PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID FANhyb_rscf00001306.1.g00002.1
Organism
Fragaria x ananassa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae; Fragaria
Family ARF
Protein Properties Length: 902aa    MW: 100306 Da    PI: 5.9368
Description ARF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
FANhyb_rscf00001306.1.g00002.1genomekazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B332.31.7e-102512955399
                                     EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..EEEEE-S CS
                              B3  53 rkksgryvltkGWkeFvkangLkegDfvvFkldgrsefelvvkvfrk 99 
                                      ++++r++lt+GW+ Fv+a++L +gD+v+F   ++++ +l+++++r+
  FANhyb_rscf00001306.1.g00002.1 251 YGQPKRHLLTTGWSVFVSAKRLVAGDSVLFI--WNEKNQLLLGIRRA 295
                                     567899*************************..8899999****997 PP
2Auxin_resp117.41.2e-38320403183
                      Auxin_resp   1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSk 78 
                                     aaha st+s F+v+YnPras+seFv++++k+ ka+  ++vsvGmRf+m fete+ss rr++Gt++g+sdldpvrWpnS+
  FANhyb_rscf00001306.1.g00002.1 320 AAHASSTNSCFTVFYNPRASPSEFVIPLSKYIKAVFhTRVSVGMRFRMLFETEESSVRRYMGTITGISDLDPVRWPNSH 398
                                     79*******************************986599**************************************** PP

                      Auxin_resp  79 WrsLk 83 
                                     Wrs+k
  FANhyb_rscf00001306.1.g00002.1 399 WRSVK 403
                                     **985 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019366.93E-29111184IPR015300DNA-binding pseudobarrel domain
Gene3DG3DSA:2.40.330.106.7E-35120193IPR015300DNA-binding pseudobarrel domain
CDDcd100176.41E-11126294No hitNo description
SMARTSM010190.0027127296IPR003340B3 DNA binding domain
SuperFamilySSF1019368.76E-14245323IPR015300DNA-binding pseudobarrel domain
PfamPF023626.0E-8252295IPR003340B3 DNA binding domain
PROSITE profilePS508638.6256296IPR003340B3 DNA binding domain
Gene3DG3DSA:2.40.330.106.7E-35259309IPR015300DNA-binding pseudobarrel domain
PfamPF065071.2E-33320403IPR010525Auxin response factor
SuperFamilySSF542772.68E-6770850No hitNo description
PfamPF023097.5E-8773860IPR033389AUX/IAA domain
PROSITE profilePS5174522.745776860IPR000270PB1 domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009725Biological Processresponse to hormone
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0005515Molecular Functionprotein binding
Sequence ? help Back to Top
Protein Sequence    Length: 902 aa     Download sequence    Send to blast
MKLSTSGFGQ QEGGAEKKCL NSELWHACAG PLVSLPTSGT RVVYFPQGHS DQVAATTNKQ  60
VDAHIPNYPS LPPQLICQLH NVTMHADVET DEVYAQMTLQ PLTPQEQKET FLPMELGVPS  120
KQPTNYFCKT LTASDTSTHG GFSVPRRAAE KVFPPLDFSL QPPAQELIAR DLHDVEWKFR  180
HIFRVLSRAE SFVGGKDVLI IGEKVSGLHN CMEEVVLQAV YENLCQCLGL CGATVPMTFP  240
GHNRFTCNTP YGQPKRHLLT TGWSVFVSAK RLVAGDSVLF IWNEKNQLLL GIRRATRPQT  300
VMPSSVLSSD SMHIGLLAAA AHASSTNSCF TVFYNPRASP SEFVIPLSKY IKAVFHTRVS  360
VGMRFRMLFE TEESSVRRYM GTITGISDLD PVRWPNSHWR SVKVGWDEST AGERQPRVSL  420
WEIEPLTTFP MYPSLFPLRL KRPWHPGASS MHDNRDEAAN LMWLRGGTGE QGLQSMNFQA  480
VGMFPWMQQR LDSTLMGNDP NQQYQAMLAA GLQNVGSGDQ LRQHVMHFQQ PLQYLQQPGS  540
HNPLLQLQQQ VIPQSVPHNM LQAQPQVSME NLPQHLLPPQ FNNQTEEEPH QQQNTYHDAL  600
KVQSEQLHQS QQMNVPSPSF SRADYTDSST KLLGSTNSRQ NTLGSLCPEG SNSVLNRAGP  660
AEQLPQQSWT PKFGYAQANA FANPMSFAPF NEKDNAVEQE NCNSDSQNPT LFGVNIESSG  720
LVFPTTVPNF ATSSNDADMP MPLGDSGFQS SLYGCIQDSS ELLHGAGQVD PPTPNCTFVK  780
VYKSGSVGRS LDISRFSSYN QLREELAQMF GIEGKLEDCL RSGWQLVFVD REDDVLLLGD  840
DPWESFVNNV WYIKILSPED VHKMGDQAVD SFTPNVGQRV NSSANETQDH ISGLPSLGSL  900
EY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4ldu_A2e-691042441388Auxin response factor 5
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtAuxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Regulates both stamen and gynoecium maturation. Promotes jasmonic acid production. Partially redundant with ARF6. Involved in fruit initiation. Acts as an inhibitor to stop further carpel development in the absence of fertilization and the generation of signals required to initiate fruit and seed development. {ECO:0000269|PubMed:12036261, ECO:0000269|PubMed:16107481, ECO:0000269|PubMed:16829592}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by miR167. {ECO:0000269|PubMed:17021043}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004288582.10.0PREDICTED: auxin response factor 8
SwissprotQ9FGV10.0ARFH_ARATH; Auxin response factor 8
TrEMBLA0A445LT240.0A0A445LT24_GLYSO; Auxin response factor
STRINGXP_004288582.10.0(Fragaria vesca)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF49582850
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G37020.10.0auxin response factor 8
Publications ? help Back to Top
  1. Liu N, et al.
    Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.
    J. Exp. Bot., 2014. 65(9): p. 2507-20
    [PMID:24723401]
  2. Minato N, et al.
    The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.
    Sci Rep, 2014. 4: p. 7399
    [PMID:25492247]
  3. Ortega-Amaro MA, et al.
    Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.
    Front Plant Sci, 2014. 5: p. 782
    [PMID:25653657]
  4. Wang Y, et al.
    MicroRNA167-Directed Regulation of the Auxin Response Factors GmARF8a and GmARF8b Is Required for Soybean Nodulation and Lateral Root Development.
    Plant Physiol., 2015. 168(3): p. 984-99
    [PMID:25941314]
  5. Barik S, et al.
    Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.
    Sci Rep, 2015. 5: p. 14611
    [PMID:26459056]
  6. Pashkovskiy PP,Kartashov AV,Zlobin IE,Pogosyan SI,Kuznetsov VV
    Blue light alters miR167 expression and microRNA-targeted auxin response factor genes in Arabidopsis thaliana plants.
    Plant Physiol. Biochem., 2016. 104: p. 146-54
    [PMID:27031426]
  7. Mlotshwa S,Pruss GJ,MacArthur JL,Reed JW,Vance V
    Developmental Defects Mediated by the P1/HC-Pro Potyviral Silencing Suppressor Are Not Due to Misregulation of AUXIN RESPONSE FACTOR 8.
    Plant Physiol., 2016. 172(3): p. 1853-1861
    [PMID:27688620]
  8. Wójcikowska B,Gaj MD
    Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.
    Plant Cell Rep., 2017. 36(6): p. 843-858
    [PMID:28255787]
  9. Zhang GZ, et al.
    Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.
    Plant Cell Rep., 2017. 36(12): p. 1995-2006
    [PMID:29027578]
  10. Zheng K, et al.
    Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.
    Front Plant Sci, 2017. 8: p. 1813
    [PMID:29114256]
  11. Liu Z, et al.
    ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
    Plant Cell Physiol., 2018. 59(1): p. 179-189
    [PMID:29145642]
  12. Ghelli R, et al.
    A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.
    Plant Cell, 2018. 30(3): p. 620-637
    [PMID:29514943]