PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

FANhyb_icon00040458_a.1.g00001.1

Organism

Fragaria x ananassa

Taxonomic ID

3747

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Rosales; Rosaceae; Rosoideae; Potentilleae; Fragariinae; Fragaria

Family

E2F/DP

Protein Properties

Length: 66aa MW: 7339.23 Da PI: 8.4915

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
FANhyb_icon00040458_a.1.g00001.1	genome	kazusa	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	58	1.5e-18	15	65	1	56
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLeal 56 rk+ksL+ll+++f++l+ ++ + + l+++a++L v +rRRiYDi+NVLe++ FANhyb_icon00040458_a.1.g00001.1 15 RKQKSLGLLCSNFISLYDREGVTSIGLDDAASKL---GV--ERRRIYDIVNVLESV 65 79***************999********.....*************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	6.9E-21	10	66	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	1.5E-12	14	66	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	3.7E-11	15	66	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	8.4E-16	16	66	IPR003316	E2F/DP family, winged-helix DNA-binding domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 66 aa Download sequence Send to blast
TQPETASTRH HSYSRKQKSL GLLCSNFISL YDREGVTSIG LDDAASKLGV ERRRIYDIVN 60 VLESVG

Functional Description ? help Back to Top
Source	Description
UniProt	Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11867638, ECO:0000269\|PubMed:15649366, ECO:0000269\|PubMed:18787127}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011464534.1	1e-38	PREDICTED: E2F transcription factor-like E2FE isoform X3
Swissprot	Q8LSZ4	3e-29	E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBL	A0A2P6P273	1e-30	A0A2P6P273_ROSCH; Putative transcription factor E2F-DP family
STRING	XP_004301283.1	6e-38	(Fragaria vesca)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Fabids	OGEF21774	3	4

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G48160.2	1e-31	DP-E2F-like 1

Publications ? help Back to Top
Chandran D, et al. Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid. Cell Host Microbe, 2014. 15(4): p. 506-13 [PMID:24721578] Wang Z, et al. Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis. PLoS ONE, 2016. 11(8): p. e0160684 [PMID:27505251] Heyman J,Polyn S,Eekhout T,De Veylder L Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1. Plant Physiol., 2017. 175(1): p. 303-313 [PMID:28698355]