v l+++a++L                             v  +rRRiYDi+NVLe+++++++
  mrna09494.1-v1.0-hybrid  27 RKQKSLGLLCSNFISLYDREGVTSVGLDDAASKL--GlisfcnieilrrsifgdlmsvgkcaGV--ERRRIYDIVNVLESVGVLAR 108
                              79*****************999************..44689*******************9888..******************** PP

                  E2F_TDP  62 kekneirwkg 71 
                              k+kn+++wkg
  mrna09494.1-v1.0-hybrid 109 KAKNQYSWKG 118
                              ********98 PP
2E2F_TDP741.5e-23191272171
                  E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.......dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                              r+eksL lltq+f+kl+ +s+ + ++l+e+ak L+ +           k+RRiYDi+NVL+++nliek     ++k++++w g
  mrna09494.1-v1.0-hybrid 191 RREKSLALLTQNFVKLFVCSTVESISLDEAAKLLLGDvhnasimR-TAKVRRIYDIANVLSSMNLIEKthtadTRKPAYKWLG 272
                              689***************************************752.2589***********************9*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.6E-2323119IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013724.2E-2127118IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023197.1E-1828118IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467858.98E-1229119IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.7E-23187273IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.8E-30191272IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023196.0E-19193272IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467858.52E-13193273IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 415 aa     Download sequence    Send to blast
MDPAAPPPPP PPTQPETTST RHHSYSRKQK SLGLLCSNFI SLYDREGVTS VGLDDAASKL  60
GLISFCNIEI LRRSIFGDLM SVGKCAGVER RRIYDIVNVL ESVGVLARKA KNQYSWKGFG  120
AIPDTLQELK EAGLKENFNT FHGNFQGSDD PKCSQGSDDE EGDESGPATG SQNENPGANP  180
KSSANSKNDN RREKSLALLT QNFVKLFVCS TVESISLDEA AKLLLGDVHN ASIMRTAKVR  240
RIYDIANVLS SMNLIEKTHT ADTRKPAYKW LGLRGKDAAS SASDESRKRA FGTDITNVSS  300
KRGKGESSTT GKLEAQIQKQ HESTVRQRES IVRTVDKNNS EDSREGTKSY QFGPFAPVTI  360
ARAGNFNMKK VDWDNFSSTY RPQYQNQAVK ELFSHYMEAW KSWYSEVVEK PIQA*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A4e-32262643228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapmrna09494.1-v1.0-hybrid
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011464533.10.0PREDICTED: E2F transcription factor-like E2FE isoform X1
SwissprotQ8LSZ41e-129E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A2P6P2730.0A0A2P6P273_ROSCH; Putative transcription factor E2F-DP family
STRINGXP_004301283.10.0(Fragaria vesca)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-132DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]