PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID FANhyb_rscf00000078.1.g00007.1
Organism
Fragaria x ananassa
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae; Fragaria
Family HD-ZIP
Protein Properties Length: 819aa    MW: 90814.2 Da    PI: 6.8342
Description HD-ZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
FANhyb_rscf00000078.1.g00007.1genomekazusaView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox62.85.2e-202075156
                                    TT--SS--HHHHHHHHHHHHHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHHH CS
                        Homeobox  1 rrkRttftkeqleeLeelFeknrypsaeereeLAkklgLterqVkvWFqNrRakek 56
                                    +++ +++t++q+++Le++F+ +++p++++r +L+++lgL  rq+k+WFqNrR+++k
  FANhyb_rscf00000078.1.g00007.1 20 KKRYHRHTSNQIQRLEAMFKDCPHPDEKQRLQLSRELGLAPRQIKFWFQNRRTQMK 75
                                    678899***********************************************998 PP
2START181.25.9e-573105342206
                                     HHHHHHHHHHHHHHHC-TT-EEEE....EXCCTTEEEEEEESSS.......SCEEEEEEEECCSCHHHHHHHHHCCCGG CS
                           START   2 laeeaaqelvkkalaeepgWvkss....esengdevlqkfeeskv......dsgealrasgvvdmvlallveellddke 70 
                                     +a  a++el+++ + ++p+W+kss    + +n + + ++f+++ +       ++ea+rasgvv+m+   lv  ++d ++
  FANhyb_rscf00000078.1.g00007.1 310 IAANAMEELLRLLQTNDPLWMKSStdgkDVLNLESYDRIFPRATThlknpnLRIEASRASGVVIMNGLALVDMIMDPNK 388
                                     67889*******************999888999999999999888*********************************6 PP

                                     ...CT-TT-SEEEEEEEECTT......EEEEEEEEXXTTXX-SSX.EEEEEEEEEEE.TTS-EEEEEEEEE-TTS--.- CS
                           START  71 ...qWdetlakaetlevissg......galqlmvaelqalsplvp.RdfvfvRyirqlgagdwvivdvSvdseqkppes 139
                                         + + +  a t+evissg      g+lqlm+ elq+lsplvp R+f+f+Ry+ q ++g w+ivdvS d +++++  
  FANhyb_rscf00000078.1.g00007.1 389 fgeLFPTIVSMARTIEVISSGmlgshsGTLQLMYKELQLLSPLVPtREFYFLRYCHQIEQGHWAIVDVSYDFPRDNQ-F 466
                                     7767777777******************************************************************9.8 PP

                                     TTSEE-EESSEEEEEEEECTCEEEEEEEE-EE--SSXX.HHHHHHHHHHHHHHHHHHHHHHTXXXXXX CS
                           START 140 ssvvRaellpSgiliepksnghskvtwvehvdlkgrlp.hwllrslvksglaegaktwvatlqrqcek 206
                                     ++  R+++lpSg+li++++ng+skvtwvehv+ +++ p h l+r l++sg+a+ga +w+ +lqr ce+
  FANhyb_rscf00000078.1.g00007.1 467 ANQSRSHRLPSGCLIQDMPNGYSKVTWVEHVEIEEKAPiHRLYRDLIHSGQAFGAERWLVALQRMCER 534
                                     ******************************************************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.601.7E-22571IPR009057Homeodomain-like
SuperFamilySSF466895.85E-201281IPR009057Homeodomain-like
PROSITE profilePS5007117.881777IPR001356Homeobox domain
SMARTSM003891.6E-191881IPR001356Homeobox domain
CDDcd000861.00E-181978No hitNo description
PfamPF000461.2E-172075IPR001356Homeobox domain
PROSITE patternPS0002705275IPR017970Homeobox, conserved site
PROSITE profilePS5084851.091300537IPR002913START domain
SuperFamilySSF559611.16E-40301536No hitNo description
CDDcd088757.83E-115304533No hitNo description
SMARTSM002342.6E-48309534IPR002913START domain
Gene3DG3DSA:3.30.530.208.7E-9310504IPR023393START-like domain
PfamPF018521.5E-48310534IPR002913START domain
SuperFamilySSF559611.92E-25555784No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009828Biological Processplant-type cell wall loosening
GO:0010091Biological Processtrichome branching
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008289Molecular Functionlipid binding
Sequence ? help Back to Top
Protein Sequence    Length: 819 aa     Download sequence    Send to blast
MEFGGGSGGD HDGSDSHRRK KRYHRHTSNQ IQRLEAMFKD CPHPDEKQRL QLSRELGLAP  60
RQIKFWFQNR RTQMKAQHER ADNSALRSEN DQIRCENIAI REALKNVICP SCGVPPINED  120
SYFDEHKLRM ENAQLKEELD RVSSIAAKYI GRPISQLPPV QPRNNFAQHE RADNSVLRSE  180
NDKIRCENIA IREALKNVIC PSCGVPPINE DNYFDEHKLR MENAQLKEEL DRVSSIAAKY  240
IGRPISQLPP VQPIHISSLD LSMASFGGHG MGGPSLDLDL LPGSTSSTMP SLPYQPIGIS  300
DMDKSLMTDI AANAMEELLR LLQTNDPLWM KSSTDGKDVL NLESYDRIFP RATTHLKNPN  360
LRIEASRASG VVIMNGLALV DMIMDPNKFG ELFPTIVSMA RTIEVISSGM LGSHSGTLQL  420
MYKELQLLSP LVPTREFYFL RYCHQIEQGH WAIVDVSYDF PRDNQFANQS RSHRLPSGCL  480
IQDMPNGYSK VTWVEHVEIE EKAPIHRLYR DLIHSGQAFG AERWLVALQR MCERYACLMV  540
SGTSTRDLEG VIPSPEGKRS MMKLAQRMVN NFCASISTSN GHRWTTISGM NEVGVRVTIH  600
KSTDPGQPNG VVLSAATTIW LPLSPQTVFN FFKDERTRPQ WDVLSNGNAV QEVAHIANGS  660
HPGNCISVLR AFNTSQNNML ILQESCIDSS GSLVVYCPVD LPAINIAMSG EDPSYIPLLP  720
SGFTITPDGR QDQGDTSAST SSCSNINHIG GSGSLITVAF QILVSSLPSA KLNMESVNTV  780
NNLIGTTKAG GIELMVPGTK HMGLVGSLNA LSSRPEALH
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA (PubMed:18451323). Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth (PubMed:24821957). Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation (PubMed:25752924). Acts as negative regulator of trichome branching (PubMed:16778018, PubMed:24824485). Required for the establishment of giant cell identity on the abaxial side of sepals (PubMed:23095885). May regulate cell differentiation and proliferation during root and shoot meristem development (PubMed:25564655). {ECO:0000269|PubMed:16778018, ECO:0000269|PubMed:18451323, ECO:0000269|PubMed:23095885, ECO:0000269|PubMed:24821957, ECO:0000269|PubMed:24824485, ECO:0000269|PubMed:25564655, ECO:0000269|PubMed:25752924}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00232DAPTransfer from AT1G73360Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_004299483.10.0PREDICTED: homeobox-leucine zipper protein HDG11
SwissprotQ9FX310.0HDG11_ARATH; Homeobox-leucine zipper protein HDG11
TrEMBLA0A2P6P1K50.0A0A2P6P1K5_ROSCH; Putative transcription factor & lipid binding Homobox-WOX family
STRINGXP_004299483.10.0(Fragaria vesca)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF10263398
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G73360.10.0homeodomain GLABROUS 11
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Khosla A, et al.
    HD-Zip Proteins GL2 and HDG11 Have Redundant Functions in Arabidopsis Trichomes, and GL2 Activates a Positive Feedback Loop via MYB23.
    Plant Cell, 2014. 26(5): p. 2184-2200
    [PMID:24824485]
  3. Horstman A, et al.
    AIL and HDG proteins act antagonistically to control cell proliferation.
    Development, 2015. 142(3): p. 454-64
    [PMID:25564655]
  4. Cai XT,Xu P,Wang Y,Xiang CB
    Activated expression of AtEDT1/HDG11 promotes lateral root formation in Arabidopsis mutant edt1 by upregulating jasmonate biosynthesis.
    J Integr Plant Biol, 2015. 57(12): p. 1017-30
    [PMID:25752924]
  5. Yu LH, et al.
    Arabidopsis EDT1/HDG11 improves drought and salt tolerance in cotton and poplar and increases cotton yield in the field.
    Plant Biotechnol. J., 2016. 14(1): p. 72-84
    [PMID:25879154]
  6. Zhu Z, et al.
    Overexpression of AtEDT1/HDG11 in Chinese Kale (Brassica oleracea var. alboglabra) Enhances Drought and Osmotic Stress Tolerance.
    Front Plant Sci, 2016. 7: p. 1285
    [PMID:27625663]
  7. Liu Y, et al.
    Overexpression of AtEDT1 promotes root elongation and affects medicinal secondary metabolite biosynthesis in roots of transgenic Salvia miltiorrhiza.
    Protoplasma, 2017. 254(4): p. 1617-1625
    [PMID:27915455]
  8. Ueda M, et al.
    Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote.
    Genes Dev., 2017. 31(6): p. 617-627
    [PMID:28404632]
  9. Lung SC, et al.
    Arabidopsis ACYL-COA-BINDING PROTEIN1 interacts with STEROL C4-METHYL OXIDASE1-2 to modulate gene expression of homeodomain-leucine zipper IV transcription factors.
    New Phytol., 2018. 218(1): p. 183-200
    [PMID:29288621]
  10. Zheng G, et al.
    Over-Expression of Arabidopsis EDT1 Gene Confers Drought Tolerance in Alfalfa (Medicago sativa L.).
    Front Plant Sci, 2017. 8: p. 2125
    [PMID:29326737]