PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID mrna03312.1-v1.0-hybrid
Organism
Fragaria vesca
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae; Fragaria
Family E2F/DP
Protein Properties Length: 333aa    MW: 36714.8 Da    PI: 9.8187
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
mrna03312.1-v1.0-hybridgenomeGDRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP68.11.1e-212390171
                  E2F_TDP  1 rkeksLrlltqkflklleksee..givtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                             rk+ksL ll+++fl+l+++ +     + l+++a++L    v   rRRiYDi+NVLe+++l+++k+kn ++wkg
  mrna03312.1-v1.0-hybrid 23 RKQKSLSLLCSNFLSLYNRDDGatVLIGLDDAASRL---GV--VRRRIYDIVNVLESVGLLSRKSKNTYTWKG 90
                             79****************9766456789********...99..9***************************98 PP
2E2F_TDP68.67.5e-22120203271
                  E2F_TDP   2 keksLrlltqkflkllek..seegivtlnevakeLvse.......dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                              +eksL ll+q+f+kl+ +  se+++++l+e+ak L+          +++k+RRiYDi+NVL+++nliek     + k+++rw g
  mrna03312.1-v1.0-hybrid 120 REKSLALLAQNFVKLFVCggSESKAISLDEAAKLLLGVgdaqnvfVMRTKVRRIYDIANVLSSVNLIEKthtadTGKPAYRWLG 203
                              79************999987888************87788****999*************************999*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.101.1E-231991IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013723.0E-262390IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023198.4E-202490IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467853.91E-142591IPR011991Winged helix-turn-helix DNA-binding domain
Gene3DG3DSA:1.10.10.108.5E-21117205IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.0E-24119203IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.5E-18121203IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467852.01E-12121204IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005667Cellular Componenttranscription factor complex
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 333 aa     Download sequence    Send to blast
MASSAVDYPP ATTTTRRDTS YSRKQKSLSL LCSNFLSLYN RDDGATVLIG LDDAASRLGV  60
VRRRIYDIVN VLESVGLLSR KSKNTYTWKG FAAVPDALKE LQEEGLDLTP IPAPVDETKR  120
EKSLALLAQN FVKLFVCGGS ESKAISLDEA AKLLLGVGDA QNVFVMRTKV RRIYDIANVL  180
SSVNLIEKTH TADTGKPAYR WLGLNGRREG LDLNSEQGKK RSFGTDLTNV SCKKSKVAEK  240
AMRNQGEAEK CNSDGCGAKE SAKSYQFGPF APVAVPRGRN GVNINKVCWE TVGACYRPQY  300
QNQAMKELFS HYREAWKLWN SQVAEKNPIR SS*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A1e-27221933226Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapmrna03312.1-v1.0-hybrid
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011460987.10.0PREDICTED: E2F transcription factor-like E2FE
SwissprotQ8LSZ41e-103E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A2P6QBP70.0A0A2P6QBP7_ROSCH; Putative transcription factor E2F-DP family
STRINGXP_008374484.11e-121(Malus domestica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-93DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]