PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 462856161
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Eragrostideae; Eragrostidinae; Eragrostis
Family C2H2
Protein Properties Length: 328aa    MW: 35746.3 Da    PI: 9.4319
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
462856161genomeTefView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H219.42.8e-064163123
               EEETTTTEEESSHHHHHHHHHHT CS
    zf-C2H2  1 ykCpdCgksFsrksnLkrHirtH 23
               ++C++Cgk F r  nL+ H r H
  462856161 41 FVCEICGKGFQRDQNLQLHRRGH 63
               89*******************88 PP

2zf-C2H213.30.00025121143123
                EEETTTTEEESSHHHHHHHHHHT CS
    zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                +kC +C+k++  +s+ k H +t+
  462856161 121 WKCDKCSKRYAVQSDWKAHGKTC 143
                58*****************9987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576671.17E-74063No hitNo description
SMARTSM003550.0124163IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.6144163IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.608.4E-64163IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS0002804363IPR007087Zinc finger, C2H2
SMARTSM0035525086116IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.603.0E-4109142IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576671.17E-7116141No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 328 aa     Download sequence    Send to blast
MSKNPNPGLM ATSNNELEQA QDPDAEVIAL SPRTLLATNR FVCEICGKGF QRDQNLQLHR  60
RGHNLPWKLK QSNGAAGNNR RRKRVYVCPE TSCVHHNPSR ALGDLTGIKK HFCRKHGEKK  120
WKCDKCSKRY AVQSDWKAHG KTCGTREYRC DCGTLFSRRD SFITHRAFCD ALAQETARRN  180
LSLWGDQAAA TGGDAAELVM PPSELLTSTA SKDSVVPSLF SRQHLAAAKP AAVADMSATA  240
LLHKAAQIGA VVTSNHSNSS ISSSCTATTP SQVLVDGLLF AGQHHHATSS SSSSSLANLR  300
PYLNKGREEE TRDFLGVALC SPSLHGWI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_C7e-35117178364Zinc finger protein JACKDAW
5b3h_F7e-35117178364Zinc finger protein JACKDAW
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269|PubMed:25035403}.
UniProtTranscription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269|PubMed:17785527, ECO:0000269|PubMed:21935722, ECO:0000269|PubMed:24821766, ECO:0000269|PubMed:25829440}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap462856161
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269|PubMed:21935722}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_008655812.11e-113zinc finger protein NUTCRACKER
RefseqXP_008673471.11e-113zinc finger protein NUTCRACKER
SwissprotQ9SCQ61e-101IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
SwissprotQ9ZWA61e-100IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBLQ5NA811e-124Q5NA81_ORYSJ; Os01g0242200 protein
STRINGOS01T0242200-011e-125(Oryza sativa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP20238320
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G50700.11e-100indeterminate(ID)-domain 2
Publications ? help Back to Top
  1. Fukazawa J, et al.
    DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis.
    Plant Cell, 2014. 26(7): p. 2920-38
    [PMID:25035403]
  2. Muñoz-Strale D,León G
    Identification of two highly specific pollen promoters using transcriptomic data.
    Plant Physiol. Biochem., 2014. 83: p. 292-9
    [PMID:25208507]
  3. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]
  4. Khare D, et al.
    Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana.
    New Phytol., 2017. 213(3): p. 1257-1273
    [PMID:27768815]