PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID mrna06093.1-v1.0-hybrid
Organism
Fragaria vesca
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae; Fragaria
Family bHLH
Protein Properties Length: 370aa    MW: 41405.9 Da    PI: 8.4883
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
mrna06093.1-v1.0-hybridgenomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH33.38.6e-11168216354
                              HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
                      HLH   3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                              ++h ++Er+RR+++N+ +  Lr+l P     + k+ + a+i   ++e+Ik+L
  mrna06093.1-v1.0-hybrid 168 MSHIAVERNRRKQMNEHLKVLRTLTPCF---YIKRGDQASIIGGVIEFIKEL 216
                              68*************************9...9******************99 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.90.190.101.9E-4524164IPR029021Protein-tyrosine phosphatase-like
SMARTSM001953.4E-4230165IPR020422Dual specificity protein phosphatase domain
PROSITE profilePS5005432.18630167IPR020422Dual specificity protein phosphatase domain
CDDcd001274.51E-5731163No hitNo description
SuperFamilySSF527993.4E-3831164IPR029021Protein-tyrosine phosphatase-like
PfamPF007821.6E-2938164IPR000340Dual specificity phosphatase, catalytic domain
PROSITE profilePS5005613.3490147IPR000387Tyrosine specific protein phosphatases domain
PROSITE profilePS5088814.437165216IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.18E-14167232IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000831.56E-10168221No hitNo description
PfamPF000105.8E-8168216IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.103.2E-11169229IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003536.4E-10171222IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006470Biological Processprotein dephosphorylation
GO:0009913Biological Processepidermal cell differentiation
GO:0010374Biological Processstomatal complex development
GO:0005634Cellular Componentnucleus
GO:0008138Molecular Functionprotein tyrosine/serine/threonine phosphatase activity
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 370 aa     Download sequence    Send to blast
MDPIDDSLRK QLSALLRVIH VTRCCKEDKV PCQIEEGLFL GSIGSAHNKD ELKELNITHI  60
LTVAGSLAPA YPNEFVYKVV ADKESTDLKQ HFDECFNFIE EAKRSGGVLV HCFVGKSRSV  120
TIVLAYLMKK HGMSLSEALE HVKSRRPQAS PNTGFMSQLQ AFERPETMSH IAVERNRRKQ  180
MNEHLKVLRT LTPCFYIKRG DQASIIGGVI EFIKELHQVL QSLESNKRRK KRLSPSPNPS  240
PRQPLLLLPP TPPPQLDQNP KFNFGLIDQN HDRAVKELGA CCNSPVADVE AKISGSNVVL  300
KIISRRIPGQ VVKIISVLER SSFEVLHLNI SSMEDTVLYS FVIKIGLECQ LSVEELVLEV  360
QQSLRSDTA*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4d3r_A2e-28341635137DUAL SPECIFICITY PROTEIN PHOSPHATASE 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor. Together with FMA and SPCH, regulates the stomata formation. Required for the differentiation of stomatal guard cells, by promoting successive asymmetric cell divisions and the formation of guard mother cells. Promotes the conversion of the leaf epidermis into stomata. {ECO:0000269|PubMed:17183265, ECO:0000269|PubMed:17183267}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapmrna06093.1-v1.0-hybrid
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By UV, flagellin, and jasmonic acid (JA) treatments. {ECO:0000269|PubMed:12679534}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004296942.11e-143PREDICTED: transcription factor MUTE
SwissprotQ9M8K62e-81MUTE_ARATH; Transcription factor MUTE
TrEMBLA0A498IE421e-179A0A498IE42_MALDO; Uncharacterized protein
STRINGXP_010103422.11e-174(Morus notabilis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF112523036
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G06120.12e-75bHLH family protein
Publications ? help Back to Top
  1. Casson S,Gray JE
    Influence of environmental factors on stomatal development.
    New Phytol., 2008. 178(1): p. 9-23
    [PMID:18266617]
  2. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  3. Balcerowicz M,Ranjan A,Rupprecht L,Fiene G,Hoecker U
    Auxin represses stomatal development in dark-grown seedlings via Aux/IAA proteins.
    Development, 2014. 141(16): p. 3165-76
    [PMID:25063454]
  4. de Marcos A, et al.
    Transcriptional profiles of Arabidopsis stomataless mutants reveal developmental and physiological features of life in the absence of stomata.
    Front Plant Sci, 2015. 6: p. 456
    [PMID:26157447]
  5. Mahoney AK, et al.
    Functional analysis of the Arabidopsis thaliana MUTE promoter reveals a regulatory region sufficient for stomatal-lineage expression.
    Planta, 2016. 243(4): p. 987-98
    [PMID:26748914]
  6. Klermund C, et al.
    LLM-Domain B-GATA Transcription Factors Promote Stomatal Development Downstream of Light Signaling Pathways in Arabidopsis thaliana Hypocotyls.
    Plant Cell, 2016. 28(3): p. 646-60
    [PMID:26917680]
  7. Fu ZW,Wang YL,Lu YT,Yuan TT
    Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis.
    Plant Sci., 2016. 252: p. 282-289
    [PMID:27717464]
  8. Qi X, et al.
    Autocrine regulation of stomatal differentiation potential by EPF1 and ERECTA-LIKE1 ligand-receptor signaling.
    Elife, 2018.
    [PMID:28266915]
  9. Raissig MT, et al.
    Mobile MUTE specifies subsidiary cells to build physiologically improved grass stomata.
    Science, 2017. 355(6330): p. 1215-1218
    [PMID:28302860]
  10. Lee JH,Jung JH,Park CM
    Light Inhibits COP1-Mediated Degradation of ICE Transcription Factors to Induce Stomatal Development in Arabidopsis.
    Plant Cell, 2017. 29(11): p. 2817-2830
    [PMID:29070509]
  11. Han SK, et al.
    MUTE Directly Orchestrates Cell-State Switch and the Single Symmetric Division to Create Stomata.
    Dev. Cell, 2018. 45(3): p. 303-315.e5
    [PMID:29738710]