PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 462857050
Organism
Eragrostis tef
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Eragrostideae; Eragrostidinae; Eragrostis
Family MYB
Protein Properties Length: 147aa    MW: 16664.9 Da    PI: 11.3148
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
462857050genomeTefView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding46.86.9e-151763147
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47
                     +g+WT+eEd  l + v+++G + W++I ++ +++Rt+k+c++r+ + 
        462857050 17 KGPWTAEEDAVLRRHVEEHGREKWSSIQSKGPLRRTGKSCRLRYVNI 63
                     79******************************************986 PP
2Myb_DNA-binding46.67.6e-1570114147
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 
                      +g+++++E++   +  +++G++ W+ Ia++++ gRt++++k++w ++
        462857050  70 KGPFSEDEQKTVFEMQREHGNK-WSMIAKKLP-GRTDNDVKNFWSTH 114
                      79********************.*********.***********876 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129412.7731263IPR017930Myb domain
SuperFamilySSF466892.25E-2815111IPR009057Homeodomain-like
SMARTSM007171.5E-121666IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.2E-221871IPR009057Homeodomain-like
CDDcd001675.01E-101964No hitNo description
PfamPF139215.3E-142079No hitNo description
PROSITE profilePS5129423.45965119IPR017930Myb domain
SMARTSM007173.1E-1469117IPR001005SANT/Myb domain
CDDcd001673.04E-1072114No hitNo description
Gene3DG3DSA:1.10.10.604.0E-2172117IPR009057Homeodomain-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 147 aa     Download sequence    Send to blast
MAPRRRGGGD PPATVKKGPW TAEEDAVLRR HVEEHGREKW SSIQSKGPLR RTGKSCRLRY  60
VNILDPELKK GPFSEDEQKT VFEMQREHGN KWSMIAKKLP GRTDNDVKNF WSTHQKRLQR  120
NGGGGGGPPI SVAAVRQRDL MRGSLNR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1h8a_C2e-251511725126MYB TRANSFORMING PROTEIN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that acts as a positive regulator of male germline development by promoting both gametic cell specification and cell cycle progression (PubMed:15694308, PubMed:15618418, PubMed:19300502, PubMed:21285328). Binds to canonical MYB sites 5'-AACCGTC-3', 5'-AAACCGC-3' and 5'-AACCGT-3' in promoters to trigger the expression of male germline-specific or enriched genes (e.g. MGH3, GEX2 and GCS1), including those required for fertilization (PubMed:21285328, PubMed:19300502). Required for sperm cell specification leading to pollen maturation by activating a germline-specific regulon (PubMed:21285328, PubMed:15694308, PubMed:15618418, PubMed:19300502). Involved in pollen mitosis entry at G2-M transition via the regulation of CYCB1-1, DAZ1 and DAZ2 expression (PubMed:15618418, PubMed:19300502, PubMed:24876252). {ECO:0000269|PubMed:15618418, ECO:0000269|PubMed:15694308, ECO:0000269|PubMed:19300502, ECO:0000269|PubMed:21285328, ECO:0000269|PubMed:24876252}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap462857050
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by the microRNA 159 (miR159); the production of miR159 is stimulated by the anaphase promoting complex/cyclosome (APC/C) (PubMed:21441434). Activated by ARID1 in male germline cells via specific histone acetylation regulation (e.g. H3K9Ac) (PubMed:25057814). {ECO:0000269|PubMed:21441434, ECO:0000269|PubMed:25057814}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020201575.14e-43transcription factor MYB21-like
RefseqXP_024317615.17e-43transcription factor MYB80-like
SwissprotA0A178VEK77e-42DUO1_ARATH; Transcription factor DUO1
TrEMBLA0A1E5VYD26e-43A0A1E5VYD2_9POAL; Transcription factor GAMYB
TrEMBLA0A287WH671e-44A0A287WH67_HORVV; Uncharacterized protein
STRINGSi015815m2e-43(Setaria italica)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP57003357
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G60460.12e-44MYB family protein
Publications ? help Back to Top
  1. Zheng B,He H,Zheng Y,Wu W,McCormick S
    An ARID domain-containing protein within nuclear bodies is required for sperm cell formation in Arabidopsis thaliana.
    PLoS Genet., 2014. 10(7): p. e1004421
    [PMID:25057814]
  2. Peters B, et al.
    A Conserved cis-Regulatory Module Determines Germline Fate through Activation of the Transcription Factor DUO1 Promoter.
    Plant Physiol., 2017. 173(1): p. 280-293
    [PMID:27624837]
  3. Zheng Z, et al.
    Target RNA Secondary Structure Is a Major Determinant of miR159 Efficacy.
    Plant Physiol., 2017. 174(3): p. 1764-1778
    [PMID:28515145]