PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID mrna08432.1-v1.0-hybrid
Organism
Fragaria vesca
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae; Fragaria
Family E2F/DP
Protein Properties Length: 516aa    MW: 57239.4 Da    PI: 4.7732
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
mrna08432.1-v1.0-hybridgenomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP80.71.3e-25168228671
                  E2F_TDP   6 LrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 
                              L+llt+kf++l++++e+gi++ln++a++L   +v  ++RRiYDi+NVLe+++liekk kn+i+wkg
  mrna08432.1-v1.0-hybrid 168 LGLLTKKFINLIKHAEDGILDLNKAADTL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 228
                              99***************************...99..****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM013729.1E-29166228IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.09E-15167226IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.7E-26167230IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023196.9E-23168228IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF1440747.06E-33240345No hitNo description
CDDcd146602.47E-45242345No hitNo description
PfamPF164211.0E-31244343IPR032198E2F transcription factor, CC-MB domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008284Biological Processpositive regulation of cell proliferation
GO:0009733Biological Processresponse to auxin
GO:0010090Biological Processtrichome morphogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051302Biological Processregulation of cell division
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 516 aa     Download sequence    Send to blast
MSGYPPPPPF TSVKPPFSAS LDYHTFAPDV RQQPPEGITV KPSVSPLSHF NRSASRYSRV  60
KLELVHALKR KSDAVVYDEP TDRTAASEHI EFVNSPLQTP APVKVGKATK ASRASKLNKS  120
GPQTPASNVG SPSGGNLTPA GPCRYDSSLE NSERACASVK GMACLSHLGL LTKKFINLIK  180
HAEDGILDLN KAADTLEVQK RRIYDITNVL EGIGLIEKKL KNRIQWKGLE ATRTGDSDEN  240
YDGLKAQVEN LSTEEGRLDE QIREMQEKLS NLSEEESNKK WLFVTEEDIK GLPCFQNETL  300
IAIKAPHGTT LEVPDPDEAV DYPQRRYRMV LRSMMGPIDV YLVSQFEEKF EEINAAEEPR  360
NIPSTSGLNE NPAPIMVTEE RGKAVEIQGQ EDYRVSADPT APQDFMSGIM KIVPSDVNSD  420
ADYWLLSDDA TVSITDIWRT ETGVEWDEFG ALTEDYTMGN VTPRAQTLPS SATEMRRLVS  480
RKPVVYNYPI TTRLDEKVLR DDEILPEDPC AVIGR*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A3e-231682291274PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapmrna08432.1-v1.0-hybrid
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269|PubMed:16055635, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:18424613}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004291680.10.0PREDICTED: transcription factor E2FB
SwissprotQ9FV711e-138E2FB_ARATH; Transcription factor E2FB
TrEMBLA0A2P6QEC70.0A0A2P6QEC7_ROSCH; Putative transcription factor E2F-DP family
STRINGXP_004291680.10.0(Fragaria vesca)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF19473490
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G22220.21e-122E2F transcription factor 1
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Wu M,Liu L,Hijazi H,Chan C
    A multi-layer inference approach to reconstruct condition-specific genes and their regulation.
    Bioinformatics, 2013. 29(12): p. 1541-52
    [PMID:23610368]
  3. Kobayashi K, et al.
    Transcriptional repression by MYB3R proteins regulates plant organ growth.
    EMBO J., 2015. 34(15): p. 1992-2007
    [PMID:26069325]